2024
Impact of Sex Differences on Clinical Outcomes in Patients Following Primary Revascularization for Acute Myocardial Infarction ― Insights From the Japanese Nationwide Registry ―
Hoshi T, Sawano M, Kohsaka S, Ishii H, Amano T, Takeuchi T, Takahashi J, Hiraya D, Watabe H, Ishizu T, Kozuma K. Impact of Sex Differences on Clinical Outcomes in Patients Following Primary Revascularization for Acute Myocardial Infarction ― Insights From the Japanese Nationwide Registry ―. Circulation Journal 2024, 88: 1211-1222. PMID: 38684394, DOI: 10.1253/circj.cj-23-0966.Peer-Reviewed Original ResearchAcute myocardial infarctionAll-cause mortalityPost-discharge outcomesCrude all-cause mortalityAssociated with all-cause mortalityOne-year all-causeChronic kidney diseaseRates of in-hospital mortalityAcute myocardial infarction patientsPatient-level dataPrevalence of comorbiditiesJapanese Association of Cardiovascular InterventionPost-discharge prognosisAll-causeIn-hospital mortalityNationwide cohortNationwide registriesOutcomes RegistryJ-PCICardiovascular mortalityClinical outcomesSex differencesJapanese nationwide registryRisk profileImpact of sex
2023
Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry)
Tobe A, Sawano M, Kohsaka S, Ishii H, Tanaka A, Numasawa Y, Amano T, Nakamura M, Ikari Y, Murohara T. Ischemic and Bleeding Outcomes in Patients Who Underwent Percutaneous Coronary Intervention With Chronic Kidney Disease or Dialysis (from a Japanese Nationwide Registry). The American Journal Of Cardiology 2023, 195: 37-44. PMID: 37004333, DOI: 10.1016/j.amjcard.2023.02.027.Peer-Reviewed Original ResearchConceptsChronic kidney diseasePercutaneous coronary interventionPresence of CKDCKD stages 1Ischemic eventsAdjustment of covariatesHigh riskPCI registryCoronary interventionKidney diseaseNew-generation drug-eluting stent implantationDrug-eluting stent implantationUnderwent Percutaneous Coronary InterventionCKD stage 3Stage 1Bleeding eventsBleeding outcomesDialysis groupOral anticoagulantsCKD 3Renal functionStent implantationIncidence ratePatientsCare delivery
2022
Overview of in‐hospital outcomes in patients undergoing percutaneous coronary intervention with the revived directional coronary atherectomy
Numasawa Y, Inohara T, Ishii H, Yamaji K, Kohsaka S, Sawano M, Amano T, Nakamura M, Ikari Y, Investigators J. Overview of in‐hospital outcomes in patients undergoing percutaneous coronary intervention with the revived directional coronary atherectomy. Catheterization And Cardiovascular Interventions 2022, 100: 51-58. PMID: 35592940, DOI: 10.1002/ccd.30233.Peer-Reviewed Original ResearchConceptsStable coronary artery diseaseCoronary artery diseaseHospital outcomesUnstable anginaArtery diseaseDCA groupContemporary real-world practiceDrug-coated balloon angioplastyPercutaneous coronary intervention registryHospital adverse outcomesLeft main trunkChronic kidney diseaseDirectional coronary atherectomyPercutaneous coronary interventionCoronary Intervention RegistryLow complication rateTotal contrast volumePreferred treatment strategyPeriprocedural complicationsArtery lesionsBaseline characteristicsComplication rateCoronary atherectomyCoronary interventionIntervention Registry
2021
Evidence‐to‐Practice Gap for Preventing Procedure‐Related Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention
Shoji S, Sawano M, Sandhu A, Heidenreich P, Shiraishi Y, Noma S, Suzuki M, Numasawa Y, Fukuda K, Kohsaka S. Evidence‐to‐Practice Gap for Preventing Procedure‐Related Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention. Journal Of The American Heart Association 2021, 10: e020047. PMID: 34310187, PMCID: PMC8475676, DOI: 10.1161/jaha.120.020047.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overClinical Decision-MakingContrast MediaDatabases, FactualEvidence-Based MedicineFemaleHumansIncidenceJapanKidneyKidney Function TestsMaleMiddle AgedPercutaneous Coronary InterventionProfessional Practice GapsProtective FactorsQuality ImprovementQuality Indicators, Health CareRadiography, InterventionalRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeConceptsAcute kidney injuryPercutaneous coronary interventionAKI risk scoreBaseline renal functionContrast volumeCoronary interventionRisk scoreAKI riskKidney injuryRenal functionAcute coronary syndrome presentationBackground Acute kidney injuryIntra-aortic balloon pumpMultivariable linear regression analysisContrast volume usagePreprocedural risk assessmentChronic kidney diseaseAvailable risk scoresCommon complicationBalloon pumpHeart failureSusceptible patientsOverall incidenceSyndrome presentationKidney disease
