2012
Effects of Ambient Pollen Concentrations on Frequency and Severity of Asthma Symptoms Among Asthmatic Children
DellaValle CT, Triche EW, Leaderer BP, Bell ML. Effects of Ambient Pollen Concentrations on Frequency and Severity of Asthma Symptoms Among Asthmatic Children. Epidemiology 2012, 23: 55-63. PMID: 22082997, PMCID: PMC3246281, DOI: 10.1097/ede.0b013e31823b66b8.Peer-Reviewed Original ResearchConceptsShortness of breathRescue medication useAsthma maintenance medicationsMaintenance medicationPersistent coughSensitized childrenChest tightnessNight symptomsAsthmatic childrenMedication usePollen exposureSeverity of asthmaDaily respiratory symptomsWeed pollenLogistic regression analysisLow exposureSeparate logistic regression analysesAsthmatic symptomsRespiratory symptomsDaily symptomsAntibiotic useSymptom outcomesDaily ambientMedicationsAmbient pollen concentrations
2007
Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypes
Pettigrew MM, Gent JF, Zhu Y, Triche EW, Belanger KD, Holford TR, Bracken MB, Leaderer BP. Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypes. BMC Medical Genomics 2007, 8: 15. PMID: 17407567, PMCID: PMC1852548, DOI: 10.1186/1471-2350-8-15.Peer-Reviewed Original ResearchConceptsPersistent coughSurfactant protein ARespiratory symptomsWhite infantsClinician-diagnosed asthmaInfant respiratory symptomsRespiratory symptom frequencyRisk of wheezeCohort of infantsSingle nucleotide polymorphismsMonths of ageQuarterly telephone interviewsLogistic regression modelsRace/ethnicityStudy infantsNewborn infantsSymptom frequencyInfant's birthStandardized questionnaireCoughWheezeAsthmaInfantsTelephone interviewsOlder children
2006
Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma
Pettigrew MM, Gent JF, Zhu Y, Triche EW, Belanger KD, Holford TR, Bracken MB, Leaderer BP. Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma. BMC Medical Genomics 2006, 7: 68. PMID: 16884531, PMCID: PMC1557482, DOI: 10.1186/1471-2350-7-68.Peer-Reviewed Original ResearchConceptsOtitis mediaWhite infantsInfant respiratory symptomsPhysician-diagnosed asthmaCohort of infantsLarger confirmatory studiesSurfactant proteinsInnate immune responseMonths of ageQuarterly telephone interviewsLogistic regression modelsRace/ethnicityRespiratory symptomsCommon infectionsProspective studyImmune responseStudy populationInfant's birthStandardized questionnaireInfantsConclusionThese resultsAsthmaTelephone interviewsConfirmatory studiesWhole blood
2005
Association of Indoor Nitrogen Dioxide Exposure with Respiratory Symptoms in Children with Asthma
Belanger K, Gent JF, Triche EW, Bracken MB, Leaderer BP. Association of Indoor Nitrogen Dioxide Exposure with Respiratory Symptoms in Children with Asthma. American Journal Of Respiratory And Critical Care Medicine 2005, 173: 297-303. PMID: 16254270, PMCID: PMC2662932, DOI: 10.1164/rccm.200408-1123oc.Peer-Reviewed Original ResearchConceptsRespiratory symptomsChest tightnessIndoor nitrogen dioxide exposureDays of wheezeIndoor NO2 exposureLikelihood of wheezeMold/mildewShortness of breathAdverse respiratory effectsNitrogen dioxide exposurePublic health concernAsthma symptomsActive asthmaMaintenance medicationRespiratory effectsAsthmaChronic exposureSymptomsWheezeHealth concernHome interviewsNO2 exposureMedicationsChildrenGas stoves
2004
Association of early‐onset otitis media in infants and exposure to household mould
Pettigrew MM, Gent JF, Triche EW, Belanger KD, Bracken MB, Leaderer BP. Association of early‐onset otitis media in infants and exposure to household mould. Paediatric And Perinatal Epidemiology 2004, 18: 441-447. PMID: 15535820, DOI: 10.1111/j.1365-3016.2004.00596.x.Peer-Reviewed Original ResearchConceptsEarly otitis mediaOtitis mediaMonths of ageHousehold moldInfant respiratory symptomsAcute otitis mediaPhysician-diagnosed asthmaCohort of infantsOtitis media episodesRecurrent otitis mediaEarly onset otitis mediaMonths of lifeQuarterly telephone interviewsRespiratory symptomsCommon infectionsProspective studyPotential confoundersHigh riskInfant's birthStandardised questionnaireTelephone interviewsMonthsAsthmaEarly childhoodFurther studiesExposure to NO2 and Nitrous Acid and Respiratory Symptoms in the First Year of Life
van Strien RT, Gent JF, Belanger K, Triche E, Bracken MB, Leaderer BP. Exposure to NO2 and Nitrous Acid and Respiratory Symptoms in the First Year of Life. Epidemiology 2004, 15: 471-478. PMID: 15232409, DOI: 10.1097/01.ede.0000129511.61698.d8.Peer-Reviewed Original Research
2003
Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma
Gent JF, Triche EW, Holford TR, Belanger K, Bracken MB, Beckett WS, Leaderer BP. Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma. JAMA 2003, 290: 1859-1867. PMID: 14532314, DOI: 10.1001/jama.290.14.1859.Peer-Reviewed Original ResearchConceptsRescue medication useRespiratory symptomsDaily respiratory symptomsMedication useMaintenance medicationLikelihood of wheezeShortness of breathLogistic regression analysisRescue medicationChest tightnessActive asthmaAsthmatic childrenMedication usersRisk factorsAsthmaMedicationsSymptomsMean levelsSubject's motherChildrenRegression analysisAssociationExposureMothersHigh levels
2002
Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma.
Gent JF, Ren P, Belanger K, Triche E, Bracken MB, Holford TR, Leaderer BP. Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma. Environmental Health Perspectives 2002, 110: a781-a786. PMID: 12460818, PMCID: PMC1241132, DOI: 10.1289/ehp.021100781.Peer-Reviewed Original ResearchConceptsPersistent coughRespiratory symptomsDays of wheezeHigh-risk groupFirst yearPotential confounding factorsPoisson regression analysisCFU/m3Infant's first yearMaternal allergyMaternal historyHigh riskCoughWheezeAsthmaParticular fungal genusHousehold moldConfounding factorsInfant's lifeColony-forming unitsSignificant riskSocioeconomic statusCertain housing characteristicsHigh levelsSusceptible population
2000
Model for the Analysis of Binary Time Series of Respiratory Symptoms
Zhang H, Triche E, Leaderer B. Model for the Analysis of Binary Time Series of Respiratory Symptoms. American Journal Of Epidemiology 2000, 151: 1206-1215. PMID: 10905533, DOI: 10.1093/oxfordjournals.aje.a010171.Peer-Reviewed Original ResearchConceptsDuration of symptomsRespiratory symptomsNew episodesStuffy nosePrior historyHistory of allergyDaily respiratory symptomsInfant Health StudyMeteorologic changesHealth StudySymptomsEpidemiologic researchDay careMarital statusIncidenceEnvironmental epidemiologic researchEpisodesMothersDurationSulfate levelsHusband's levelDemographic variablesNoseHigh levelsAllergy