Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsMiriam Treggiari, MD, PhD, MPH
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About
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Titles
Professor Adjunct
Vice Chair of Clinical Research, Anesthesiology
Biography
Dr. Miriam Treggiari is Professor and Vice Chair of Clinical Research in the Department of Anesthesiology at the Yale School of Medicine. Before joining Yale, she was Endowed Professor and Vice Chair for Research at the Oregon Health and Science University. She is an internationally recognized leader in the area of clinical and outcomes research in the perioperative setting with special emphasis in critically ill and neurocritical care patients.
Dr. Treggiari received her medical training in Italy and Switzerland. Following her anesthesiology residency, she completed a fellowship in Critical Care Medicine at the Geneva University Hospital, Switzerland. She earned an MPH in Epidemiology at the University of Washington, School of Public Health and Community Medicine. In 2007, she completed a PhD in Epidemiology at the University of Washington.
Last Updated on April 07, 2025.
Appointments
Education & Training
- PhD
- University of Washington, Epidemiology (2007)
- MPH
- University of Washington, Epidemiology (2002)
- Fellow
- Geneva University Hospitals (1998)
- Resident
- Geneva University Hospitals (1997)
- Intern
- Civico Hospital (1993)
- MD
- University of Pavia (1990)
Research
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Overview
Medical Research Interests
Anesthesiology; Critical Care; Epidemiology; Perioperative Care
ORCID
0000-0003-4639-3682
Research at a Glance
Yale Co-Authors
Frequent collaborators of Miriam Treggiari's published research.
Publications Timeline
A big-picture view of Miriam Treggiari's research output by year.
Research Interests
Research topics Miriam Treggiari is interested in exploring.
Emily Sharp, PhD, ABPP
Jinlei Li, MD, PhD
Amit Bardia, MD
Christopher Tormey, MD
Clark Fisher, MD, PhD
Elaine Fajardo, MD
149Publications
5,461Citations
Critical Care
Perioperative Care
Anesthesiology
Publications
2025
Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation (PreVent 2): a randomised controlled phase 2 trial
Treggiari M, Sharp E, Ohnuma T, Fajardo E, Aydin A, Akhtar S, Kampp M, Hashemaghaie M, Potnis A, Gugel T, Simon J, Curry L, Adams K, Darji B, Sureshanand S, Hintz R, Lorzano S, Johnson C, Yanez N. Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation (PreVent 2): a randomised controlled phase 2 trial. The Lancet Respiratory Medicine 2025 PMID: 41319662, DOI: 10.1016/s2213-2600(25)00294-2.Peer-Reviewed Original ResearchCitationsAltmetricConceptsInfection-related ventilator-associated complicationsQuality of lifeVentilator-associated pneumoniaControlled phase 2 trialPhase 2 trialSubglottic suctioningEndotracheal tubeCognitive functionNational InstituteEmergency intubationLaryngeal injuryUsual careFollow-upLong-term outcome differencesEmergency departmentFollow-up visitBlood InstituteSubglottic drainageVentilator-associated complicationsEndotracheal tube groupLong-term outcomesAcute respiratory distressLong-term safetyPolyurethane-cuffed endotracheal tubePolyurethane cuffA Randomized Controlled Trial of Intrathecal 1% Chloroprocaine Versus 0.75% Hyperbaric Bupivacaine for Short Obstetric Procedures
Togioka B, Tekkali P, Ye S, Rakshe S, Yanez D, Treggiari M. A Randomized Controlled Trial of Intrathecal 1% Chloroprocaine Versus 0.75% Hyperbaric Bupivacaine for Short Obstetric Procedures. Cureus 2025, 17: e97173. PMID: 41426866, PMCID: PMC12714325, DOI: 10.7759/cureus.97173.Peer-Reviewed Original ResearchConceptsExternal cephalic versionTransvaginal cerclage placementPostpartum bilateral tubal ligationCephalic versionBilateral tubal ligationDuration of motor blockCerclage placementTubal ligation surgeryObstetric proceduresBladder catheterizationRandomized Controlled TrialsDischarge readinessKnee flexionMotor blockTubal ligationLigation surgeryHyperbaric bupivacaineMethods Single-centerPostanesthesia care unit dischargePrimary endpointSecondary endpointsSingle-centerSpinal anesthesiaIntrathecal bupivacaineSpinal failureEarly Use of Cryoprecipitate Versus Plasma and Clinical Outcomes in Major Spine Surgery
Depuru A, La J, Treggiari M, Guinn N. Early Use of Cryoprecipitate Versus Plasma and Clinical Outcomes in Major Spine Surgery. Journal Of Clinical Medicine 2025, 14: 7441. PMID: 41156308, PMCID: PMC12564965, DOI: 10.3390/jcm14207441.Peer-Reviewed Original ResearchConceptsPacked red blood cellsTotal blood productsSpine surgeryCryoprecipitate groupOne-year mortalityBlood productsICU-LOSLength of stayBlood lossPostoperative dayH-LOSHospital lengthICU lengthMajor spine surgeryBlood product transfusionHospital length of stayICU length of stayTreatment of coagulopathyRetrospective cohort studyAssociated with higher oddsDischarged to homeProduct transfusionAdult patientsClinical outcomesRed blood cellsAssociation of appropriate empiric antimicrobial therapy with acute kidney injury in gram-negative sepsis.