2020
Exploring Triaging and Short-Term Outcomes of Early Invasive Strategy in Non-ST Segment Elevation Acute Coronary Syndrome: A Report from Japanese Multicenter Registry
Ikemura N, Shiraishi Y, Sawano M, Ueda I, Numasawa Y, Noma S, Suzuki M, Momiyama Y, Hayashida K, Yuasa S, Miyata H, Fukuda K, Kohsaka S. Exploring Triaging and Short-Term Outcomes of Early Invasive Strategy in Non-ST Segment Elevation Acute Coronary Syndrome: A Report from Japanese Multicenter Registry. Journal Of Clinical Medicine 2020, 9: 1106. PMID: 32294905, PMCID: PMC7230808, DOI: 10.3390/jcm9041106.Peer-Reviewed Original ResearchElevation acute coronary syndromeAcute kidney injuryAcute coronary syndromeHospital mortalityCoronary syndromeMortality riskRisk scoreNon-ST segment elevation acute coronary syndromesNon-ST elevation acute coronary syndromeSegment elevation acute coronary syndromesMultivariable logistic regression analysisJapanese multicenter registryMulticenter Japanese registryEarly invasive strategyChronic kidney diseasePeripheral artery diseaseHospital mortality riskPercutaneous coronary interventionShort-term outcomesRisk-benefit profileLower mortality riskLogistic regression analysisNSTE-ACSKidney injuryMulticenter registryIschemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment
Shoji S, Sawano M, Sandhu A, Heidenreich P, Shiraishi Y, Ikemura N, Ueno K, Suzuki M, Numasawa Y, Fukuda K, Kohsaka S. Ischemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment. JAMA Network Open 2020, 3: e202004. PMID: 32239221, PMCID: PMC7118520, DOI: 10.1001/jamanetworkopen.2020.2004.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAspirinBrain IschemiaCase-Control StudiesClopidogrelDeathDrug Therapy, CombinationFemaleHemorrhageHumansJapanMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPrasugrel HydrochlorideRegistriesRenal Insufficiency, ChronicRetrospective StudiesRisk AssessmentStrokeConceptsLow-dose prasugrelPercutaneous coronary interventionPrimary ischemic eventsAcute coronary syndromeBleeding eventsIschemic eventsCoronary syndromeST-segment elevation myocardial infarctionAcute Coronary Syndrome AssociatedPropensity score-matched analysisHigh-bleeding riskStandard-dose clopidogrelChronic kidney diseaseElevation myocardial infarctionPresent cohort studyShort-term outcomesEast Asian patientsReal-world outcomesPrasugrel treatmentClopidogrel administrationP2Y12 inhibitorsBaseline characteristicsClopidogrel treatmentCohort studyCoronary interventionTransradial Percutaneous Coronary Intervention in Patients With Advanced Chronic Kidney Disease
Yashima F, Inohara T, Numasawa Y, Kuno T, Sawano M, Ueno K, Shimoji K, Noma S, Fukuda K, Kohsaka S. Transradial Percutaneous Coronary Intervention in Patients With Advanced Chronic Kidney Disease. Cardiovascular Revascularization Medicine 2020, 21: 1138-1143. PMID: 32089511, DOI: 10.1016/j.carrev.2020.02.004.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransradial interventionTransfemoral interventionAdvanced CKDCKD patientsHemodialysis initiationPCI patientsCoronary interventionPropensity matchingAdvanced chronic kidney diseaseMore procedure-related complicationsChronic kidney disease patientsTransradial percutaneous coronary interventionConsecutive PCI patientsMulticenter Japanese registryAcute kidney injuryChronic kidney diseaseProcedure-related complicationsGlomerular filtration rateKidney disease patientsOutcomes of interestAKI riskKidney injuryClinical outcomesPeriprocedural bleeding
2019
Comparison of Outcomes After Percutaneous Coronary Intervention in Elderly Patients, Including 10 628 Nonagenarians: Insights From a Japanese Nationwide Registry (J‐PCI Registry)
