2013
A biogenic amine and a neuropeptide act identically: tyramine signals through calcium in Drosophila tubule stellate cells
Cabrero P, Richmond L, Nitabach M, Davies SA, Dow JA. A biogenic amine and a neuropeptide act identically: tyramine signals through calcium in Drosophila tubule stellate cells. Proceedings Of The Royal Society B 2013, 280: 20122943. PMID: 23446525, PMCID: PMC3619477, DOI: 10.1098/rspb.2012.2943.Peer-Reviewed Original ResearchMeSH KeywordsAequorinAnimalsApoproteinsCalcium SignalingChloridesDrosophila melanogasterDrosophila ProteinsGreen Fluorescent ProteinsInositol 1,4,5-Trisphosphate ReceptorsMalpighian TubulesModels, BiologicalNeuropeptidesPhospholipase C betaProtein EngineeringRecombinant ProteinsTyramineWater-Electrolyte BalanceConceptsTrisphosphate receptor geneCalcium signalsStellate cellsTranslational fusionInsect osmoregulationDistinct tissuesIntracellular calciumMode of actionPhospholipase CIntracellular calcium signalsReceptor geneIndependent mechanismsHalf-maximal activationTyramine-induced increaseUAS controlITPRTyramine actEndocrine controlRenal functionCellsNeuropeptides actPrincipal cellsKininsDrosophilaNorpA
2012
Peptide Neuromodulation in Invertebrate Model Systems
Taghert PH, Nitabach MN. Peptide Neuromodulation in Invertebrate Model Systems. Neuron 2012, 76: 82-97. PMID: 23040808, PMCID: PMC3466441, DOI: 10.1016/j.neuron.2012.08.035.Peer-Reviewed Original ResearchConceptsInvertebrate model systemsGenetic model organism Drosophila melanogasterModel organism Drosophila melanogasterAdaptive animal behaviourModel systemCaenorhabditis elegansDrosophila melanogasterPhysiological processesReproductive behaviorSophisticated behavioral paradigmsPhysiological approachAnimal behaviorCircadian rhythmNeuropeptide modulationMelanogasterElegansInsectsNeural circuitsCircuit functionCrustaceansNematodesMollusksPeptide neuromodulationCentral pattern generationNeuropeptides