2023
Brentuximab vedotin + AVD for newly diagnosed classic Hodgkin lymphoma (cHL): Incidence and management of peripheral neuropathy in a multi-institution cohort.
Bowers J, Anna J, Bair S, Annunzio K, Epperla N, Joy Pullukkara J, Gaballa S, Spinner M, Li S, Messmer M, Nguyen J, Ayers E, Wagner C, Hu B, Di M, Huntington S, Furqan F, Shah N, Chen C, Svoboda J. Brentuximab vedotin + AVD for newly diagnosed classic Hodgkin lymphoma (cHL): Incidence and management of peripheral neuropathy in a multi-institution cohort. Journal Of Clinical Oncology 2023, 41: 7542-7542. DOI: 10.1200/jco.2023.41.16_suppl.7542.Peer-Reviewed Original ResearchProgression-free survivalClassic Hodgkin lymphomaECHELON-1 trialBrentuximab vedotinPeripheral neuropathyNon-trial settingOverall survivalLast followInferior progression-free survivalCox proportional hazards modelExperienced grade 1Grade peripheral neuropathyMulti-institution cohortEffect of discontinuationKaplan-Meier methodAdvanced-stage patientsMultivariable logistic regressionProportional hazards modelHigher initial doseDose holdsCommon toxicitiesMedian followDiscontinuation ratesPerformance statusMedian ageFunctional status and therapy for older adults with diffuse large B‐cell lymphoma in nursing homes: A population‐based study
Di M, Keeney T, Belanger E, Huntington S, Olszewski A, Panagiotou O. Functional status and therapy for older adults with diffuse large B‐cell lymphoma in nursing homes: A population‐based study. Journal Of The American Geriatrics Society 2023, 71: 2239-2249. PMID: 36882865, PMCID: PMC10483014, DOI: 10.1111/jgs.18302.Peer-Reviewed Original ResearchConceptsDiffuse large B-cell lymphomaLarge B-cell lymphomaCommunity-dwelling patientsB-cell lymphomaOverall survivalNH patientsCognitive impairmentOdds ratioEnd Results-Medicare databaseAnthracycline-containing regimensDays of diagnosisPopulation-based studyMultivariable logistic regressionPoor overall survivalConfidence intervalsHigh-risk populationAlternative treatment strategiesNursing home careOlder patientsNH residentsFunctional statusPatient preferencesChemoimmunotherapyTreatment strategiesCell lymphoma
2020
Multiple myeloma (MM) therapy within a Medicare-insured patient population: Role of care setting and oncologist sub-specialization in hematologic malignancies.
Davidoff A, Long J, Huntington S. Multiple myeloma (MM) therapy within a Medicare-insured patient population: Role of care setting and oncologist sub-specialization in hematologic malignancies. Journal Of Clinical Oncology 2020, 38: 38-38. DOI: 10.1200/jco.2020.38.29_suppl.38.Peer-Reviewed Original ResearchLines of therapyCare settingsNon-teaching hospitalsHematologic malignanciesSEER-MedicareContinuous Medicare Parts AMajor cancer sitesMultivariable logistic regressionNew immunomodulatory drugsMultiple myeloma therapyEnd of studyMedicare Part ANCI cancer centersFit patientsCell transplantDiagnosis yearImmunomodulatory drugsTreatment patternsMM diagnosisCancer CenterPatient populationCancer sitesMyeloma therapyAcademic hospitalLower odds
2019
Utilization and Early Discontinuation of First-Line Ibrutinib for Patients with Chronic Lymphocytic Leukemia Treated in the Community Oncology Setting in the United States
Huntington S, Soulos P, Barr P, Jacobs R, Lansigan F, Odejide O, Schwartzberg L, Davidoff A, Gross C. Utilization and Early Discontinuation of First-Line Ibrutinib for Patients with Chronic Lymphocytic Leukemia Treated in the Community Oncology Setting in the United States. Blood 2019, 134: 797. DOI: 10.1182/blood-2019-122054.Peer-Reviewed Original ResearchFirst-line settingChronic lymphocytic leukemiaFlatiron Health databaseECOG performance statusFirst-line treatmentEarly discontinuationMultivariable logistic regressionPerformance statusIbrutinib discontinuationSpeakers bureauClinical trialsCLL diagnosisCLL therapyLymphocytic leukemiaHealth databasesLogistic regressionBruton tyrosine kinase inhibitorsFirst-line ibrutinibUse of ibrutinibWorse performance statusPoor performance statusRetrospective cohort studyCommunity oncology settingClinical decision support toolCommunity oncology practices
2014
The Impact of Marital and Socioeconomic Status on Outcomes of Patients with Acute Promyelocytic Leukemia
Huntington S, Shah N, Epstein A, Loren A. The Impact of Marital and Socioeconomic Status on Outcomes of Patients with Acute Promyelocytic Leukemia. Blood 2014, 124: 1282. DOI: 10.1182/blood.v124.21.1282.1282.Peer-Reviewed Original ResearchAcute promyelocytic leukemiaCurable hematological malignancyOutcomes of patientsArea Health Resource FileLong-term survivalHematological malignanciesSocioeconomic statusMarital statusPatient factorsPromyelocytic leukemiaLong-term overall survivalImproved long-term survivalUninsurance ratesIncurable metastatic diseaseCox regression analysisIndividual patient factorsEnd Results ProgramImportant patient factorsMultivariable logistic regressionAcute medical careTiming of presentationLikelihood of deathSocioeconomic factorsSocial supportSocioeconomic status index