2023
Watchman device migration and embolization: A report from the NCDR LAAO Registry
Friedman D, Freeman J, Zimmerman S, Tan Z, Pereira L, Faridi K, Curtis J. Watchman device migration and embolization: A report from the NCDR LAAO Registry. Journal Of Cardiovascular Electrophysiology 2023, 34: 1192-1195. PMID: 37078339, PMCID: PMC10290479, DOI: 10.1111/jce.15909.Peer-Reviewed Original ResearchConceptsWATCHMAN procedureSurgical retrievalDevice migrationMortality rateAtrial appendage closure deviceHospital mortality rateAnnual procedure volumeCardiac surgeryHospital eventsPostdischarge eventsOstial sizeDevice embolizationTaller patientsRetrospective analysisClosure deviceLAA ostiumPatientsProcedure volumeHigh mortalitySurgerySubstantial proportionEmbolizationRegistryGreater body massBody mass
2021
Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation
Bourdillon PM, Parzynski CS, Minges KE, Curtis JP, Desai NR. Trends in ICD Implantations and in-Hospital Outcomes After DOJ Investigation. Journal Of Cardiac Failure 2021, 28: 154-160. PMID: 34628015, DOI: 10.1016/j.cardfail.2021.09.010.Peer-Reviewed Original ResearchConceptsHospital adverse eventsHospital outcomesAdverse eventsHeart failureMyocardial infarctionRecent acute myocardial infarctionPlacement of ICDsPrimary prevention ICDsAdverse event ratesRecent myocardial infarctionAcute myocardial infarctionHigh mortality rateICD implantationRecent diagnosisMortality ratePatientsICDInfarctionHospitalOutcomesRapid reductionUse of devicesFailureSpecific reasonsCriteriaPrognosis of Claims‐ Versus Trial‐Based Ischemic and Bleeding Events Beyond 1 Year After Coronary Stenting
Butala NM, Faridi KF, Secemsky EA, Song Y, Curtis J, Gibson CM, Kazi D, Shen C, Yeh RW. Prognosis of Claims‐ Versus Trial‐Based Ischemic and Bleeding Events Beyond 1 Year After Coronary Stenting. Journal Of The American Heart Association 2021, 10: e018744. PMID: 33682431, PMCID: PMC8174225, DOI: 10.1161/jaha.120.018744.Peer-Reviewed Original ResearchConceptsUnadjusted mortality ratesIschemic eventsDAPT studyMortality rateEnd pointCox proportional hazards modelPercutaneous coronary interventionProportional hazards modelCardiovascular clinical trialsTrial adjudicationBleeding eventsCathPCI RegistryCoronary interventionCoronary stentingSimilar prognosisPrognostic significanceClinical eventsClinical trialsMedicare claimsAdministrative claimsMortality riskHazards modelPatientsPrognosisDeath
2018
Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999–2014
Goldsweig AM, Wang Y, Forrest JK, Cleman MW, Minges KE, Mangi AA, Aronow HD, Krumholz HM, Curtis JP. Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999–2014. Catheterization And Cardiovascular Interventions 2018, 92: 1104-1115. PMID: 29513365, DOI: 10.1002/ccd.27576.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionVentricular septal ruptureTimely primary PCIMortality ratePrimary PCIPercutaneous repairSeptal ruptureMyocardial infarctionRetrospective cohort studyUnadjusted mortality ratesUnrepaired patientsVSR repairFatal complicationCohort studyAnnual incidenceMedicare feeService beneficiariesPatientsIncidenceStudy periodMortalityHospitalizationInfarctionRepairPCI
2017
Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling.
