2024
Meta-analysis identifies common gut microbiota associated with multiple sclerosis
Lin Q, Dorsett Y, Mirza A, Tremlett H, Piccio L, Longbrake E, Choileain S, Hafler D, Cox L, Weiner H, Yamamura T, Chen K, Wu Y, Zhou Y. Meta-analysis identifies common gut microbiota associated with multiple sclerosis. Genome Medicine 2024, 16: 94. PMID: 39085949, PMCID: PMC11293023, DOI: 10.1186/s13073-024-01364-x.Peer-Reviewed Original ResearchConceptsRRNA gene sequence dataGroups of microbial taxaGene sequence dataMicrobiome community structureAbundance of FaecalibacteriumAbundance of PrevotellaAbundance of ActinomycesSequence dataBeta diversityMicrobial taxaGut microbiotaMicrobial compositionCommunity structureNetwork analysisGutBacterial correlationsMicrobiotaAbundanceMultiple sclerosisDiverse groupMeta-analysisDiversityTaxaFaecalibacteriumConclusionsOur meta-analysis
2015
Class II HLA interactions modulate genetic risk for multiple sclerosis
Moutsianas L, Jostins L, Beecham A, Dilthey A, Xifara D, Ban M, Shah T, Patsopoulos N, Alfredsson L, Anderson C, Attfield K, Baranzini S, Barrett J, Binder T, Booth D, Buck D, Celius E, Cotsapas C, D'Alfonso S, Dendrou C, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud P, Graetz C, Hemmer B, Hillert J, Consortium I, Kockum I, Leslie S, Lill C, Martinelli-Boneschi F, Oksenberg J, Olsson T, Oturai A, Saarela J, Søndergaard H, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines J, Pericak-Vance M, Spencer C, Stewart G, Hafler D, Ivinson A, Harbo H, Hauser S, De Jager P, Compston A, McCauley J, Sawcer S, McVean G. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature Genetics 2015, 47: 1107-1113. PMID: 26343388, PMCID: PMC4874245, DOI: 10.1038/ng.3395.Peer-Reviewed Original Research