Todd Schlachter, MD
Associate Professor of Radiology and Biomedical ImagingCards
About
Research
Overview
Medical Research Interests
Biliary Tract Diseases; Hypertension, Pulmonary; Lithotripsy; Lithotripsy, Laser; Liver Circulation; Liver Transplantation; Pediatrics; Portal System; Vascular Malformations
Publications
Featured Publications
Cryoablation of Venous Malformations: A Systematic Review
Fish A, Moushey A, Chan SM, Staib L, Marino A, Schlachter T. Cryoablation of Venous Malformations: A Systematic Review. Journal Of Vascular And Interventional Radiology 2022, 33: 993-1000. PMID: 35469956, DOI: 10.1016/j.jvir.2022.04.010.Peer-Reviewed Original ResearchConceptsPain scoresVenous malformationsPercutaneous cryoablationLesion volumeClinical studiesLesion sizePostprocedural pain scoresWeighted mean reductionMajor adverse eventsCases of cryoablationPersistent dysesthesiaPostprocedural changesPostprocedural decreaseRandom effects analysisAdverse eventsPatient characteristicsCryoablation techniqueAdverse outcomesTechnical successComplete resolutionPostprocedural symptomsMean reductionCryoablationPrior treatmentSystematic reviewTranspleural Systemic Artery-to-Pulmonary Artery Shunts: A Potential Mimicker of Pulmonary Arteriovenous Malformations
Fish A, Chan SM, Pollak J, Schlachter T. Transpleural Systemic Artery-to-Pulmonary Artery Shunts: A Potential Mimicker of Pulmonary Arteriovenous Malformations. Journal Of Vascular And Interventional Radiology 2022, 34: 300-303. PMID: 36283590, DOI: 10.1016/j.jvir.2022.10.028.Peer-Reviewed Original ResearchResearch Priorities in Percutaneous Image- and Endoscopy-Guided Interventions for Biliary and Gallbladder Diseases: Proceedings from the Society of Interventional Radiology Foundation Multidisciplinary Research Consensus Panel
Riaz A, Trivedi P, Aadam AA, Katariya N, Matsuoka L, Malik A, Gunn AJ, Vezeridis A, Sarwar A, Schlachter T, Harmath C, Srinivasa R, Abi-Jaoudeh N, Singh H. Research Priorities in Percutaneous Image- and Endoscopy-Guided Interventions for Biliary and Gallbladder Diseases: Proceedings from the Society of Interventional Radiology Foundation Multidisciplinary Research Consensus Panel. Journal Of Vascular And Interventional Radiology 2022, 33: 1247-1257. PMID: 35809805, DOI: 10.1016/j.jvir.2022.06.025.Peer-Reviewed Original ResearchConceptsGallbladder diseaseInterventional radiologyPercutaneous imageConsensus panelAnastomotic biliary stricturesProspective research studyIntraductal cholangiocarcinomaNonsurgical patientsCalculous cholecystitisMultimodality managementPercutaneous drainBiliary stricturesPatients' qualityStent placementClinical relevanceResearch prioritiesDiseaseMultidisciplinary groupTotal durationPatientsManagement protocolCurrent dataUnanswered questionsCholecystitisCholedochoscopySafety and feasibility of single use cholecystoscopy for guiding laser or mechanical cholelithotripsy, and mechanical cholelithotomy
Nezami N, Division of Interventional Radiology and Image-Guided Medicine D, Latich I, Chockalingam A, Arici M, Lee J, Lozada J, Schlachter T, Division of Vascular and Interventional Radiology D, Department of Surgery B, Department of Radiology M. Safety and feasibility of single use cholecystoscopy for guiding laser or mechanical cholelithotripsy, and mechanical cholelithotomy. Diagnostic And Interventional Radiology 2022, 28: 352-358. PMID: 35950279, PMCID: PMC9634924, DOI: 10.5152/dir.2022.20810.Peer-Reviewed Original ResearchConceptsAcute calculus cholecystitisCalculus cholecystitisCatheter placementClinical successSingle-institute retrospective analysisCommon bile duct stonesMinor procedure-related complicationsEarly clinical outcomesProcedure-related complicationsBile duct stonesMedian time intervalMean interval timeNumber of interventionsGallstone extractionCholecystostomy tubeEnd of lifeMorbid obesitySurgical contraindicationsSymptomatic cholelithiasisClinical outcomesDuct stonesCardiopulmonary diseaseDrainage catheterPurpose PatientsRetrospective analysis
2024
Criteria for PAVM Reintervention
Fish A, Knight E, Henderson K, Pollak J, Schlachter T. Criteria for PAVM Reintervention. Journal Of Clinical Medicine 2024, 13: 6104. PMID: 39458055, PMCID: PMC11508501, DOI: 10.3390/jcm13206104.Peer-Reviewed Original ResearchParadoxical embolismRetrospective review of patientsReview of patientsModern embolization techniquesRetrospective reviewEmbolization techniquesReinterventionScreening intervalEmbolizationLifetime prevalence ratesPatientsRecurrencePAVMsHemoptysisSpontaneous eventsPrevalence ratesCenters of excellenceReperfusionCriteriaRecurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension
Fish A, Wang D, Knight E, Pollak J, Schlachter T. Recurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension. Journal Of Vascular And Interventional Radiology 2024, 35: 1148-1153. PMID: 38692392, DOI: 10.1016/j.jvir.2024.04.017.Peer-Reviewed Original ResearchPulmonary arteriovenous malformationsPulmonary hypertensionArteriovenous malformationsRecurrence of pulmonary arteriovenous malformationsFollow-upChest CT follow-upPresence of pulmonary hypertensionCT follow-upShorter surveillance intervalsPulmonary artery pressureHistory of smokingPresence of PHCuracao criteriaSurveillance intervalsSmoking historyArterial pressureMultivariate analysisRecurrenceGenetic testingOdds ratioHypertensionPatientsStratified analysisGeneral demographicsStudy period
2022
Conventional vs. Drug-Eluting Beads Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma—A Propensity Score Weighted Comparison of Efficacy and Safety
Savic L, Chen E, Nezami N, Murali N, Hamm C, Wang C, Lin M, Schlachter T, Hong K, Georgiades C, Chapiro J, Gaupp F. Conventional vs. Drug-Eluting Beads Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma—A Propensity Score Weighted Comparison of Efficacy and Safety. Cancers 2022, 14: 5847. PMID: 36497329, PMCID: PMC9738175, DOI: 10.3390/cancers14235847.Peer-Reviewed Original ResearchImpact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model
Berz AM, Santana JG, Iseke S, Gross M, Pekurovsky V, Laage Gaupp F, Savic LJ, Borde T, Gottwald LA, Boustani AM, Gebauer B, Lin M, Zhang X, Schlachter T, Madoff DC, Chapiro J. Impact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model. Journal Of Vascular And Interventional Radiology 2022, 33: 764-774.e4. PMID: 35346859, PMCID: PMC9344951, DOI: 10.1016/j.jvir.2022.03.026.Peer-Reviewed Original ResearchConceptsTranscatheter arterial chemoembolizationCytotoxic T-lymphocyte-associated protein 4Rabbit liver tumor modelConventional TACEImmune checkpoint marker expressionLiver tumor modelVX2 rabbit liver tumor modelArterial chemoembolizationBicarbonate infusionImmune responseDifferentiation 3T-lymphocyte-associated protein 4Conventional transcatheter arterial chemoembolizationTumor modelCell death protein 1Marker expressionIntratumoral T cellsImmune checkpoint markersT cell infiltrationDeath protein 1Antigen-presenting cellsImmune cell recruitmentNew Zealand white rabbitsZealand white rabbitsAPC infiltrationInterventional radiology
Brejt S, Sobolevsky S, Schlachter T, Chapiro J, Duran R, Tacher V, Zamboni C, Higgins L, Geschwind J. Interventional radiology. 2022, 2774-2803. DOI: 10.1002/9781119600206.ch139.Peer-Reviewed Original ResearchInterventional radiologyPercutaneous therapyTransjugular liver biopsySecondary hepatic malignanciesTreatment of patientsGastrojejunostomy tubeGastrostomy tractLiver biopsyHepatic malignanciesLess painOpen surgeryLess recovery timeLiver cancerAbdominal wallLiver capsuleInterventional oncologyMultidisciplinary teamOrgan systemsMultiple specialtiesIR proceduresLess riskTherapyRadiologyRecovery timePain
2021
Quantitative Automated Segmentation of Lipiodol Deposits on Cone-Beam CT Imaging Acquired during Transarterial Chemoembolization for Liver Tumors: A Deep Learning Approach
Malpani R, Petty CW, Yang J, Bhatt N, Zeevi T, Chockalingam V, Raju R, Petukhova-Greenstein A, Santana JG, Schlachter TR, Madoff DC, Chapiro J, Duncan J, Lin M. Quantitative Automated Segmentation of Lipiodol Deposits on Cone-Beam CT Imaging Acquired during Transarterial Chemoembolization for Liver Tumors: A Deep Learning Approach. Journal Of Vascular And Interventional Radiology 2021, 33: 324-332.e2. PMID: 34923098, PMCID: PMC8972393, DOI: 10.1016/j.jvir.2021.12.017.Peer-Reviewed Original Research
Clinical Care
Overview
Todd Schlachter, MD, is an Assistant Professor of Radiology and Biomedical Imaging at the Yale School of Medicine, whose research interests include liver cancer and diseases involving the liver.
Dr. Schlachter completed his surgical intern year at the University of Pennsylvania School of Medicine and his Radiology Residency from the University of Connecticut School of Medicine. After finishing his Interventional Radiology fellowship at Johns Hopkins School of Medicine in 2012, he was hired as an Attending where he focused on treating a wide range of vascular diseases including liver cancer.
Dr. Schlachter is committed to working together to determine the most effective treatments for his patients.
Clinical Specialties
Radiology & Biomedical Imaging; Non-Invasive Vascular Imaging; Interventional Radiology; Pediatric Interventional Radiology
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Interventional Radiology Team
333 CEDAR ST, PO box 208042
NEW HAVEN, CONNECTICUT 06510
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Tompkins East Building
Academic Office
789 Howard Avenue
New Haven, CT 06519
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