Maternal Fluoxetine Treatment in the Postpartum Period: Effects on Platelet Serotonin and Plasma Drug Levels in Breastfeeding Mother-Infant Pairs
Epperson CN, Jatlow PI, Czarkowski K, Anderson GM. Maternal Fluoxetine Treatment in the Postpartum Period: Effects on Platelet Serotonin and Plasma Drug Levels in Breastfeeding Mother-Infant Pairs. Pediatrics 2003, 112: e425-e425. PMID: 14595087, DOI: 10.1542/peds.112.5.e425.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsMother-infant pairsPlasma drug levelsHigh plasma drug levelsMaternal fluoxetine treatmentBreast milkMeasurement of plateletDrug levelsMonths of ageTransporter blockadePostpartum depressionSSRI exposureFluoxetine treatmentFluoxetine levelsSpecific selective serotonin reuptake inhibitorsSerotonin transporterNeuronal serotonin transporterPostpartum major depressionStudy of sertralineMother's breast milkSerotonin reuptake inhibitorsInfant 4 monthsPlatelet serotonin levelsHuman Investigation CommitteeSubsequent development