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Cary Gross, MD

Professor of Medicine (General Medicine) and of Epidemiology (Chronic Diseases); Member, Yale Cancer Center, Yale University School of Medicine; Member, Center for Outcomes Research and Effectiveness; Founder and Director, Cancer Outcomes Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine; Director, Adult Primary Care Center, Quality Improvement; Chair, National Clinician Scholars Program, National Executive Committee; Director, National Clinician Scholars Program

Contact Information

Cary Gross, MD

Patient Care Location

Office Location

Mailing Address

  • General Internal Medicine

    PO Box 208056, 333 Cedar Street

    New Haven, CT, 06520-8056

    United States

Cary Gross
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Dr. Cary Gross is a Professor of Medicine, and Director of the National Clinician Scholars Program at Yale. Dr. Gross completed his residency in Internal Medicine at New York Hospital-Cornell Medical Center and served as chief medical resident at Memorial Sloan-Kettering Cancer Center the following year.His research addresses comparative effectiveness, quality, and population health, with a focus on cancer prevention and treatment. He is a founding Director of Yale’s Cancer Outcomes Public Policy and Effectiveness Research Center (COPPER). His research has been supported by the National Cancer Institute, the Agency for Healthcare Research and Quality, and the American Cancer Society, among others. As a former Robert Wood Johnson Foundation Clinical Scholar, Dr. Gross has advanced training in biostatistics, epidemiology, research ethics, and outcomes research.

Education & Training

  • MD
    New York University School of Medicine (1993)
  • BA
    Johns Hopkins University (1989)
  • Fellow
    Johns Hopkins School of Medicine
  • Chief Resident
    Memorial Sloan-Kettering Cancer Center
  • Resident
    New York Hospital
  • Intern
    New york Hospital, Cornell Medical Center


