Darrick K. Li, MD, PhD
About
Biography
Darrick Li, MD, PhD is a gastroenterologist at Yale Medicine specializing in the practice of gastroenterology in the inpatient setting. He is dedicated to providing comprehensive and compassionate care of acute conditions involving the gastrointestinal system for patients admitted to the hospital. He treats a variety of conditions including gastrointestinal bleeding, inflammatory bowel disease, removal of foreign bodies, esophageal disorders, diarrheal illnesses, and evaluation and management of nutritional disorders. He is also heavily engaged in the medical education of fellows, residents, and medical students.
He received his M.D. and Ph.D. at the Columbia College of Physicians and Surgeons and completed both his internal medicine residency and his gastroenterology fellowship at Massachusetts General Hospital. During fellowship he performed translational research in non-alcoholic fatty liver disease and hepatitis C as well as clinical research related to evidence-based methodologies and applications.
His primary interests include management of gastrointestinal bleeding, endoscopic hemostatic techniques, clinical education and quality improvement. He is actively involved in research related to anticoagulation management in gastrointestinal bleeding, clinical trials in hospitalized patients with gastrointestinal disease, quality improvement, and systematic reviews of rare gastrointestinal diseases.
Appointments
Digestive Diseases
Assistant Clinical ProfessorPrimary
Other Departments & Organizations
- Digestive Diseases
- Gastroenterology Hospitalist Program
- Internal Medicine
Education & Training
- Clinical and Research Fellow
- Massachusetts General Hospital (2020)
- Chief Resident
- Newton- Wellesley Hospital (2017)
- Resident
- Massachusetts General Hospital (2017)
- PhD
- Columbia College of Physicians and Surgeons, Molecular Biology (2014)
- MD
- Columbia College of Physicians and Surgeons (2014)
- BS
- Yale University, Molecular Biophysics and Biochemistry (2007)
- MS
- Yale University, Molecular Biophysics and Biochemistry (2007)
Board Certifications
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2017
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Dieter Soll, PhD
Kenneth Hung, MD, MS
Loren Laine, MD
Michelle Hughes, MD
Alyssa Ann Grimshaw, MBA, MLIS, MPH
Dhanpat Jain, MD
Publications
2022
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding
Li D, Ong S, Hughes M, Hung K, Agarwal R, Alexis J, Damianos J, Sharma S, Pires J, Nanna M, Laine L. Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding. Alimentary Pharmacology & Therapeutics 2022, 57: 94-102. PMID: 36394111, DOI: 10.1111/apt.17278.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMajor adverse cardiovascular eventsGastrointestinal bleedingPrimary preventionCardiovascular eventsRisk of MACEYale-New Haven HospitalPrimary cardiovascular preventionAdverse cardiovascular eventsKaplan-Meier curvesLong-term outcomesRisk-benefit ratioLog-rank testAspirin 81Hospitalised patientsPrimary endpointSecondary endpointsCardiovascular preventionSubsequent hospitalisationMedian ageDeprescriptionHigh riskAspirinHospitalisationPatientsPreventionEndoscopic Management of Esophageal Cancer.
Dobashi A, Li DK, Mavrogenis G, Visrodia KH, Bazerbachi F. Endoscopic Management of Esophageal Cancer. Thoracic Surgery Clinics 2022, 32: 479-495. PMID: 36266035, DOI: 10.1016/j.thorsurg.2022.07.005.Peer-Reviewed Original ResearchInhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury.
Li DK, Chaudhari SN, Lee Y, Sojoodi M, Adhikari AA, Zukerberg L, Shroff S, Barrett SC, Tanabe K, Chung RT, Devlin AS. Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury. Science Advances 2022, 8: eabo2794. PMID: 36026454, PMCID: PMC9417178, DOI: 10.1126/sciadv.abo2794.Peer-Reviewed Original ResearchLow-Volume Bowel Preparation Is Associated With Reduced Time to Colonoscopy in Hospitalized Patients: A Propensity-Matched Analysis.
