2024
A Novel Risk Score for Major Bleeding in Japanese Patients with Non-Valvular Atrial Fibrillation: The J-RISK AF Study
Akao M, Tomita H, Nakai M, Kodani E, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Okamura T, Sasahara Y, Okumura K, Group O. A Novel Risk Score for Major Bleeding in Japanese Patients with Non-Valvular Atrial Fibrillation: The J-RISK AF Study. Journal Of Atherosclerosis And Thrombosis 2024, 31: 1591-1606. PMID: 38811233, PMCID: PMC11537787, DOI: 10.5551/jat.64842.Peer-Reviewed Original ResearchNon-valvular atrial fibrillationOral anticoagulantsRisk stratification systemJapanese patientsHAS-BLEDAtrial fibrillationNon-valvular atrial fibrillation patientsMultivariate Cox proportional hazards analysisConcomitant antiplatelet agentsAF studyCox proportional hazards analysisRisk scoreStratification systemBleeding risk stratificationFollow-up periodNovel risk scoreProportional hazards analysisRisk of ischemic strokeAF RegistryNon-valvularBleeding historyMajor bleedingRisk stratificationAntiplatelet agentsBleeding
2023
Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry)
Tobe A, Sawano M, Kohsaka S, Ishii H, Tanaka A, Numasawa Y, Amano T, Nakamura M, Ikari Y, Murohara T. Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry). The American Journal Of Cardiology 2023, 195: 37-44. PMID: 37004333, DOI: 10.1016/j.amjcard.2023.02.027.Peer-Reviewed Original ResearchConceptsChronic kidney diseasePercutaneous coronary interventionPresence of CKDCKD stages 1Ischemic eventsAdjustment of covariatesHigh riskPCI registryCoronary interventionKidney diseaseNew-generation drug-eluting stent implantationDrug-eluting stent implantationUnderwent Percutaneous Coronary InterventionCKD stage 3Stage 1Bleeding eventsBleeding outcomesDialysis groupOral anticoagulantsCKD 3Renal functionStent implantationIncidence ratePatientsCare delivery
2022
Usefulness of echocardiographic parameters in predicting the incidence of ischemic stroke in Japanese patients with non-valvular atrial fibrillation
Tezuka Y, Akao M, Suzuki S, Yamashita T, Kodani E, Tsuda T, Hayashi K, Furusho H, Sawano M, Fukuda K, Nakai M, Sasahara Y, Miyamoto Y, Tomita H, Okumura K. Usefulness of echocardiographic parameters in predicting the incidence of ischemic stroke in Japanese patients with non-valvular atrial fibrillation. European Heart Journal 2022, 43: ehac544.548. DOI: 10.1093/eurheartj/ehac544.548.Peer-Reviewed Original ResearchIncidence of ISRelative wall thicknessPrescription of OACsCHA2DS2-VASc scoreIschemic strokeLV ejection fractionOral anticoagulantsAtrial fibrillationJapanese patientsNVAF patientsEchocardiographic parametersEjection fractionRisk factorsNon-valvular atrial fibrillation patientsHigher relative wall thicknessNon-valvular atrial fibrillationLV end-diastolic dimensionEcho parametersEnd-diastolic dimensionAtrial fibrillation patientsCo-existing diseasesKaplan-Meier analysisParasternal long-axis viewNovel risk scoreBackground Atrial fibrillationOne-year outcome after percutaneous coronary intervention in nonagenarians: Insights from the J-PCI OUTCOME registry
Otowa K, Kohsaka S, Sawano M, Matsuura S, Chikata A, Maruyama M, Usuda K, Watanabe T, Ishii H, Amano T, Nakamura M, Ikari Y. One-year outcome after percutaneous coronary intervention in nonagenarians: Insights from the J-PCI OUTCOME registry. American Heart Journal 2022, 246: 105-116. PMID: 35016854, DOI: 10.1016/j.ahj.2022.01.004.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAdverse cardiovascular eventsLong-term outcomesCardiovascular eventsNonagenarian patientsCardiovascular mortalityCoronary interventionOutcomes RegistryMajor adverse cardiovascular eventsCV death rateMajor bleeding eventsOne-year outcomesNationwide registration systemPatient-level dataLong-term survivalYears of ageMultivariate regression analysisBleeding eventsCardiogenic shockMajor bleedingOral anticoagulantsAdverse eventsElder patientsCardiac arrestLesion characteristics