Dharmarajan K, McNamara RL, Wang Y, Masoudi FA, Ross JS, Spatz EE, Desai NR, de Lemos JA, Fonarow GC, Heidenreich PA, Bhatt DL, Bernheim SM, Slattery LE, Khan YM, Curtis JP. Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling. Annals Of Internal Medicine 2017, 167: 555-564. PMID: 28973634, PMCID: PMC9359429, DOI: 10.7326/m16-2871.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesAcute myocardial infarctionOlder patientsYounger patientsMyocardial infarctionAge groupsHospital risk-standardized mortality ratesRetrospective cohort studyHospital mortality rankingsNational Quality ForumHospital mortalityMedian hospitalHospital outcomesCohort studyACTION RegistryAMI mortalityAmerican CollegeMedicare beneficiariesAMI hospitalizationPatientsMortality rateHospitalQuality ForumHospital ValueHospital profiling
2016
ASSOCIATIONS OF HOSPITAL STRATEGIES AND 30-DAY RISK-STANDARDIZED MORTALITY RATES IN PERCUTANEOUS CORONARY INTERVENTION
Curtis J, Minges K, Herrin J, Desai N, Nallamothu B, Rumsfeld J, Elma M, Chen P, Ting H, Messenger J. ASSOCIATIONS OF HOSPITAL STRATEGIES AND 30-DAY RISK-STANDARDIZED MORTALITY RATES IN PERCUTANEOUS CORONARY INTERVENTION. Journal Of The American College Of Cardiology 2016, 67: 34. DOI: 10.1016/s0735-1097(16)30035-3.Peer-Reviewed Original Research
2015
National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Minges KE, Bikdeli B, Wang Y, Kim N, Curtis JP, Desai MM, Krumholz HM. National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010). The American Journal Of Cardiology 2015, 116: 1436-1442. PMID: 26409636, PMCID: PMC4841688, DOI: 10.1016/j.amjcard.2015.07.068.Peer-Reviewed Original ResearchConceptsHospitalization ratesMortality rateReadmission ratesBlack patientsPrincipal discharge diagnosis codeOlder adultsCause readmission rateHospital mortality rateProportion of patientsRetrospective cohort studyDischarge diagnosis codesSkilled nursing facilitiesNational trendsSignificant racial differencesHigh rateHome health careHospital stayAdults AgedCohort studyMore patientsTherapeutic advancesDiagnosis codesMedicare feeNursing facilitiesSignificant burdenEffect of Hospital Volume on Outcomes of Transcatheter Aortic Valve Implantation
Badheka AO, Patel NJ, Panaich SS, Patel SV, Jhamnani S, Singh V, Pant S, Patel N, Patel N, Arora S, Thakkar B, Manvar S, Dhoble A, Patel A, Savani C, Patel J, Chothani A, Savani GT, Deshmukh A, Grines CL, Curtis J, Mangi AA, Cleman M, Forrest JK. Effect of Hospital Volume on Outcomes of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2015, 116: 587-594. PMID: 26092276, DOI: 10.1016/j.amjcard.2015.05.019.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationLength of stayShorter LOSNationwide Inpatient Sample databaseInhospital mortality rateAortic valve implantationLower hospitalization costsHospital volumeInhospital mortalityComplication rateValve implantationHospitalization costsMortality rateUtilization Project Nationwide Inpatient Sample databaseHigher annual hospital volumeOverall inhospital mortality rateMedian LOSClinical Modification procedure codesMultivariate logistic regression modelAnnual hospital volumeLowest volume quartileLow-volume hospitalsPostprocedural complication rateCost of hospitalizationCross-sectional studyAssessing Hospital Performance for Acute Myocardial Infarction
Samadashvili Z, Hannan EL, Cozzens K, Walford G, Jacobs AK, Berger PB, Holmes DR, Venditti FJ, Curtis J. Assessing Hospital Performance for Acute Myocardial Infarction. Medical Care 2015, 53: 245-252. PMID: 25675402, DOI: 10.1097/mlr.0000000000000305.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesNon-PCI hospitalsPercutaneous coronary interventionAcute myocardial infarctionED transfersMyocardial infarctionMortality rateAcute myocardial infarction patientsMedicaid ServicesEmergency department transfersHospital outlier statusRisk-adjusted hospitalMyocardial infarction patientsQuality of careHospital quality assessmentDepartment transfersCoronary interventionPCI hospitalsInfarction patientsInpatient transfersHospitalDifferent hospitals
2014
Transfer Rates From Nonprocedure Hospitals After Initial Admission and Outcomes Among Elderly Patients With Acute Myocardial Infarction
Barreto-Filho JA, Wang Y, Rathore SS, Spatz ES, Ross JS, Curtis JP, Nallamothu BK, Normand SL, Krumholz HM. Transfer Rates From Nonprocedure Hospitals After Initial Admission and Outcomes Among Elderly Patients With Acute Myocardial Infarction. JAMA Internal Medicine 2014, 174: 213-222. PMID: 24296747, DOI: 10.1001/jamainternmed.2013.11944.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCoronary artery bypass graft surgeryArtery bypass graft surgeryRisk-standardized mortality ratesBypass graft surgeryPercutaneous coronary interventionLength of stayMyocardial infarctionElderly patientsGraft surgeryRevascularization ratesCoronary interventionMortality rateLower risk-standardized mortality ratesRate of catheterizationHospital transfer ratesInvasive cardiac proceduresTransfer of patientsRisk-standardized mortalityHospital outcomesInitial admissionMedian lengthService patientsCardiac proceduresHospital differences