Sun CLF, Li DK, Zenteno AC, Bravard MA, Carolan P, Daily B, Elamin S, Ha J, Moore A, Safavi K, Yun BJ, Dunn P, Levi R, Richter JM. Low-Volume Bowel Preparation Is Associated With Reduced Time to Colonoscopy in Hospitalized Patients: A Propensity-Matched Analysis. Clinical And Translational Gastroenterology 2022, 13: e00482. PMID: 35347098, DOI: 10.14309/ctg.0000000000000482.Peer-Reviewed Original ResearchMicroangiopathic Hemolytic Anemia Is a Late and Fatal Complication of Gastric Signet Ring Cell Carcinoma: A Systematic Review and Case-Control Study
Lam R, Tarangelo N, Wang R, Horibe M, Grimshaw AA, Jain D, Haffar S, Bazerbachi F, Kunz PL, Li DK. Microangiopathic Hemolytic Anemia Is a Late and Fatal Complication of Gastric Signet Ring Cell Carcinoma: A Systematic Review and Case-Control Study. The Oncologist 2022, 27: 751-759. PMID: 35589098, PMCID: PMC9438916, DOI: 10.1093/oncolo/oyac093.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsGastric signet ring cell carcinomaSignet ring cell carcinomaMicroangiopathic hemolytic anemiaHemolytic anemiaCell carcinomaMultivariable Cox proportional hazards regression modelingCox proportional hazards regression modelingSystematic reviewRare paraneoplastic syndromeStage-matched casesEnd Results (SEER) databaseLate-stage complicationsRisk of mortalityCase-control studyBone painParaneoplastic syndromeFatal complicationMedian survivalMetastatic diseaseOverall survivalLymph nodesIndex presentationPrognostic featuresResults databasePooled cohort
2021
Adapting to the Challenge of Hospital-Based Care: The Evolving Role of Gastroenterology Hospitalists
Hughes ML, Li DK, Hung KW, Laine L. Adapting to the Challenge of Hospital-Based Care: The Evolving Role of Gastroenterology Hospitalists. The American Journal Of Gastroenterology 2021, 117: 361-363. PMID: 34904965, DOI: 10.14309/ajg.0000000000001585.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricLiver chemistries in glycogenic hepatopathy associated with type 1 diabetes mellitus: A systematic review and pooled analysis.
Haffar S, Izzy M, Habib H, Sugihara T, Li DK, Sharma A, Wang Z, Murad MH, Watt KD, Bazerbachi F. Liver chemistries in glycogenic hepatopathy associated with type 1 diabetes mellitus: A systematic review and pooled analysis. Liver International : Official Journal Of The International Association For The Study Of The Liver 2021, 41: 1545-1555. PMID: 33595181, DOI: 10.1111/liv.14827.Peer-Reviewed Original ResearchVerrucous esophageal carcinoma is a unique indolent subtype of squamous cell carcinoma: a systematic review and individual patient regression analysis.
Li DK, Haffar S, Horibe M, Homsi HA, Zukerberg L, Murad MH, Visrodia KH, Gala M, Katzka DA, Bazerbachi F. Verrucous esophageal carcinoma is a unique indolent subtype of squamous cell carcinoma: a systematic review and individual patient regression analysis. Journal Of Gastroenterology 2021, 56: 12-24. PMID: 33079233, DOI: 10.1007/s00535-020-01736-1.Peer-Reviewed Original Research
2020
Normal liver stiffness and influencing factors in healthy children: An individual participant data meta-analysis.
Li DK, Khan MR, Wang Z, Chongsrisawat V, Swangsak P, Teufel-Schäfer U, Engelmann G, Goldschmidt I, Baumann U, Tokuhara D, Cho Y, Rowland M, Mjelle AB, Ramm GA, Lewindon PJ, Witters P, Cassiman D, Ciuca IM, Prokop LD, Haffar S, Corey KE, Murad MH, Furuya KN, Bazerbachi F. Normal liver stiffness and influencing factors in healthy children: An individual participant data meta-analysis. Liver International : Official Journal Of The International Association For The Study Of The Liver 2020, 40: 2602-2611. PMID: 32901449, DOI: 10.1111/liv.14658.Peer-Reviewed Original Research
2019
Overview of Direct-Acting Antiviral Drugs and Drug Resistance of Hepatitis C Virus.
Li DK, Chung RT. Overview of Direct-Acting Antiviral Drugs and Drug Resistance of Hepatitis C Virus. Methods In Molecular Biology (Clifton, N.J.) 2019, 1911: 3-32. PMID: 30593615, DOI: 10.1007/978-1-4939-8976-8_1.Books
Academic Achievements & Community Involvement
activity American College of Gastroenterology
Professional OrganizationsMemberDetails2018 - Presentactivity American Association for the Study of Liver Diseases
Professional OrganizationsMemberDetails2016 - Presentactivity American Gastroenterological Association
Professional OrganizationsMemberDetails2015 - Presentactivity American Society for Gastrointestinal Endoscopy
Professional OrganizationsMemberDetails2021 - Presentactivity American College of Gastroenterology
Peer Review Groups and Grant Study SectionsCommittee MemberDetailsEducational Affairs Committee07/01/2021 - Present
News
News
- September 09, 2024
The First EHR-Based Machine-Learning Model for GI Bleeding
- August 10, 2023
Ulcerative Colitis: Early Sigmoidoscopy & Clinical Outcomes (Discoveries & Impact August 2023)
- January 08, 2023
Digestive Health Learning Series Back for 2023!
- October 27, 2022Source: Yale Medicine
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Contacts
Yale School of Medicine
Department of Medicine (Digestive Diseases), PO Box 208019
New Haven, Connecticut 06520-8019
United States