2004
Nestin promoter/enhancer directs transgene expression to precursors of adult generated periglomerular neurons
Beech RD, Cleary MA, Treloar HB, Eisch AJ, Harrist AV, Zhong W, Greer CA, Duman RS, Picciotto MR. Nestin promoter/enhancer directs transgene expression to precursors of adult generated periglomerular neurons. The Journal Of Comparative Neurology 2004, 475: 128-141. PMID: 15176089, DOI: 10.1002/cne.20179.Peer-Reviewed Original ResearchConceptsPG neuronsSubventricular zoneGranule cellsOlfactory bulbMajor neurogenic regionsAdult-generated neuronsSVZ precursor cellsTetracycline transactivatorRostral migratory streamOlfactory bulb interneuronsTransgene expressionPeriglomerular neuronsPeriglomerular cellsNestin promoterTyrosine hydroxylaseAdult brainInterneuronal populationsBulb interneuronsNeurogenic regionsMigratory streamNeuronal precursorsNeuronsUnique subsetPromoter/enhancerPrecursor cells
2000
Nicotinic-agonist stimulated 86Rb+ efflux and [3H]epibatidine binding of mice differing in β2 genotype
Marks M, Stitzel J, Grady S, Picciotto M, Changeux J, Collins A. Nicotinic-agonist stimulated 86Rb+ efflux and [3H]epibatidine binding of mice differing in β2 genotype. Neuropharmacology 2000, 39: 2632-2645. PMID: 11044733, DOI: 10.1016/s0028-3908(00)00115-5.Peer-Reviewed Original ResearchConceptsBrain regionsNicotinic acetylcholine receptor functionBeta2 subunitBeta2-containing receptorsAcetylcholine receptor functionHigh-affinity siteBeta2 subunit expressionBinding of mouseCerebral cortexNicotinic responsesMicroM nicotineOlfactory bulbInferior colliculusNicotinic agonistsSubunit expressionReceptor functionLow affinityLow affinity sitesDHbetaEInhibitionMiceStimulationEffluxCytisineNull mutation