Lavanya Bellumkonda, MD
Associate Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2025
Air Pollution and Exposomic Impacts on Heart Failure.
Bellumkonda L, Khawaja T, Al-Kindi S, Khraishah H, Rajagopalan S. Air Pollution and Exposomic Impacts on Heart Failure. Circulation Heart Failure 2025, e013338. PMID: 41347303, DOI: 10.1161/circheartfailure.125.013338.Peer-Reviewed Original ResearchAir pollution exposureLong-term air pollution exposurePollution exposureAir pollutionEnvironmental risk factorsSocial exposomeEnvironmental health threatsUnderserved populationsHealthcare systemModifiable driversEpidemiological evidenceHeart failureLife courseAir pollution risksBehavioral exposureRisk factorsClinical frameworkPractice strategiesPollution riskCardiovascular morbidityMitigation interventionsPollutionHealth threatRiskCardiovascular impactLoop Diuretic Dose Intensification versus Adjuvant Thiazide for Diuretic Resistance in Acute Heart Failure: Mechanistic Randomized Controlled Trial.
Rao V, Cox Z, Ivey-Miranda J, Moreno-Villagomez J, Ramos-Mastache D, Maulion C, Bellumkonda L, Turner J, Wilson F, Shilpak M, Estrella M, Welling P, Wilcox C, Ellison D, Forbush B, Testani J. Loop Diuretic Dose Intensification versus Adjuvant Thiazide for Diuretic Resistance in Acute Heart Failure: Mechanistic Randomized Controlled Trial. Journal Of The American Society Of Nephrology 2025 PMID: 40938670, DOI: 10.1681/asn.0000000887.Peer-Reviewed Original ResearchFractional excretion of lithiumDose intensificationDiuretic resistanceDiuretic responseFractional excretionHeart failurePrimary outcomeResistance mechanismsLoop diuretic resistanceAcute heart failureExcretion of lithiumLoop of HenleDiuretic strategyRandomized Controlled TrialsSite of actionPrimary trial outcomeOptimal therapyThiazideScreening visitNatriuresisControlled TrialsPatientsInduced increaseExploratory analysisTherapySCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women.
Baron S, Chou J, Shah T, Vest A, Abbott J, Alasnag M, Aurigemma C, Barbato E, Bellumkonda L, Bortnick A, Chieffo A, van Geuns R, Grines C, Halvorsen S, Hassager C, Kapur N, Naidu S, Ng V, Saw J, Lansky A. SCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women. EuroIntervention 2025, 21: 894-909. PMID: 40387531, PMCID: PMC12337771, DOI: 10.4244/eij-d-24-01126.Peer-Reviewed Original ResearchWomen's cardiovascular healthCardiogenic shockConsensus statementSex-based disparitiesCardiovascular healthExpert consensus statementCardiovascular disease statesTreatment of CSCardiovascular diseaseTreatment of womenWomenPoor outcomeDisparitiesDisease statesCS treatmentTreatmentPracticeHealthCliniciansLongitudinal Trends of Coronary Calcifications and Myocardial Flow Reserve in Heart Transplant Recipients
Wright C, Kiage J, Kyriakoulis I, Csecs I, Ahmed A, Liu Y, Bellumkonda L, Kokkinidis D, Sinusas A, Miller E, Feher A. Longitudinal Trends of Coronary Calcifications and Myocardial Flow Reserve in Heart Transplant Recipients. Journal Of Nuclear Cardiology 2025, 50: 102312. DOI: 10.1016/j.nuclcard.2025.102312.Peer-Reviewed Original ResearchWealth and Mortality in the United States and Europe.
