2012
Nicotinic Regulation of Energy Homeostasis
Zoli M, Picciotto MR. Nicotinic Regulation of Energy Homeostasis. Nicotine & Tobacco Research 2012, 14: 1270-1290. PMID: 22990212, PMCID: PMC3611985, DOI: 10.1093/ntr/nts159.Peer-Reviewed Original ResearchConceptsEnergy homeostasisCellular targetsPossible molecular targetsPrimary psychoactive substanceCell typesNicotinic acetylcholine receptor subtypesEnergy metabolismAcetylcholine receptor subtypesAbility of nicotineEffects of nicotineRegulation of feedingMolecular targetsFunctional featuresRegulationNicotinic regulationHomeostasisReceptor subtypesNAChR subtypesTobacco smokeBody weightNeuroendocrine systemRecent studiesNicotineMetabolismMammals
2011
FACS purification of immunolabeled cell types from adult rat brain
Guez-Barber D, Fanous S, Harvey BK, Zhang Y, Lehrmann E, Becker KG, Picciotto MR, Hope BT. FACS purification of immunolabeled cell types from adult rat brain. Journal Of Neuroscience Methods 2011, 203: 10-18. PMID: 21911005, PMCID: PMC3221768, DOI: 10.1016/j.jneumeth.2011.08.045.Peer-Reviewed Original ResearchConceptsFluorescence-activated cell sortingCell typesPromoter-driven reporter geneBrain tissueExtracellular proteinsFACS procedureReporter geneFACS purificationRat brainReal-time PCRMolecular analysisSorted cellsCell sortingAdult rat brainTime PCRIntact cell bodiesTransgenic miceMolecular alterationsNeuN antibodyQuantitative assayCell bodiesAvailable antibodiesBrainTissueGenes
2006
Expression of ezrin in glial tubes in the adult subventricular zone and rostral migratory stream
Cleary MA, Uboha N, Picciotto MR, Beech RD. Expression of ezrin in glial tubes in the adult subventricular zone and rostral migratory stream. Neuroscience 2006, 143: 851-861. PMID: 16996217, PMCID: PMC1712626, DOI: 10.1016/j.neuroscience.2006.08.028.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBeta CateninBlotting, WesternBromodeoxyuridineCell MovementCell ProliferationCerebral VentriclesCytoskeletal ProteinsEfferent PathwaysGene ExpressionGlial Fibrillary Acidic ProteinImmunohistochemistryMiceNerve Growth FactorsNeural Cell Adhesion Molecule L1NeurogliaS100 Calcium Binding Protein beta SubunitS100 ProteinsSialic AcidsTubulinConceptsRostral migratory streamTube cellsCell-matrix recognitionExpression of ezrinCell type-specific markersCell-cell interactionsNeural cell adhesion molecule 1Specific cell typesStem cell proliferationSubventricular zoneBi-directional signalsMigratory streamERM proteinsERM familyCellular functionsEarly neuronal markerSignal transductionAdult subventricular zoneCell motilityEzrinCell typesGlial tubesCell membraneNeuronal migrationPrecursor cells
1999
Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation
Lawson N, Zain M, Zibello T, Picciotto M, Nairn A, Berliner N. Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation. Experimental Hematology 1999, 27: 1682-1690. PMID: 10560916, DOI: 10.1016/s0301-472x(99)00108-3.Peer-Reviewed Original ResearchConceptsKinase cascadeCaM kinase cascadeNeutrophil maturationRetinoic acidDependent protein kinase kinase alphaWestern analysisProtein kinase cascadeSpecific gene expressionImmediate early fashionNeutrophil-specific gene expressionTrans retinoic acidNeutrophil progenitor cellsRetinoic acid receptorsNeutrophil functionUninduced cellsGene expressionKinase alphaMyeloid cellsVitamin AAcid receptorsRetinoid signalingCell typesEffect of calciumProgenitor cellsProtein levels