2005
Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome
Kalanithi PS, Zheng W, Kataoka Y, DiFiglia M, Grantz H, Saper CB, Schwartz ML, Leckman JF, Vaccarino FM. Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 13307-13312. PMID: 16131542, PMCID: PMC1201574, DOI: 10.1073/pnas.0502624102.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBasal GangliaCaudate NucleusCell CountCell MovementGamma-Aminobutyric AcidGlobus PallidusHumansInterneuronsMiddle AgedNeuronsParvalbuminsTourette SyndromeConceptsTourette syndromeNeuron distributionCalcium-binding protein parvalbuminNeuron numberT subjectsLower neuron numberGlobus pallidus pars externaParvalbumin-positive interneuronsTotal neuron numberUnbiased stereological techniquesChildhood neuropsychiatric disordersBasal ganglia tissueGABAergic neuronsGPi neuronsBasal gangliaCortico-striatoGlobus pallidusProtein parvalbuminThalamic circuitryGanglion tissueVocal ticsNormal controlsPutamen volumePars externaImaging studies
2002
Fibroblast Growth Factor 2 Is Necessary for the Growth of Glutamate Projection Neurons in the Anterior Neocortex
Korada S, Zheng W, Basilico C, Schwartz ML, Vaccarino FM. Fibroblast Growth Factor 2 Is Necessary for the Growth of Glutamate Projection Neurons in the Anterior Neocortex. Journal Of Neuroscience 2002, 22: 863-875. PMID: 11826116, PMCID: PMC6758485, DOI: 10.1523/jneurosci.22-03-00863.2002.Peer-Reviewed Original ResearchConceptsCerebral cortexParietal cortexAnterior cerebral cortexGlutamatergic pyramidal neuronsGABA receptor agonistsGlutamatergic neuronal populationsDuration of sleepAnterior cortical regionsBasic fibroblast growth factorCell numberNull mutant miceGranule cell numberFibroblast growth factor-2Fibroblast growth factorGABA interneuronsGrowth factor 2Fgf2-/- micePyramidal neuronsInhibitory neurotransmissionProjection neuronsAnterior neocortexReceptor agonistPyramidal cellsOccipital cortexNeuronal populations
2000
Differential Modulation of Proliferation in the Neocortical Ventricular and Subventricular Zones
Haydar T, Wang F, Schwartz M, Rakic P. Differential Modulation of Proliferation in the Neocortical Ventricular and Subventricular Zones. Journal Of Neuroscience 2000, 20: 5764-5774. PMID: 10908617, PMCID: PMC3823557, DOI: 10.1523/jneurosci.20-15-05764.2000.Peer-Reviewed Original ResearchMeSH Keywords6-Cyano-7-nitroquinoxaline-2,3-dioneAnimalsAntimetabolitesBromodeoxyuridineCell DifferentiationCell DivisionCell MovementCerebral VentriclesClone CellsExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsFetusGABA AgonistsGABA AntagonistsGamma-Aminobutyric AcidGlutamic AcidKainic AcidMiceMice, Inbred ICRMuscimolNeocortexNeuronsOrgan Culture TechniquesStem CellsConceptsVentricular zoneNeural progenitor populationsNeural progenitor proliferationSubventricular zoneProgenitor populationsCell cycleProgenitor cloneProgenitor proliferationEmbryonic cerebrumNeocortical growthProliferationDifferential responsivenessRecent studiesBromodeoxyuridine uptakeDifferential modulationOrganotypic slice culturesClassical neurotransmitters GABAOpposite effectNeurotransmitter GABARelative contributionClonesDisparate effectsRegulationSlice culturesSpecific GABA
1992
Early Expression of GABA-containing Neurons in the Prefrontal and Visual Cortices of Rhesus Monkeys
Schwartz M, Meinecke D. Early Expression of GABA-containing Neurons in the Prefrontal and Visual Cortices of Rhesus Monkeys. Cerebral Cortex 1992, 2: 16-37. PMID: 1633406, DOI: 10.1093/cercor/2.1.16.Peer-Reviewed Original ResearchConceptsSubplate zoneCortical neuronsRhesus monkeysDensity of GABADistribution of GABAPrimary sensory regionsFirst postnatal weekElectron microscopic immunohistochemistryImmunoreactive neuronsCerebral cortexTransmitter phenotypeCortical maturationCortical plateBipolar neuronsSubventricular zonePostnatal weekCerebral wallCortical neurogenesisVisual cortexMature monkeysVentricular zoneGABASynaptic interactionsDay 41Neurons
1989
GABA-immunoreactive neurons in the mediodorsal nucleus of the monkey thalamus.
