2024
Impact of Sex Differences on Clinical Outcomes in Patients Following Primary Revascularization for Acute Myocardial Infarction ― Insights From the Japanese Nationwide Registry ―
Hoshi T, Sawano M, Kohsaka S, Ishii H, Amano T, Takeuchi T, Takahashi J, Hiraya D, Watabe H, Ishizu T, Kozuma K. Impact of Sex Differences on Clinical Outcomes in Patients Following Primary Revascularization for Acute Myocardial Infarction ― Insights From the Japanese Nationwide Registry ―. Circulation Journal 2024, 88: 1211-1222. PMID: 38684394, DOI: 10.1253/circj.cj-23-0966.Peer-Reviewed Original ResearchAcute myocardial infarctionAll-cause mortalityPost-discharge outcomesCrude all-cause mortalityAssociated with all-cause mortalityOne-year all-causeChronic kidney diseaseRates of in-hospital mortalityAcute myocardial infarction patientsPatient-level dataPrevalence of comorbiditiesJapanese Association of Cardiovascular InterventionPost-discharge prognosisAll-causeIn-hospital mortalityNationwide cohortNationwide registriesOutcomes RegistryJ-PCICardiovascular mortalityClinical outcomesSex differencesJapanese nationwide registryRisk profileImpact of sex
2020
Association of Second-Generation Drug-Eluting Stent Length With 2-Year Adverse Clinical Outcomes Among Japanese Patients With Ischemic Heart Disease
Ejiri K, Sawano M, Numasawa Y, Noma S, Ito H, Fukuda K, Kohsaka S. Association of Second-Generation Drug-Eluting Stent Length With 2-Year Adverse Clinical Outcomes Among Japanese Patients With Ischemic Heart Disease. JAMA Network Open 2020, 3: e2012546. PMID: 32756926, PMCID: PMC7407091, DOI: 10.1001/jamanetworkopen.2020.12546.Peer-Reviewed Original ResearchAntithrombotic Strategy for Patients with Acute Coronary Syndrome: A Perspective from East Asia
Numasawa Y, Sawano M, Fukuoka R, Ejiri K, Kuno T, Shoji S, Kohsaka S. Antithrombotic Strategy for Patients with Acute Coronary Syndrome: A Perspective from East Asia. Journal Of Clinical Medicine 2020, 9: 1963. PMID: 32585929, PMCID: PMC7356748, DOI: 10.3390/jcm9061963.Peer-Reviewed Original ResearchAcute coronary syndromeDual antiplatelet therapyComposite ischemic eventsNovel P2Y12 inhibitorsAntithrombotic strategiesP2Y12 inhibitorsCoronary syndromeIschemic eventsWestern patientsTreatment platelet reactivityUse of clopidogrelPercutaneous coronary interventionCurrent clinical guidelinesStandard of careEast Asian patientsBorderline statistical differenceAntiplatelet therapyAntithrombotic therapyCoronary interventionClinical outcomesPlatelet reactivityAsian patientsHemorrhagic diathesisClinical guidelinesClinical studiesAdherence to antihypertensive medication and its predictors among non-elderly adults in Japan
Nishimura S, Kumamaru H, Shoji S, Sawano M, Kohsaka S, Miyata H. Adherence to antihypertensive medication and its predictors among non-elderly adults in Japan. Hypertension Research 2020, 43: 705-714. PMID: 32313192, DOI: 10.1038/s41440-020-0440-2.Peer-Reviewed Original ResearchConceptsLow adherenceAntihypertensive medicationsAntihypertensive drugsJapanese patientsLarge administrative claims databaseAntihypertensive drug usersInitiation of angiotensinAdministrative claims databaseSuboptimal clinical outcomesProportion of daysNon-elderly adultsLogistic regression analysisHypertensive patientsThiazide diureticsClinical outcomesClaims databaseFemale sexHigh adherencePatientsEnzyme inhibitorsDrug usersYounger ageTargeted interventionsFacility characteristicsLarge hospitalsTransradial Percutaneous Coronary Intervention in Patients With Advanced Chronic Kidney Disease
Yashima F, Inohara T, Numasawa Y, Kuno T, Sawano M, Ueno K, Shimoji K, Noma S, Fukuda K, Kohsaka S. Transradial Percutaneous Coronary Intervention in Patients With Advanced Chronic Kidney Disease. Cardiovascular Revascularization Medicine 2020, 21: 1138-1143. PMID: 32089511, DOI: 10.1016/j.carrev.2020.02.004.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransradial interventionTransfemoral interventionAdvanced CKDCKD patientsHemodialysis initiationPCI patientsCoronary interventionPropensity matchingAdvanced chronic kidney diseaseMore procedure-related complicationsChronic kidney disease patientsTransradial percutaneous coronary interventionConsecutive PCI patientsMulticenter Japanese registryAcute kidney injuryChronic kidney diseaseProcedure-related complicationsGlomerular filtration rateKidney disease patientsOutcomes of interestAKI riskKidney injuryClinical outcomesPeriprocedural bleeding
2019
Real-world use of intravascular ultrasound in Japan: a report from contemporary multicenter PCI registry
Kuno T, Numasawa Y, Sawano M, Abe T, Ueda I, Kodaira M, Suzuki M, Noma S, Nakamura I, Negishi K, Ishikawa S, Fukuda K, Kohsaka S. Real-world use of intravascular ultrasound in Japan: a report from contemporary multicenter PCI registry. Heart And Vessels 2019, 34: 1728-1739. PMID: 31129872, DOI: 10.1007/s00380-019-01427-9.Peer-Reviewed Original ResearchConceptsElective percutaneous coronary interventionPercutaneous coronary interventionEmergent percutaneous coronary interventionNon-IVUS groupPCI-related complicationsCoronary dissectionIntravascular ultrasoundIVUS usePCI registryMultivariate logistic regression analysisPlain old balloon angioplastyElective PCI patientsJapanese PCI registryMulticenter PCI registrySevere coronary dissectionMore comorbid conditionsClinical trial dataLogistic regression analysisLow event ratesIVUS groupPCI patientsCoronary interventionConsecutive patientsIndependent predictorsClinical outcomes
2018
Acute heart failure management in the USA and Japan: overview of practice patterns and review of evidence
Tanaka T, Sawano M, Ramani R, Friedman M, Kohsaka S. Acute heart failure management in the USA and Japan: overview of practice patterns and review of evidence. ESC Heart Failure 2018, 5: 931-947. PMID: 29932314, PMCID: PMC6165950, DOI: 10.1002/ehf2.12305.Peer-Reviewed Original ResearchConceptsAcute heart failureTreatment strategiesHeart failureClinical outcomesManagement of AHFAcute heart failure managementOngoing public health issueChronic heart failureHeart failure managementMedical treatment optionsContemporary treatment strategiesEffective treatment strategiesPublic health issueClinical symptomsTreatment optionsPractice patternsSingle agentReview of evidenceFailure managementHealth issuesDefinitive rolePatientsOutcomesFailureSymptoms