2013
Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ≥75 Years of Age
Hannan EL, Zhong Y, Berger PB, Walford G, Curtis JP, Wu C, Venditti FJ, Higgins RS, Smith CR, Lahey SJ, King SB. Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ≥75 Years of Age. The American Journal Of Cardiology 2013, 113: 803-808. PMID: 24440331, DOI: 10.1016/j.amjcard.2013.11.035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overComorbidityComparative Effectiveness ResearchCoronary Artery BypassCoronary Artery DiseaseCoronary StenosisCreatinineDiabetic AngiopathiesDrug-Eluting StentsFemaleHumansKaplan-Meier EstimateMalePercutaneous Coronary InterventionPropensity ScorePulmonary Disease, Chronic ObstructiveRegistriesRetreatmentRisk FactorsTreatment OutcomeConceptsPercutaneous coronary interventionDrug-eluting stentsMortality rateRevascularization ratesMultiple patient risk factorsRepeat revascularization rateCoronary artery bypassMultivessel coronary diseaseIntermediate-term outcomesPatient risk factorsYears of ageArtery bypassCoronary interventionOlder patientsCoronary diseaseRisk factorsObservational studySimilar mortalityPatientsCABGOutcomesStentsYearsBypassMortality
2012
Development of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention
Curtis JP, Geary LL, Wang Y, Chen J, Drye EE, Grosso LM, Spertus JA, Rumsfeld JS, Weintraub WS, Masoudi FA, Brindis RG, Krumholz HM. Development of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention. Circulation Cardiovascular Quality And Outcomes 2012, 5: 628-637. PMID: 22949491, DOI: 10.1161/circoutcomes.111.964569.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAngina PectorisChi-Square DistributionComorbidityFemaleHeart DiseasesHospital MortalityHospitalsHumansLogistic ModelsMaleMyocardial InfarctionOdds RatioOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionQuality Indicators, Health CareRegistriesRisk AssessmentRisk FactorsShock, CardiogenicTime FactorsTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionPercutaneous coronary interventionRisk-standardized mortality ratesElevation myocardial infarctionPatient mortality ratesMyocardial infarctionMortality rateCardiogenic shockCoronary interventionDerivation cohortHospital risk-standardized mortality ratesCause mortality ratesAdministrative claims dataQuality of careHierarchical logistic regression modelsNational Quality ForumLogistic regression modelsObserved mortality rateCathPCI RegistryNational HospitalClaims dataInfarctionPatientsQuality ForumFinal modelHospital strategies for reducing risk-standardized mortality rates in acute myocardial infarction.
Bradley EH, Curry LA, Spatz ES, Herrin J, Cherlin EJ, Curtis JP, Thompson JW, Ting HH, Wang Y, Krumholz HM. Hospital strategies for reducing risk-standardized mortality rates in acute myocardial infarction. Annals Of Internal Medicine 2012, 156: 618-26. PMID: 22547471, PMCID: PMC3386642, DOI: 10.7326/0003-4819-156-9-201205010-00003.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesAcute myocardial infarctionLower risk-standardized mortality ratesMyocardial infarctionNurse championsMortality rateHospital strategiesHospital risk-standardized mortality ratesHospital-level factorsIntensive care unitAcute care hospitalsCardiac catheterization laboratoryCross-sectional surveyUnited Health FoundationCare hospitalCare unitCross-sectional designAMI casesAMI volumeCatheterization laboratoryHospital cliniciansHospitalMultivariate analysisPatientsHealth Foundation
2010
Differences in Patient Survival After Acute Myocardial Infarction by Hospital Capability of Performing Percutaneous Coronary Intervention: Implications for Regionalization
Chen J, Krumholz HM, Wang Y, Curtis JP, Rathore SS, Ross JS, Normand SL, Schreiner GC, Mulvey G, Nallamothu BK. Differences in Patient Survival After Acute Myocardial Infarction by Hospital Capability of Performing Percutaneous Coronary Intervention: Implications for Regionalization. JAMA Internal Medicine 2010, 170: 433-439. PMID: 20212179, PMCID: PMC2900156, DOI: 10.1001/archinternmed.2009.538.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesNon-PCI hospitalsPercutaneous coronary interventionAcute myocardial infarctionHospital referral regionsPCI hospitalsHealth care regionCoronary interventionAMI patientsMyocardial infarctionCare regionLower risk-standardized mortality ratesSame hospital referral regionService beneficiaries 65 yearsBeneficiaries 65 yearsMagnitude of benefitPatient survivalAMI careReferral regionsOutcome differencesMedicare feeMortality rateHospitalHospital capabilitiesInfarctionDEVELOPMENT OF TWO REGISTRY-BASED MEASURES SUITABLE FOR CHARACTERIZING HOSPITAL PERFORMANCE ON 30-DAY ALL-CAUSE MORTALITY RATES AMONG PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
