2023
A framework for the definition and interpretation of the use of surrogate endpoints in interventional trials
Ciani O, Manyara A, Davies P, Stewart D, Weir C, Young A, Blazeby J, Butcher N, Bujkiewicz S, Chan A, Dawoud D, Offringa M, Ouwens M, Hróbjartssson A, Amstutz A, Bertolaccini L, Bruno V, Devane D, Faria C, Gilbert P, Harris R, Lassere M, Marinelli L, Markham S, Powers J, Rezaei Y, Richert L, Schwendicke F, Tereshchenko L, Thoma A, Turan A, Worrall A, Christensen R, Collins G, Ross J, Taylor R. A framework for the definition and interpretation of the use of surrogate endpoints in interventional trials. EClinicalMedicine 2023, 65: 102283. PMID: 37877001, PMCID: PMC10590868, DOI: 10.1016/j.eclinm.2023.102283.Peer-Reviewed Original ResearchSurrogate endpointsInterventional trialsIntermediate outcomesHealth technology assessment expertsPrimary outcome measureMeasures of functionTreatment effectsE-Delphi studyOutcome measuresConsensus meetingBetter HealthTarget outcomesTrialsEndpointLack of consensusOutcomesPatientsFuture reportingCurrent definitionUrgent needSymptomsCliniciansSettingBiomarkers
2021
To Expand the Evidence Base About Harms from Tests and Treatments
Korenstein D, Harris R, Elshaug AG, Ross JS, Morgan DJ, Cooper RJ, Cho HJ, Segal JB. To Expand the Evidence Base About Harms from Tests and Treatments. Journal Of General Internal Medicine 2021, 36: 2105-2110. PMID: 33479928, PMCID: PMC8298733, DOI: 10.1007/s11606-021-06597-9.Commentaries, Editorials and LettersReporting of harmsAssessment of harmsCare cascadeComorbid illnessesRange of severityTreatment burdenSocial determinantsHealthcare interventionsPatientsEvidence basePsychological distressPhysical impairmentPotential harmTreatmentRigorous evidenceHarmDomains of harmFinancial impactPsychological stateIllnessCliniciansImpairmentSeverityDisruptionDemographics
2015
Physician and other healthcare personnel responses to hospital stroke quality of care performance feedback: a qualitative study
Ross JS, Williams L, Damush TM, Matthias M. Physician and other healthcare personnel responses to hospital stroke quality of care performance feedback: a qualitative study. BMJ Quality & Safety 2015, 25: 441. PMID: 26253122, DOI: 10.1136/bmjqs-2015-004197.Peer-Reviewed Original ResearchConceptsStroke qualityVHA hospitalsCare measuresHealthcare personnelVeterans Health Administration hospitalsStroke care processesPublic reportingQuality improvement effortsAdministration HospitalCare processesHospitalPhysiciansRelevant physiciansHospital administratorsYears of experienceHospital performanceCliniciansNursesQualitative studyInterview transcriptsPersonnel responsesImprovement effortsIdentified areasFeedback initiativeQualitative interviews