2011
Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1
Sordillo JE, Sharma S, Poon A, Lasky-Su J, Belanger K, Milton DK, Bracken MB, Triche EW, Leaderer BP, Gold DR, Litonjua AA. Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1. BMC Medical Genomics 2011, 12: 158. PMID: 22151743, PMCID: PMC3252252, DOI: 10.1186/1471-2350-12-158.Peer-Reviewed Original ResearchConceptsEndotoxin exposureAsthma riskProtective effectRisk of asthmaGenetic polymorphismsChildhood asthma riskChildhood Asthma StudyInnate immune pathwaysInnate immunity pathwaysAsthma StudyAsthmaConclusionOur findingsImmune pathwaysMinor alleleHome allergensImmunity pathwaysEczemaMajor alleleChildrenEndotoxinExposureRiskSignificant interactionPolymorphismACAA1
2005
Polymorphisms in the 5′ region of the CD14 gene are associated with eczema in young children
Litonjua AA, Belanger K, Celedón JC, Milton DK, Bracken MB, Kraft P, Triche EW, Sredl DL, Weiss ST, Leaderer BP, Gold DR. Polymorphisms in the 5′ region of the CD14 gene are associated with eczema in young children. Journal Of Allergy And Clinical Immunology 2005, 115: 1056-1062. PMID: 15867866, DOI: 10.1016/j.jaci.2005.02.006.Peer-Reviewed Original Research
2002
Genetic and Perinatal Risk Factors for Asthma Onset and Severity: A Review and Theoretical Analysis
Bracken MB, Belanger K, Cookson WO, Triche E, Christiani DC, Leaderer BP. Genetic and Perinatal Risk Factors for Asthma Onset and Severity: A Review and Theoretical Analysis. Epidemiologic Reviews 2002, 24: 176-189. PMID: 12762091, DOI: 10.1093/epirev/mxf012.Peer-Reviewed Original Research