Clark A, Schwartz M, Goldman-Rakic P. GABA-immunoreactive neurons in the mediodorsal nucleus of the monkey thalamus. Journal Of Chemical Neuroanatomy 1989, 2: 259-67. PMID: 2803601.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell CountGamma-Aminobutyric AcidImmunohistochemistryMacacaMacaca mulattaThalamic NucleiConceptsGABA-immunoreactive neuronsMediodorsal nucleusParvocellular divisionInhibitory local circuit neuronsPrefrontal cortexLocal circuit organizationLocal circuit neuronsGABA-immunoreactive cellsIntensity of reactivityThalamo-cortical pathwaysGamma-aminobutyric acidCircuit neuronsParvocellular subdivisionMagnocellular neuronsMonkey thalamusBrain circuitryDorsolateral areaNeuronsCircuit organizationIntrinsic organizationThalamusCortexPresent studyFunctional dualityCells
1988
Periodicity of GABA-containing cells in primate prefrontal cortex
Schwartz M, Zheng D, Goldman-Rakic P. Periodicity of GABA-containing cells in primate prefrontal cortex. Journal Of Neuroscience 1988, 8: 1962-1970. PMID: 3385485, PMCID: PMC6569329, DOI: 10.1523/jneurosci.08-06-01962.1988.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFrontal LobeGamma-Aminobutyric AcidImmunochemistryMacaca fascicularisMacaca mulattaNeuronsPeriodicityStatistics as TopicConceptsPrincipal sulcusInhibitory local circuit neuronsLocal circuit neuronsPrimate prefrontal cortexColumns of neuronsCommon physiological propertiesCircuit neuronsGABA cellsImmunoreactive cellsSensory cortexFrontal lobeMacaque monkeysPrefrontal cortexCortexGABATangential distributionNeuronsSulcusCellsPhysiological propertiesCell dispositionAfferentsFindingsFirst indicationGapless series
1986
GABA and GAD immunoreactiviy of photoreceptor terminals in primate retina
Nishimura Y, Schwartz M, Rakic P. GABA and GAD immunoreactiviy of photoreceptor terminals in primate retina. Nature 1986, 320: 753-756. PMID: 3703002, DOI: 10.1038/320753a0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGamma-Aminobutyric AcidGlutamate DecarboxylaseHumansImmune SeraMacacaPhotoreceptor CellsConceptsPhotoreceptor terminalsRhesus monkey retinaFirst-order synapsesGlutamic acid decarboxylasePresynaptic profilesΓ-aminobutyric acidMonkey retinaPerifoveal regionInhibitory neurotransmitterPrimate retinaCone terminalsHorizontal cellsSynaptic functionAcid decarboxylaseRetinaPhotoreceptor cellsVertebrate retinaUltrastructural characteristicsNeurotransmittersAntibodiesSynapsesPresent studyCellsGABAVisual signals
1985
Localization of γ-aminobutyric acid and glutamic acid decarboxylase in rhesus monkey retina
Nishimura Y, Schwartz M, Rakic P. Localization of γ-aminobutyric acid and glutamic acid decarboxylase in rhesus monkey retina. Brain Research 1985, 359: 351-355. PMID: 3907753, DOI: 10.1016/0006-8993(85)91449-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGamma-Aminobutyric AcidGlutamate DecarboxylaseImmunoenzyme TechniquesMacaca mulattaNeuronsRetinaConceptsGlutamic acid decarboxylaseGamma-aminobutyric acidAcid decarboxylaseRhesus monkey retinaGanglion cell layerOuter plexiform layerScleral halfΓ-aminobutyric acidMonkey retinaPlexiform layerUse of antiseraGlial cellsMüller cellsHorizontal cellsRhesus monkeysNeuronal processesReactive bandsSubclass of cellsCell layerImmunoreactive bandsOne-thirdRetinaCellsAmacrineDecarboxylase