2023
Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry)
Tobe A, Sawano M, Kohsaka S, Ishii H, Tanaka A, Numasawa Y, Amano T, Nakamura M, Ikari Y, Murohara T. Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry). The American Journal Of Cardiology 2023, 195: 37-44. PMID: 37004333, DOI: 10.1016/j.amjcard.2023.02.027.Peer-Reviewed Original ResearchConceptsChronic kidney diseasePercutaneous coronary interventionPresence of CKDCKD stages 1Ischemic eventsAdjustment of covariatesHigh riskPCI registryCoronary interventionKidney diseaseNew-generation drug-eluting stent implantationDrug-eluting stent implantationUnderwent Percutaneous Coronary InterventionCKD stage 3Stage 1Bleeding eventsBleeding outcomesDialysis groupOral anticoagulantsCKD 3Renal functionStent implantationIncidence ratePatientsCare delivery
2020
Ischemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment
Shoji S, Sawano M, Sandhu A, Heidenreich P, Shiraishi Y, Ikemura N, Ueno K, Suzuki M, Numasawa Y, Fukuda K, Kohsaka S. Ischemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment. JAMA Network Open 2020, 3: e202004. PMID: 32239221, PMCID: PMC7118520, DOI: 10.1001/jamanetworkopen.2020.2004.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAspirinBrain IschemiaCase-Control StudiesClopidogrelDeathDrug Therapy, CombinationFemaleHemorrhageHumansJapanMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPrasugrel HydrochlorideRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk AssessmentStrokeConceptsLow-dose prasugrelPercutaneous coronary interventionPrimary ischemic eventsAcute coronary syndromeBleeding eventsIschemic eventsCoronary syndromeST-segment elevation myocardial infarctionAcute Coronary Syndrome AssociatedPropensity score-matched analysisHigh-bleeding riskStandard-dose clopidogrelChronic kidney diseaseElevation myocardial infarctionPresent cohort studyShort-term outcomesEast Asian patientsReal-world outcomesPrasugrel treatmentClopidogrel administrationP2Y12 inhibitorsBaseline characteristicsClopidogrel treatmentCohort studyCoronary interventionTransradial Percutaneous Coronary Intervention in Patients With Advanced Chronic Kidney Disease
Yashima F, Inohara T, Numasawa Y, Kuno T, Sawano M, Ueno K, Shimoji K, Noma S, Fukuda K, Kohsaka S. Transradial Percutaneous Coronary Intervention in Patients With Advanced Chronic Kidney Disease. Cardiovascular Revascularization Medicine 2020, 21: 1138-1143. PMID: 32089511, DOI: 10.1016/j.carrev.2020.02.004.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overFemaleFemoral ArteryHumansMalePercutaneous Coronary InterventionRadial ArteryRenal Insufficiency, ChronicRisk FactorsTreatment OutcomeConceptsPercutaneous coronary interventionTransradial interventionTransfemoral interventionAdvanced CKDCKD patientsHemodialysis initiationPCI patientsCoronary interventionPropensity matchingAdvanced chronic kidney diseaseMore procedure-related complicationsChronic kidney disease patientsTransradial percutaneous coronary interventionConsecutive PCI patientsMulticenter Japanese registryAcute kidney injuryChronic kidney diseaseProcedure-related complicationsGlomerular filtration rateKidney disease patientsOutcomes of interestAKI riskKidney injuryClinical outcomesPeriprocedural bleeding
2018
An overview of percutaneous coronary intervention in dialysis patients: Insights from a Japanese nationwide registry
Numasawa Y, Inohara T, Ishii H, Yamaji K, Hirano K, Kohsaka S, Sawano M, Kuno T, Kodaira M, Uemura S, Kadota K, Amano T, Nakamura M, Investigators O. An overview of percutaneous coronary intervention in dialysis patients: Insights from a Japanese nationwide registry. Catheterization And Cardiovascular Interventions 2018, 94: e1-e8. PMID: 30467967, DOI: 10.1002/ccd.27986.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionJapanese nationwide registryDialysis patientsHospital mortalityNondialysis patientsCoronary interventionNationwide registryACS cohortHeart failureAdverse outcomesAcute heart failureMore comorbiditiesCardiogenic shockHospital outcomesBlood transfusionClinical trialsFemale genderPCI casesPatientsJapanese hospitalsGreater riskMortalityComplicationsRegistryRisk
2017
Patterns of statin non-prescription in patients with established coronary artery disease: A report from a contemporary multicenter Japanese PCI registry
Sawano M, Kohsaka S, Abe T, Inohara T, Maekawa Y, Ueda I, Sueyoshi K, Suzuki M, Noma S, Numasawa Y, Miyata H, Fukuda K, Smolderen KG, Spertus JA. Patterns of statin non-prescription in patients with established coronary artery disease: A report from a contemporary multicenter Japanese PCI registry. PLOS ONE 2017, 12: e0182687. PMID: 28817616, PMCID: PMC5560610, DOI: 10.1371/journal.pone.0182687.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCoronary Artery DiseaseDrug PrescriptionsFemaleHospitalsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsJapanMaleMiddle AgedRegistriesRenal Insufficiency, ChronicConceptsChronic kidney diseaseCoronary artery diseasePCI patientsStatin therapyArtery diseaseKidney diseaseHierarchical multivariable logistic regression analysisMultivariable logistic regression analysisPercutaneous coronary intervention registryJapanese PCI registryStatin prescription patternsCoronary Intervention RegistryLow-intensity statinsLogistic regression analysisCardiovascular eventsPCI registryIntervention RegistryPatient characteristicsPrescription patternsReal-world practiceStudy registryEffective medicationsHigh riskPatientsHigher age
2015
Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction
Takei M, Kohsaka S, Shiraishi Y, Goda A, Izumi Y, Yagawa M, Mizuno A, Sawano M, Inohara T, Kohno T, Fukuda K, Yoshikawa T. Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction. Circulation Heart Failure 2015, 8: 527-532. PMID: 25737498, DOI: 10.1161/circheartfailure.114.001734.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdministration, IntravenousAgedAged, 80 and overChi-Square DistributionDisease ProgressionDiuresisDiureticsFemaleHeart FailureHumansIdeal Body WeightKidneyLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPlasma VolumeRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsStroke VolumeTime FactorsTokyoTreatment OutcomeVentricular Function, LeftConceptsPlasma volume reductionAcute heart failureHeart failureRenal functionEjection fractionBody weightWest Tokyo Heart Failure registryAcute heart failure patientsReduced ejection fraction cohortReduced ejection fraction groupEjection fraction groupHeart Failure RegistryReduced ejection fractionHistory of hypertensionGlomerular filtration rateHeart failure patientsIdeal body weightSubject's body weightVolume reductionHFpEF cohortIntravenous diureticsFailure patientsHemodynamic effectsDiabetes mellitusKidney function