Curtis J, Geary L, Wang Y, Chen J, Drye E, Grosso L, Schreiner G, Spertus J, Rumsfeld J, Weintraub W, Normand S, Krumholz H. DEVELOPMENT OF TWO REGISTRY-BASED MEASURES SUITABLE FOR CHARACTERIZING HOSPITAL PERFORMANCE ON 30-DAY ALL-CAUSE MORTALITY RATES AMONG PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION. Journal Of The American College Of Cardiology 2010, 55: a197.e1852. DOI: 10.1016/s0735-1097(10)61853-0.Peer-Reviewed Original Research
2009
All-Cause Readmission and Repeat Revascularization After Percutaneous Coronary Intervention in a Cohort of Medicare Patients
Curtis JP, Schreiner G, Wang Y, Chen J, Spertus JA, Rumsfeld JS, Brindis RG, Krumholz HM. All-Cause Readmission and Repeat Revascularization After Percutaneous Coronary Intervention in a Cohort of Medicare Patients. Journal Of The American College Of Cardiology 2009, 54: 903-907. PMID: 19712799, DOI: 10.1016/j.jacc.2009.04.076.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionReadmission ratesRevascularization proceduresCause readmissionCoronary interventionPCI proceduresMortality rateIndex percutaneous coronary interventionAcute myocardial infarction patientsCause readmission rateIndex PCI procedureMedian readmission rateDays of dischargeRepeat revascularization proceduresMyocardial infarction patientsNon-AMI patientsPCI patientsRepeat revascularizationRevascularization ratesPrimary outcomeInfarction patientsSuch readmissionsMedicare patientsRetrospective analysisReadmissionReduction in Acute Myocardial Infarction Mortality in the United States: Risk-Standardized Mortality Rates From 1995-2006
Krumholz HM, Wang Y, Chen J, Drye EE, Spertus JA, Ross JS, Curtis JP, Nallamothu BK, Lichtman JH, Havranek EP, Masoudi FA, Radford MJ, Han LF, Rapp MT, Straube BM, Normand SL. Reduction in Acute Myocardial Infarction Mortality in the United States: Risk-Standardized Mortality Rates From 1995-2006. JAMA 2009, 302: 767-773. PMID: 19690309, PMCID: PMC3349070, DOI: 10.1001/jama.2009.1178.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesAcute myocardial infarctionShort-term mortality rateMortality rateHospital variationNonfederal acute care hospitalsAcute myocardial infarction mortalityHospital mortality rateDay of admissionRisk standardized mortality ratesAcute care hospitalsMyocardial infarction mortalityHealth care professionalsIndex hospitalizationCare hospitalMyocardial infarctionNational averagePatient levelMedicare patientsObservational studyMedical adviceHospital varianceMAIN OUTCOMECare professionalsPatients
2003
The association of left ventricular ejection fraction, mortality, and cause of death in stable outpatients with heart failure
Curtis JP, Sokol SI, Wang Y, Rathore SS, Ko DT, Jadbabaie F, Portnay EL, Marshalko SJ, Radford MJ, Krumholz HM. The association of left ventricular ejection fraction, mortality, and cause of death in stable outpatients with heart failure. Journal Of The American College Of Cardiology 2003, 42: 736-742. PMID: 12932612, DOI: 10.1016/s0735-1097(03)00789-7.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionHeart failureCause of deathLVEF groupHF patientsMultivariable adjustmentEjection fractionStable outpatientsAssociation of LVEFHigher left ventricular ejection fractionLow left ventricular ejection fractionDigitalis Investigation Group trialHigh LVEF groupStable HF patientsPrognostic importanceAbsolute riskPrognostic indicatorSinus rhythmGroup trialsMortality ratePatientsMortalityDeathOutpatientsAssociation of Serum Digoxin Concentration and Outcomes in Patients With Heart Failure
Rathore SS, Curtis JP, Wang Y, Bristow MR, Krumholz HM. Association of Serum Digoxin Concentration and Outcomes in Patients With Heart Failure. JAMA 2003, 289: 871-878. PMID: 12588271, DOI: 10.1001/jama.289.7.871.Peer-Reviewed Original ResearchConceptsSerum digoxin concentrationHigh serum digoxin concentrationsLeft ventricular ejection fractionVentricular ejection fractionHeart failureMortality rateDIG trialDigoxin therapyEjection fractionDigoxin concentrationsDepressed left ventricular systolic functionDigitalis Investigation Group trialHigher absolute mortality rateLeft ventricular systolic functionOverall mortality benefitVentricular systolic functionCause mortality ratesAbsolute mortality ratesLower mortality rateCause mortalityMultivariable adjustmentMortality benefitSystolic functionClinical outcomesSerum concentrations