Bellumkonda L. Wealth and Mortality in the United States and Europe. The New England Journal Of Medicine 2025, 393: 206. PMID: 40632967, DOI: 10.1056/nejmc2506058.Peer-Reviewed Original ResearchDiagnosis and management of cardiogenic shock
Bellumkonda L. Diagnosis and management of cardiogenic shock. Current Opinion In Critical Care 2025, 31: 428-436. PMID: 40552838, DOI: 10.1097/mcc.0000000000001288.Peer-Reviewed Original ResearchCardiogenic shockLong-term outcomes of patientsOutcomes of patientsMultidisciplinary team-based approachLong-term outcomesManagement of cardiogenic shockAcute myocardial infarctionOverall prognosisStages of shockInfluence prognosisAggressive managementPoor prognosisRisk stratificationImprove mortalityTreatment strategiesTeam-based approachPhenotypic presentationMyocardial infarctionPrognosisClinical practiceEscalate careDisease processEarly identificationRefining interventionsPatients71987 | Readmission Reduction in the Structural Heart Population Using Risk Stratification and Targeted Interventions
Todice M, Forrest J, Bellumkonda L, Workiewicz A, Levesque L, McManus S. 71987 | Readmission Reduction in the Structural Heart Population Using Risk Stratification and Targeted Interventions. Structural Heart 2025, 9: 100518. DOI: 10.1016/j.shj.2025.100518.Peer-Reviewed Original ResearchSCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women This statement was endorsed by the Heart Failure Society of America (HFSA)
Baron S, Chou J, Shah T, Vest A, Abbott J, Alasnag M, Aurigemma C, Barbato E, Bellumkonda L, Bortnick A, Chieffo A, van Geuns R, Grines C, Halvorsen S, Hassager C, Kapur N, Naidu S, Ng V, Saw J, Lansky A. SCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women This statement was endorsed by the Heart Failure Society of America (HFSA). Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102150. PMID: 40630254, PMCID: PMC12230466, DOI: 10.1016/j.jscai.2024.102150.Peer-Reviewed Original ResearchHeart Failure Society of AmericaCardiogenic shockWomen's cardiovascular healthConsensus statementSex-based disparitiesExpert consensus statementCardiovascular healthCardiovascular disease statesTreatment of CSTreatment of womenCardiovascular diseasePoor outcomeWomenDisparitiesSociety of AmericaDisease statesCS treatmentTreatmentPracticeHealthCliniciansPractical Guide on the Use of Induction Immunosuppression in Heart Transplantation
Nikolova A, Bellumkonda L, Bhardwaj A, Fida N, Holzhauser L, Umapathi P, De Marco T, Contreras J. Practical Guide on the Use of Induction Immunosuppression in Heart Transplantation. Circulation Heart Failure 2025, 18: e012382. PMID: 40371476, DOI: 10.1161/circheartfailure.124.012382.Peer-Reviewed Original ResearchInduction immunosuppressionHeart transplantationImpact of induction immunosuppressionHepatitis C positivityRenal protective strategiesRisk stratification modelAt-risk patientsInduction therapyInduction regimensCirculatory death donorsMalignant complicationsMechanical circulatory devicesPerioperative periodImmunomodulatory effectsRecipient riskImmunosuppressionDeath donorsStratification modelTransplantationTherapyPatientsCirculatory devicesAt-riskInductionRIGHT AND LEFT VENTRICULAR REMODELING AFTER ATRIAL SEPTAL DEFECT CLOSURE
Saleh A, Bellumkonda L, Rizzo M, Heller D, Francese D, Tirziu D, Lansky A, Sugeng L, Karnik R. RIGHT AND LEFT VENTRICULAR REMODELING AFTER ATRIAL SEPTAL DEFECT CLOSURE. Journal Of The American College Of Cardiology 2025, 85: 759. DOI: 10.1016/s0735-1097(25)01243-4.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Randomized Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
HIC ID2000028335RolePrincipal InvestigatorPrimary Completion Date01/27/2025Recruiting ParticipantsGenderBothAge18+ yearsErtugliflozin in Acute Heart Failure
HIC ID2000027951RoleSub InvestigatorPrimary Completion Date01/31/2022Recruiting ParticipantsGenderBothAge18+ yearsTranscatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation (APOLLO)
HIC ID2000021883RoleSub InvestigatorPrimary Completion Date10/31/2021Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
Clinical Care
Overview
As a cardiologist who specializes in advanced heart failure and transplantation, Lavanya Bellumkonda, MD, says offering hope is key when she first meets a patient.
“When someone hears the term ‘heart failure,’ they may think they are dying imminently. I first review the severity of their disease and try to set realistic expectations. A number of patients with heart failure will have improvement in their cardiac function with appropriate medical therapy,” she explains. “If their disease is advanced, they may need a mechanical pump to assist the heart or a heart transplantation, and we discuss the success rates and risks associated with each of these strategies.”
Heart failure describes any kind of dysfunction in the heart that causes a build-up of fluids, resulting in shortness of breath, fatigue, and swelling in the legs. Dr. Bellumkonda says she was drawn to her field because of her fascination with the physiology of the heart and the acuity of cardiac illnesses.
“What I also like about transplant cardiology is that you get to apply all that you learnt in medicine and cardiology,” she says. “Post-transplant, patients often rely on me to manage their medical conditions as well.”
Additionally, Dr. Bellumkonda treats patients with valve disease. “The most common valves affected are the mitral or aortic valves, where these valves get either too tight or too leaky, causing symptoms similar to heart failure,” she says. “At Yale, we treat these patients in a multidisciplinary fashion and provide appropriate recommendations regarding catheter-based interventions and surgery.”
Her research interests include cardiac recovery and cardio-renal reactions in patients with valve disease. “What makes me most happy in my work is when I have cardiac recovery in my patients, meaning they have an improvement in their heart function,” she says. “That makes me feel like I have done my job.”
Clinical Specialties
Fact Sheets
Ventricular Assist Device (VAD)
Learn More on Yale MedicineCongestive Heart Failure (CHF)
Learn More on Yale MedicineExtracorporeal Membrane Oxygenation (ECMO)
Learn More on Yale MedicineHeart Failure Surgery
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Cardiovascular Medicine
333 Cedar St., PO Box 20817
New Haven, CT 06520
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