Ohnuma T, Khandelwal S, Chihara S, Treggiari M, Privratsky J, Wongsripuemtet P, Messina J, Raghunathan K, Krishnamoorthy V. Association of appropriate empiric antimicrobial therapy with acute kidney injury in gram-negative sepsis. Journal Of The Intensive Care Society 2025, 17511437251377990. PMID: 41078621, PMCID: PMC12510998, DOI: 10.1177/17511437251377990.Peer-Reviewed Original ResearchAltmetricConceptsEmpirical antibiotic therapyAcute kidney injuryDevelopment of acute kidney injuryEarly onset sepsisEmpirical antimicrobial therapyAntibiotic therapyGram-negative sepsisOnset sepsisAntimicrobial susceptibilityAntimicrobial therapyRetrospective studyKidney injuryAntimicrobial susceptibility of pathogensGram-negative bloodstream infectionsPrevalence of acute kidney injuryRisk of acute kidney injuryAssociated with in-hospital mortalityUrine output dataBloodstream infection episodesGlobal Outcomes criteriaSerum creatinine levelsGram negative sepsisSusceptibility of pathogensOnset of sepsisPremier Healthcare DatabaseAssociation of Preinjury Beta-Blocker Exposure With Brain Injury Biomarkers Following Traumatic Brain Injury.
Wongsripuemtet P, Ohnuma T, Temkin N, Barber J, Komisarow J, Manley G, Hatfield J, Treggiari M, Colton K, Sasannejad C, Chaikittisilpa N, Grandhi R, Laskowitz D, Mathew J, Hernandez A, James M, Raghunathan K, Miller J, Vavilala M, Krishnamoorthy V. Association of Preinjury Beta-Blocker Exposure With Brain Injury Biomarkers Following Traumatic Brain Injury. Journal Of Neurosurgical Anesthesiology 2025 PMID: 41024341, DOI: 10.1097/ana.0000000000001063.Peer-Reviewed Original ResearchConceptsBeta-blocker exposureBrain injury biomarkersBiomarker levelsBeta-blockersInjury biomarkersTraumatic brain injuryModerate/severe TBIBeta-blocker useBeta-blocker utilizationInverse probability-weighted modelsBrain injuryTransforming clinical researchClinical outcomesHospital mortalityModerate/severe groupPrimary outcomeDay 1Secondary outcomesDay 3Traumatic brain injury severityGlasgow Outcome Scale-ExtendedPreinjuryBiomarkersClinical researchInjuryHypotension prediction index smart alerts and trends to improve compliance with goal-directed hemodynamic therapy: a feasibility study
Guerra-Londono C, Hand W, Fleming N, Davis J, Treggiari M, Dunkman W, Kumar S, Khanna A, Yang J, Domino K. Hypotension prediction index smart alerts and trends to improve compliance with goal-directed hemodynamic therapy: a feasibility study. BMC Anesthesiology 2025, 25: 471. PMID: 41029588, PMCID: PMC12482379, DOI: 10.1186/s12871-025-03336-z.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsNoncardiac surgeryHigh-risk non-cardiac surgeryGoal-directed hemodynamic therapyMethodsThis IRB-approvedIntra-arterial blood pressure monitoringMechanism(s)Non-cardiac surgeryIntra-operative hypotensionElective noncardiac surgeryHypotension Prediction IndexTrial RegistrationThis trialBlood pressure monitoringCompliance rateMinutes of hypotensionHemodynamic therapyRandomized studyLow burdenSmart AlertAdverse outcomesIRB approvalPrimary outcomeHypotensionRegistrationThis trialAlgorithm complianceSurgeryEarly Blood Pressure Targets in Acute Spinal Cord Injury