  • Geographic Information Systems: Opportunities & Challenges in Cancer Outcomes Research
    Paris, France 2020
  • Understanding Real World Cancer Care and Outcomes: Opportunities for International Collaboration
    Beijing, China 2019
  • Creating and Implementing Clinical Pathways: Where is the Patient Voice?
    San Diego, United States 2019
  • Assessing the Use and Effectiveness of Precision Oncology with Real World Data
    Chicago, United States 2019
  • Innovation & Cancer Care (Panel Discussion)
    New York, United States 2019
  • Contemporary Tumor Registries: What’s Bigger than Big Data?
    Hartford, United States 2019
  • Trends in checkpoint inhibitor therapy for advanced urothelial cell carcinoma (aUC) at the end of life: Insights from real-world practice. Parikh RB, Galsky M, Gyawali B, Riaz F, Kaufmann T, Cohen A, Adamson B, Gross CP, Meropol N, Mamtani R.
    Chicago, United States 2019
  • Contemporary changes in localized and metastatic prostate cancer incidence by geographic area following decreased PSA screening.
    Chicago, United States 2019
  • Chromosome 1 abnormalities and clinical outcomes in multiple myeloma in the era of novel agents. Giri S, Huntington SF, Wang R, Zeidan AM, Podoltsev N, Gore S, Ma X, Gross CP, Davidoff A, Neparidze N.
    Chicago, United States 2019
  • Affordable Care Act (ACA) Medicaid expansion impact of racial disparities in time to cancer treatment. Adamson B, Cohen A, Estevez M, Magee K, Williams E, Gross CP, Meropol N, Davidoff A.
    Chicago, United States 2019
  • Real-world practice patterns and impact of PD-L1 expression testing in patients with advanced non-small cell lung cancer. Leapman M, Presley C, Zhu W, Soulos P, Adelson K, Boffa D, Gross CP.
    Chicago, United States 2019
  • Impact of an oncology urgent care clinic on emergency department rates. Sedghi T, Canavan M, Gross CP, Davidoff A, Gould Rothberg E, Strait M, Sinanis N, Adelson K.
    Chicago, United States 2019
  • Abandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care. Xu, X, Gross, CP.
    Chicago, United States 2019
  • Transforming Cancer Screening and Care in the Modern Era: Time to Pump the Brakes?
    New York, United States 2018
  • The Academic Perspective on Real World Evidence
    Washington, United States 2018
  • Is Sharing Clinical Research Data Ready for Prime Time? Lesson’s Learned from the YODA Project
    Chicago, United States 2018
  • Cancer Screening and Follow-up Care: Too little, Too Much, but Never Too Late
    Chicago, United States 2018
  • Prioritization of patient reported outcomes by women with metastatic breast cancer. Mougalian SS, Aminawung JA, Presley C, Canavan ME, Holland ML, Hu X, Gross CP.
    San Antonio, United States 2018
  • Association between Oncologist Ownership of Imaging Facilities and Utilization: An Analysis of Positron-Emission Tomography (PET) Use in Lymphoma Settings with Variable PET Utility. Huntington SF, Zhu W, Hoag J, Wang R, Zeidan AM, Giri S, Podoltsev NA, Gore SD, Ma X, Gross CP, Davidoff AJ.
    San Diego, United States 2018
  • Persistent use of extended fractionation palliative radiotherapy for Medicare beneficiaries with metastatic breast cancer: 2011-2014. Yu J, Pollack C, Herrin J, Zhu W, Soulos P, Xu X, Gross C.
    San Antonio, United States 2018
  • State breast density inform mandate laws, use of adjunctive tests and cancer detection following screening mammography. Busch S, Hoag J, Aminawung J, Xu X, Richman I, Soulos P, Kyanko K, Gross C.
    Chicago, United States 2018
  • Early Adoption of Digital Breast Tomosynthesis into Clinical Practice: A National Study. Richman I, Hoag J, Forman H, Busch S, Gross C.
    Denver, United States 2018
  • Adoption of New Cancer Screening Modalities in a Privately Insured Population
    Chicago, United States 2017
  • Irrational Exuberance and the Evolution of Cancer Care in the 21st Century
    Baltimore, United States 2017
  • Understanding Conflicts of Interest – Evolution of a Research Agenda. Or: How I Learned to Stop Worrying and Love Big Pharma
    Baltimore, United States 2017
  • Could Social Contagion Help Us Improve Value in Cancer Care & Research?
    Boston, United States 2017
  • Early Insights from an Academic-Industry Collaboration Unlocking Real-World Clinical Data
    Palo Alto, United States 2017
  • Contagious Knowledge: Social Networks, Open Science, & the Effort to Improve Cancer Outcomes
    New York, United States 2017
  • Stereotactic body radiation therapy for oligometastatic disease: a multi-institutional retrospective survival analysis. Bui D, Magnuson W, Lester-Coll N, Qian J, Ross R, Soulos P, Shafman T, Dosoretz A, Evans S, Yu J, Gross C, Decker R.
    San Diego, United States 2017
  • Racial disparities in the use of programmed death 1 checkpoint inhibitors.
    Chicago, United States 2017
  • Disparities in Next Generation Sequencing in a Population-Based Community Cohort of Patients with Advanced Non-Small Cell Lung Cancer. Presley CJ, Soulos PR, Chiang AC, Longtine JA, Adelson KB, Herbst RS, Nussbaum NC, Sorg R, Abernethy AP, Agarwala V, Gross CP.
    Chicago, United States 2017
  • Physician volume and discontinuation of rituximab during lymphoma treatment. Huntington SF, Long JB, Hoag JR, Wang R, Zeidan AM, Gore S, Ma X, Gross CP, Davidoff AJ.
    Chicago, United States 2017
  • Socioeconomic disparities in needle biopsy prior to breast cancer surgery across physician referral networks. Killelea BK, Herrin J, Soulos PR, Pollack C, Forman H, Yu J, Xu X, Tannenbaum S, Wang S, Oladele C, and Gross CP.
    San Antonio, United States 2016
  • Modern Radiotherapy for Left–Sided Breast Cancer: An Analysis of Mean Heart Dose within Diverse Practice Settings. Hong J, Gross C, Shafman T, Hu X, Yu J, Ross R, Dosoretz A, Park H, Soulos P, Evans S, Finkelstein S.
    Boston, United States 2016
  • Pt-reported QOL aft SBRT vs. modhypofractionation for clin loc prostate ca. Johnson SB, Soulos PR, Shafman TD, Mantz CA, Dosoretz A, Ross R, Finkelstein SE, Collins SP, Suy S, Brower JV, Ritter MA, King CR, Kupelian PA, Horwitz EM, Pollack A, Abramowitz MC, Hallman MA, Faria S, Gross CP, and Yu JB.
    Boston, United States 2016
  • A biologic effect dose ≥105Gy assoc w improved overall survival stage I non-sm cell lung ca patients treated with stereotactic body radiation therapy. Stahl JM, Ross R, Harder EM, Mancini BR, Soulos PR, Dosoretz AP, Finkelstein SE, Shafman TD, Husain ZA, Evans SB, Yu JB, Gross CP, and Decker RH.
