2004
Bidirectional Signaling Links the Abelson Kinases to the Platelet-Derived Growth Factor Receptor
Plattner R, Koleske AJ, Kazlauskas A, Pendergast AM. Bidirectional Signaling Links the Abelson Kinases to the Platelet-Derived Growth Factor Receptor. Molecular And Cellular Biology 2004, 24: 2573-2583. PMID: 14993293, PMCID: PMC355852, DOI: 10.1128/mcb.24.6.2573-2583.2004.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineChemotaxisEnzyme ActivationIn Vitro TechniquesMacromolecular SubstancesMiceNIH 3T3 CellsPhospholipase C gammaPhosphorylationProtein-Tyrosine KinasesProto-Oncogene Proteins c-ablReceptor, Platelet-Derived Growth Factor alphaReceptor, Platelet-Derived Growth Factor betaRecombinant ProteinsSignal TransductionType C PhospholipasesConceptsPDGF beta receptorPlatelet-derived growth factorC-AblPLC-gamma1C-Abl nonreceptor tyrosine kinaseTyrosine kinaseGrowth factor signalsSrc family kinasesC-Abl functionNonreceptor tyrosine kinaseTyrosine kinase activityPlatelet-derived growth factor receptorAbundant phosphoinositideMembrane rufflingInducible complexNonredundant functionsFamily kinasesMembrane proteinsC-gamma1Factor signalsGrowth factor receptorAbelson kinaseKinase activityBiological processesChemotaxis defect
1996
[16] Purification of yeast RNA polymerase II holoenzymes
Koleske AJ, Chao DM, Young RA. [16] Purification of yeast RNA polymerase II holoenzymes. Methods In Enzymology 1996, 273: 176-184. PMID: 8791611, DOI: 10.1016/s0076-6879(96)73018-5.Peer-Reviewed Original ResearchConceptsRNA polymerase II holoenzymeRNA polymerase IIPolymerase IIYeast RNA polymerase II holoenzymeGeneral transcription factors TBPTranscription factors TBPHigh molecular weight complexesMolecular weight complexesTranscriptional regulationTranscription initiationYeast SaccharomycesTranscription studiesHoloenzymeHoloenzyme preparationWeight complexesTranscriptionLow salt bufferExciting cluesLarge formSalt concentrationTFIIBTFIIEAssaysSaccharomycesPurification
1995
Association of an activator with an RNA polymerase II holoenzyme.
Hengartner CJ, Thompson CM, Zhang J, Chao DM, Liao SM, Koleske AJ, Okamura S, Young RA. Association of an activator with an RNA polymerase II holoenzyme. Genes & Development 1995, 9: 897-910. PMID: 7774808, DOI: 10.1101/gad.9.8.897.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceGenes, FungalHerpes Simplex Virus Protein Vmw65Macromolecular SubstancesMediator ComplexModels, GeneticMolecular Sequence DataMutationPrecipitin TestsProtein BindingRestriction MappingRNA Polymerase IISaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Analysis, DNASuppression, GeneticTranscription FactorsTranscription, GeneticConceptsRNA polymerase II holoenzymeRNA polymerase IISRB proteinsPolymerase IIDomain of VP16General transcription factorsDirect interactionTranscription apparatusTranscriptional activatorMediators of activationTranscription initiationTranscription factorsImmunoprecipitation experimentsHoloenzymeGenesActivatorAffinity columnProteinSubcomplexPromoterVP16BindsInteractionHallmarkActivation