Sajdeya R, Yanez N, Kampp M, Goodman M, Zonies D, Togioka B, Nunn A, Winfield R, Martin N, Kohli A, Huynh T, Okonkwo D, Poblete R, Gilmore E, Chesnut R, Bunnell A, Ohnuma T, Hashemaghaie M, Treggiari M. Early Blood Pressure Targets in Acute Spinal Cord Injury. JAMA Network Open 2025, 8: e2525364. PMID: 40965887, PMCID: PMC12447234, DOI: 10.1001/jamanetworkopen.2025.25364.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAcute spinal cord injurySpinal cord injuryRandomized clinical trialsConventional blood pressureBlood pressureCord injuryNeurological resuscitationConventional groupEarly blood pressure managementAmerican Spinal Injury Association Impairment Scale scoreSequential Organ Failure Assessment scoreEnd pointsOrgan Failure Assessment scoreClinical trials of patientsRandomized clinical trial of patientsBaseline to 6 monthsMotor scoresPrimary end pointMulticenter Randomized Clinical TrialSafety end pointTrial of patientsMechanical ventilatory supportAugmented blood pressureBlood pressure targetsIntensive care unit dischargeAnesthesiology Clinical Trial Networks in the United States: A Report From the Anesthesia Research Council
Hua M, BillingsIV F, Aziz M, Dutton R, Kheterpal S, Legrand M, Leslie K, Mathew J, McCann M, Subramaniam B, Treggiari M, Wijeysundera D, Gropper M. Anesthesiology Clinical Trial Networks in the United States: A Report From the Anesthesia Research Council. Anesthesia & Analgesia 2025, 141: 522-530. PMID: 40816252, PMCID: PMC12701956, DOI: 10.1213/ane.0000000000007619.Peer-Reviewed Original ResearchConceptsAnesthesiology Clinical Trial Networks in the United States: A Report from the Anesthesia Research Council
Hua M, Billings F, Aziz M, Dutton R, Kheterpal S, Legrand M, Leslie K, Mathew J, McCann M, Subramaniam B, Treggiari M, Wijeysundera D, Gropper M. Anesthesiology Clinical Trial Networks in the United States: A Report from the Anesthesia Research Council. Anesthesiology 2025, 143: 509-517. PMID: 40793804, PMCID: PMC12629501, DOI: 10.1097/aln.0000000000005624.Peer-Reviewed Original ResearchAltmetricConcepts“Service” versus “Education” in Anesthesiology: Domain Classification of Activities Based on Perceptions from Learners and Teachers
Li J, Lin H, Yanez N, He Z, Treggiari M, Kurup V. “Service” versus “Education” in Anesthesiology: Domain Classification of Activities Based on Perceptions from Learners and Teachers. Advances In Medical Education And Practice 2025, 16: 1359-1369. PMID: 40800219, PMCID: PMC12339236, DOI: 10.2147/amep.s527329.Peer-Reviewed Original ResearchCitationsConceptsEducational valuePerceptions of educational valueLearning climateTraining activitiesHigh educational valueClassroom activitiesEducational experienceTeachersLearnersExploratory factor analysisEducationDomains of activityMandatory tasksCompletion ratesMedical educationLearningTraining programFactor analysisQuality of graduate medical educationPerceptionCross-sectional surveyGraduate Medical EducationClassroomAnesthesiology training programsClassification of activities
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