2016
Expression of KCNJ1 (ROMK) in the Gastrointestinal Tract
Han J, Lee S, Ishikawa Y, Guo X, Xu S, Wang T. Expression of KCNJ1 (ROMK) in the Gastrointestinal Tract. The FASEB Journal 2016, 30 DOI: 10.1096/fasebj.30.1_supplement.1224.31.Peer-Reviewed Original ResearchROMK expressionDistal colonMRNA expressionKO miceRenal outer medullary potassium channelEpithelial cellsGI tractGastric acid secretionGastrointestinal (GI) tractHK intakeROMK channelsWT miceDistal nephronReal-time PCRApical membraneROMKPotassium channelsAcid secretionParietal cellsIF stainingRenal tubulesQ-PCR dataEsophagusDiet animalsGastrointestinal tract
2010
Mechanotransduction in the renal tubule
Weinbaum S, Duan Y, Satlin LM, Wang T, Weinstein AM. Mechanotransduction in the renal tubule. American Journal Of Physiology. Renal Physiology 2010, 299: f1220-f1236. PMID: 20810611, PMCID: PMC3006307, DOI: 10.1152/ajprenal.00453.2010.Peer-Reviewed Original Research
2009
Functional expression of the olfactory signaling system in the kidney
Pluznick JL, Zou DJ, Zhang X, Yan Q, Rodriguez-Gil DJ, Eisner C, Wells E, Greer CA, Wang T, Firestein S, Schnermann J, Caplan MJ. Functional expression of the olfactory signaling system in the kidney. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 2059-2064. PMID: 19174512, PMCID: PMC2644163, DOI: 10.1073/pnas.0812859106.Peer-Reviewed Original ResearchConceptsGlomerular filtration ratePlasma renin levelsMacula densa cellsCOX-2 expressionRenal distal nephronOlfactory G-proteinMDS cell linesOlfactory receptorsRenin levelsRenin secretionFiltration rateNNOS activityTubuloglomerular feedbackDistal nephronOlfactory epitheliumRenal tubulesGFR regulationAdenylate cyclaseG proteinsCell linesSensory roleKidneyFunctional expressionOlfactionExpression
1990
Time- and dose-dependent effects of protein kinase C on proximal bicarbonate transport
Wang T, Chan Y. Time- and dose-dependent effects of protein kinase C on proximal bicarbonate transport. The Journal Of Membrane Biology 1990, 117: 131-139. PMID: 2120446, DOI: 10.1007/bf01868680.Peer-Reviewed Original ResearchConceptsFluid reabsorptionProtein kinase CDose-dependent effectKinase CDose-response natureOriginal perfusatePerfusion timeΒ-phorbolCapillary perfusionLuminal perfusionPCT transportMaximal effectRenal tubulesBicarbonate absorptionRat kidneyFluid absorptionTotal CO2 changesBrush border membraneBasolateral sideTime-dependent effectsDose responseEIPAAmilorideM PMALuminal side