2013
The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder
Viscidi E, Johnson A, Spence S, Buka S, Morrow E, Triche E. The association between epilepsy and autism symptoms and maladaptive behaviors in children with autism spectrum disorder. Autism 2013, 18: 996-1006. PMID: 24165273, PMCID: PMC4002664, DOI: 10.1177/1362361313508027.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderAutism symptomsMaladaptive behaviorsAutism phenotypeHyperactivity symptomsSpectrum disorderMore autism symptomsCo-occurring intellectual disabilitySimons Simplex CollectionEpilepsy groupLower IQGreater impairmentMore irritabilityIntellectual disabilityIQChildrenImportant clinical implicationsClinical implicationsDisordersSymptomsBehaviorImpairmentIrritabilityImplicationsAssociation
2011
Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1
Sordillo JE, Sharma S, Poon A, Lasky-Su J, Belanger K, Milton DK, Bracken MB, Triche EW, Leaderer BP, Gold DR, Litonjua AA. Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1. BMC Medical Genomics 2011, 12: 158. PMID: 22151743, PMCID: PMC3252252, DOI: 10.1186/1471-2350-12-158.Peer-Reviewed Original ResearchConceptsEndotoxin exposureAsthma riskProtective effectRisk of asthmaGenetic polymorphismsChildhood asthma riskChildhood Asthma StudyInnate immune pathwaysInnate immunity pathwaysAsthma StudyAsthmaConclusionOur findingsImmune pathwaysMinor alleleHome allergensImmunity pathwaysEczemaMajor alleleChildrenEndotoxinExposureRiskSignificant interactionPolymorphismACAA1
2009
Household airborne Penicillium associated with peak expiratory flow variability in asthmatic children
Bundy KW, Gent JF, Beckett W, Bracken MB, Belanger K, Triche E, Leaderer BP. Household airborne Penicillium associated with peak expiratory flow variability in asthmatic children. Annals Of Allergy Asthma & Immunology 2009, 103: 26-30. PMID: 19663123, PMCID: PMC2746059, DOI: 10.1016/s1081-1206(10)60139-1.Peer-Reviewed Original ResearchConceptsPeak expiratory flow variabilityExpiratory flow variabilityAsthmatic childrenAirway hyperreactivityPeak expiratory flowYears of ageLogistic regression modelsAsthma prevalencePhysician diagnosisExpiratory flowChildren 6HyperreactivityChildrenAirborne mold concentrationsRegression modelsAgeCommon moldsIndoor fungiExposureMold concentrationsHomeAsthmaAirborne fungiTotal moldPrevalenceSymptoms and Medication Use in Children with Asthma and Traffic-Related Sources of Fine Particle Pollution
Gent JF, Koutrakis P, Belanger K, Triche E, Holford TR, Bracken MB, Leaderer BP. Symptoms and Medication Use in Children with Asthma and Traffic-Related Sources of Fine Particle Pollution. Environmental Health Perspectives 2009, 117: 1168-1174. PMID: 19654929, PMCID: PMC2717146, DOI: 10.1289/ehp.0800335.Peer-Reviewed Original ResearchConceptsMedication useInhaler useLikelihood of wheezeExacerbation of asthmaMeasures logistic regression modelsRisk of symptomsRespiratory health effectsYears of ageHealth outcomes riskLikelihood of symptomsLogistic regression modelsAsthma 4Outcome riskAsthmaHealth outcomesDaily exposureSymptomsHealth effectsStudy diariesParticle exposureHealth impactsChildrenPublic healthExposureRegression models
2005
Association of Indoor Nitrogen Dioxide Exposure with Respiratory Symptoms in Children with Asthma
Belanger K, Gent JF, Triche EW, Bracken MB, Leaderer BP. Association of Indoor Nitrogen Dioxide Exposure with Respiratory Symptoms in Children with Asthma. American Journal Of Respiratory And Critical Care Medicine 2005, 173: 297-303. PMID: 16254270, PMCID: PMC2662932, DOI: 10.1164/rccm.200408-1123oc.Peer-Reviewed Original ResearchConceptsRespiratory symptomsChest tightnessIndoor nitrogen dioxide exposureDays of wheezeIndoor NO2 exposureLikelihood of wheezeMold/mildewShortness of breathAdverse respiratory effectsNitrogen dioxide exposurePublic health concernAsthma symptomsActive asthmaMaintenance medicationRespiratory effectsAsthmaChronic exposureSymptomsWheezeHealth concernHome interviewsNO2 exposureMedicationsChildrenGas stoves
2003
Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma
Gent JF, Triche EW, Holford TR, Belanger K, Bracken MB, Beckett WS, Leaderer BP. Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma. JAMA 2003, 290: 1859-1867. PMID: 14532314, DOI: 10.1001/jama.290.14.1859.Peer-Reviewed Original ResearchConceptsRescue medication useRespiratory symptomsDaily respiratory symptomsMedication useMaintenance medicationLikelihood of wheezeShortness of breathLogistic regression analysisRescue medicationChest tightnessActive asthmaAsthmatic childrenMedication usersRisk factorsAsthmaMedicationsSymptomsMean levelsSubject's motherChildrenRegression analysisAssociationExposureMothersHigh levels
2001
Risk Factors for Asthma Prevalence Among Urban and Nonurban African American Children
von Maffei J, Beckett W, Belanger K, Triche E, Zhang H, Machung J, Leaderer B. Risk Factors for Asthma Prevalence Among Urban and Nonurban African American Children. Journal Of Asthma 2001, 38: 555-564. PMID: 11714078, DOI: 10.1081/jas-100107120.Peer-Reviewed Original ResearchConceptsRisk factorsUrban residenceAfrican American childrenMaternal cigarette smokingPhysician-diagnosed asthmaMultiple risk factorsYears of ageMaternal asthmaAsthmatic childrenAsthma prevalenceCigarette smokingAsthmaAmerican childrenAfrican American mothersIdentifiable factorsChildrenAmerican mothersResidenceFactorsSmokingAllergyNewbornsPrevalence