Numasawa Y, Inohara T, Ishii H, Yamaji K, Kohsaka S, Sawano M, Kodaira M, Uemura S, Kadota K, Amano T, Nakamura M, Kadota K, Shiode N, Tanaka N, Amano T, Uemura S, Akasaka T, Morino Y, Fujii K, Hikichi H, Kohsaka S, Ishii H, Tanabe K, Ozaki Y, Sumitsuji S, Iida O, Hara H, Takashima H, Shirai S, Nanasato M, Inohara T, Ueda Y, Numasawa Y, Noma S. Comparison of Outcomes After Percutaneous Coronary Intervention in Elderly Patients, Including 10 628 Nonagenarians: Insights From a Japanese Nationwide Registry (J‐PCI Registry). Journal Of The American Heart Association 2019, 8: e011183. PMID: 30791799, PMCID: PMC6474917, DOI: 10.1161/jaha.118.011017.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute coronary syndromeOlder patientsHospital mortalityElderly patientsCoronary interventionNationwide registryYounger patientsTransradial interventionStable coronary artery diseaseConclusion Older patientsJapanese nationwide registryProspective nationwide registryChronic kidney diseaseCoronary artery diseaseComparison of outcomesYears of ageCardiac tamponadeCardiogenic shockCoronary syndromeHospital deathHospital outcomesPeriprocedural complicationsArtery diseaseBlood transfusion
2018
Stroke After Percutaneous Coronary Intervention in the Era of Transradial Intervention
Shoji S, Kohsaka S, Kumamaru H, Sawano M, Shiraishi Y, Ueda I, Noma S, Suzuki M, Numasawa Y, Hayashida K, Yuasa S, Miyata H, Fukuda K. Stroke After Percutaneous Coronary Intervention in the Era of Transradial Intervention. Circulation Cardiovascular Interventions 2018, 11: e006761. PMID: 30545258, DOI: 10.1161/circinterventions.118.006761.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionPeriprocedural strokeTransradial interventionTransfemoral interventionCoronary interventionAccess siteElective percutaneous coronary interventionPropensity score-matched analysisMultivariable logistic regression analysisOptimal access siteProspective multicenter databaseAcute kidney injuryAcute coronary syndromeChronic kidney diseaseLife-threatening complicationsPeripheral artery diseaseLogistic regression analysisCoronary syndromeHemorrhagic eventsKidney injuryPCI complicationsArtery diseaseMulticenter databaseStroke patientsKidney disease
2017
Patterns of statin non-prescription in patients with established coronary artery disease: A report from a contemporary multicenter Japanese PCI registry
Sawano M, Kohsaka S, Abe T, Inohara T, Maekawa Y, Ueda I, Sueyoshi K, Suzuki M, Noma S, Numasawa Y, Miyata H, Fukuda K, Smolderen KG, Spertus JA. Patterns of statin non-prescription in patients with established coronary artery disease: A report from a contemporary multicenter Japanese PCI registry. PLOS ONE 2017, 12: e0182687. PMID: 28817616, PMCID: PMC5560610, DOI: 10.1371/journal.pone.0182687.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCoronary artery diseasePCI patientsStatin therapyArtery diseaseKidney diseaseHierarchical multivariable logistic regression analysisMultivariable logistic regression analysisPercutaneous coronary intervention registryJapanese PCI registryStatin prescription patternsCoronary Intervention RegistryLow-intensity statinsLogistic regression analysisCardiovascular eventsPCI registryIntervention RegistryPatient characteristicsPrescription patternsReal-world practiceStudy registryEffective medicationsHigh riskPatientsHigher ageCharacteristics and in-hospital outcomes in young patients presenting with acute coronary syndrome treated by percutaneous coronary intervention
Hirota Y, Sawano M, Numasawa Y, Ueda I, Noma S, Suzuki M, Hayashida K, Yuasa S, Maekawa Y, Kohsaka S, Fukuda K. Characteristics and in-hospital outcomes in young patients presenting with acute coronary syndrome treated by percutaneous coronary intervention. Cardiovascular Intervention And Therapeutics 2017, 33: 154-162. PMID: 28585049, DOI: 10.1007/s12928-017-0471-z.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCoronary artery diseaseMulti-vessel diseaseClassical risk factorsCardiogenic shockYounger patientsACS patientsHospital mortalityCoronary syndromeCulprit lesionRisk factorsFamily historyPremature coronary artery diseaseHigher body mass indexPercutaneous coronary intervention registryConsecutive ACS patientsYoung ACS patientsPrevalence of dyslipidemiaChronic kidney diseasePercutaneous coronary interventionCoronary Intervention RegistryBody mass indexCS presentationLonger life expectancyHospital outcomes