    Boston, United States 2016
  • Examining Trends in the CMS Medicare Provider Utilization and Payment Database for Radiation Oncologists. Jairam V, Gross C, Yu J.
    Boston, United States 2016
  • Bone density screening in postmenopausal females with early stage breast cancer on aromatase inhibitors. Stratton J, Hu X, Soulos PR, Davidoff AJ, Pusztai L, Gross CP, Mougalian S.
    Chicago, United States 2016
  • Associations of pre- and post-cancer depression with end-of-life cancer care intensity. Doan K, Levy BR, Gross CP, Wang S.
    Chicago, United States 2016
  • Open Science, Transparency, & Data Sharing
    Washington, United States 2015
  • Yale Open Data Access Project: Overview and Lessons Learned
    London, United Kingdom 2015
  • The Quest for Value in Cancer Care and Research in the US and the UK
    London, United Kingdom 2015
  • Improving Cancer Outcomes: Can Researchers be Change Agents?
    Chicago, United States 2014
  • Does Adoption of New Technology Improve Cancer Outcomes?
    London, United Kingdom 2014
  • Improving Cancer Outcomes with Big Data
    London, United Kingdom 2014
  • Improving Cancer Outcomes: Is Research the Problem or the Solution
    London, United Kingdom 2014
  • Improving Cancer Outcomes: Is Research the Problem or the Solution
    London, United Kingdom 2014
  • Improving Cancer Outcomes: Is Research the Solution or the Problem
    San Diego, United States 2014
  • Embracing Complexity: Integrating Multimorbidity into the Cancer Disparities Research Framework
    Atlanta, United States 2013
  • Integrating value into the care of older persons with cancer: Rational decisions or rationing care?
    Farmington, United States 2013
  • The Impact of Age and Comorbidity on Cancer Screening
    New York, United States 2012
  • Introducing National Private Insurance Claims Data for Research
    Washington, United States 2012
  • White Coats, Grass Roots, and Health Reform (Panel Speaker)
    Atlanta, United States 2011
  • Understanding Cancer Screening and Outcomes in an Aging Population
    London, United Kingdom 2011
  • Understanding Comorbidity and Cancer
    Chicago, United States 2010
  • Underrepresentation of Older Persons in Clinical Trials: Implications for Comparative Effectiveness Research
    Chicago, United States 2010
  • Conflict of Interest in Clinical Research: An Empirical Overview
    Washington, United States 2009
  • Focusing on the Big Picture: Integrating Chronic Illness Burden into Decisions about Cancer Screening and Treatment
    Boston, United States 2009
  • Care of the Cancer Survivor
    New London, United States 2009
  • Conflict of Interest in Medicine: Is There a Policy Solution?
    New York, United States 2007
  • Conflict of Interest in Clinical Research: An Empirical Overview
    Washington, United States 2007
  • Impact of Third Party Payer Policies on Clinical Trial Enrollment: What does the Evidence Say
    Baltimore, United States 2007
  • Financial Conflict of Interest and Clinical Research: Impact on Scientific Integrity
    Bethesda, United States 2007
  • The Practicing Oncologist-Pharmaceutical Industry Relationship: What are the Ethical Bounds?
    Chicago, United States 2007
  • Multi-morbidity and Cancer Outcomes: An Integrated Approach
    Detroit, United States 2007
  • Conflict of Interest in Clinical Research: Update for 2007
    Bethesda, United States 2007
  • Primary Care of the Diabetic Patient
    Bridgeport, United States 2007
  • Financial Conflict of Interest and Clinical Research: Impact on Scientific Integrity
    Bethesda, United States 2006
  • Conflict of Interest in Clinical Research
    Bethesda, United States 2006
  • Race and Clinical Trial Enrollment: What do the Data Say?
    Washington, United States 2006
  • Cancer in Underserved Populations: Scope of the Problem in Connecticut
    New Haven, United States 2006
  • Financial Conflict of Interest and Clinical Research: Impact on Scientific Integrity
    Bethesda, United States 2005
  • Financial Conflict of Interest and Clinical Research: Beware the Medical Industrial Complex
    Bethesda, United States 2005
  • Genetics in Primary Care: A Challenge for the New Millennium
    New Haven, United States 2005
  • Financial Conflict of Interest and Clinical Research: Where Should We Go From Here?
    New York, United States 2005
  • Financial Conflict of Interest and Medical Research: Beware the Medical Industrial Complex
    New Orleans, United States 2004
  • Industry-Sponsored Research and the New PhRMA Guidelines – A Perspective from an Academic Medical Center
    Pittsburgh, United States 2003
  • Financial Conflict of Interest in Scientific Publication
    Pittsburgh, United States 2003
  • Barriers to Participation in Cancer Research: Insights from National Cancer Institute Enrollment Data
    New York, United States 2003
  • Financial Conflict of Interest and Medical Research: Beware the Medical Industrial Complex
    Washington, United States 2003
  • Using Disease Burden to Guide Allocation Decisions: Pros and Cons
    Bethesda, United States 1999

Honors & Recognition

AwardAwarding OrganizationDate
Visiting ProfessorJohns Hopkins School of Medicine2017
Paper of the Year, 2001. Gross CP, Steiner CA, Bass EB, Powe NR. Relation between prepublication release of clinical trial results and the practice of carotid endarterectomy. JAMA. 2000; 284:2886-93Academy for Health Services Research and Health Policy2015
Population Sciences Research PrizeYale Cancer Center2013
Mid-Career Research Mentorship AwardSociety of General Internal Medicine2012
FellowAmerican College of Physicians2010
Connecticut Quality Improvement Partnership Silver Innovation PrizeConnecticut Quality Improvement Partnership2006
Joseph A. Zaccagnino Patient Safety and Clinical Quality AwardYale-New Haven Hospital2006
Paul Beeson Physician Faculty Scholars in Aging Research AwardNational Institute on Aging/ American Federation for Aging Research2004
Ralph I. Horwitz LecturerDepartment of Medicine2004
Clinical Investigator AwardSociety of General Internal Medicine, New England Region2003

Professional Service

American Society for Clinical InvestigationMember2018

Departments & Organizations