2010
ROLE OF DOPAMINE IN MODULATING FLOW‐DEPENDENT SODIUM AND BICARBONATE TRANSPORT IN MOUSE PROXIMAL TUBULE
Du Z, Yan Q, Weinbaum S, Weinstein A, Wang T. ROLE OF DOPAMINE IN MODULATING FLOW‐DEPENDENT SODIUM AND BICARBONATE TRANSPORT IN MOUSE PROXIMAL TUBULE. The FASEB Journal 2010, 24: 1024.2-1024.2. DOI: 10.1096/fasebj.24.1_supplement.1024.2.Peer-Reviewed Original ResearchProximal tubule transportEffects of dopamineMouse proximal tubulesTubule transportProximal tubulesNHE3 endocytosisMin/PKA-mediated mechanismRole of dopamineLuminal flow ratePmoles/min/Luminal dopamineKidney proximal tubulesPerfusion rateSodium reabsorptionNet reabsorptionDopamineReabsorptionCAMP-dependent protein kinase inhibitor H89SCH23390SulpirideInhibitor H89TubulesBicarbonate transportHCO-3
1995
Effects of chronic hyperfiltration on proximal tubule bicarbonate transport and cell electrolytes
Ohno A, Beck F, Pfaller W, Giebisch G, Wang T. Effects of chronic hyperfiltration on proximal tubule bicarbonate transport and cell electrolytes. Kidney International 1995, 48: 712-721. PMID: 7474656, DOI: 10.1038/ki.1995.342.Peer-Reviewed Original ResearchConceptsNa/H exchangeProximal tubulesUNX ratsK-ATPase activityBicarbonate absorptionBicarbonate transportChronic hyperfiltrationRemnant kidneyUnilateral nephrectomyFiltration rateCortical tubulesRenal clearanceBicarbonate levelsH secretionFluid absorptionMaximal transport rateBasolateral ion transportCompensatory responseMarked stimulationRubidium uptakeSimilar stimulationCell ion concentrationsBasolateral NaTubulesUNX
1993
Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule.
Wang T, Malnic G, Giebisch G, Chan Y. Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule. Journal Of Clinical Investigation 1993, 91: 2776-2784. PMID: 8390489, PMCID: PMC443344, DOI: 10.1172/jci116519.Peer-Reviewed Original ResearchConceptsLate distal tubuleEarly distal tubuleDistal tubulesBicarbonate absorptionTubule segmentsFluid absorptionBicarbonate transportLuminal bicarbonate concentrationNet bicarbonate transportRenal bicarbonate reabsorptionLow K dietDistal tubule segmentsBicarbonate concentrationK-ATPase inhibitorPmol/minK dietBicarbonate secretionMicroperfusion experimentsBicarbonate reabsorptionH-ATPaseTubulesBafilomycin A1High rateRatsATPase inhibitor