2022
“If it weren’t for my traditional healer, I would be dead”: Engaging traditional healers to support people living with HIV in rural Mozambique
Audet CM, Pettapiece-Phillips M, Tian Y, Shepherd BE, Vermund SH, Salato J. “If it weren’t for my traditional healer, I would be dead”: Engaging traditional healers to support people living with HIV in rural Mozambique. PLOS ONE 2022, 17: e0270565. PMID: 35763519, PMCID: PMC9239464, DOI: 10.1371/journal.pone.0270565.Peer-Reviewed Original ResearchConceptsTraditional healersPsychosocial supportCommunity health worker interventionPre-post intervention study designWorker interventionHealth worker interventionMedication possession ratioMedication side effectsIntervention study designPositive test resultsHome-based supportObserved therapyPossession ratioClinical outcomesHIV treatmentPoor adherencePost-intervention participantsHealth facilitiesPatient's desireSide effectsZambézia ProvinceCare servicesStudy designHIVTherapy
2021
The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico.
Vermund SH, Febo I. The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico. Puerto Rico Health Sciences Journal 2021, 40: 3-5. PMID: 33876911, PMCID: PMC8363137.Peer-Reviewed Original ResearchConceptsHigh background prevalenceElimination of HIVWorld Health OrganizationChildren HIVInfection overallPerinatal transmissionAntenatal servicesBackground prevalenceHIV riskSyphilis transmissionSyphilis therapyHIVHealth OrganizationSyphilisMothersPuerto RicoInfantsTherapyPrevalenceCareEliminationWomen
2018
Exploration of Implementation Patterns and Content from a Text-Based Outreach Intervention Clinical Trial for Newly Diagnosed, HIV-Positive MSM in Beijing, China
Knudson A, Shaw S, Yin L, Xiao D, Qian HZ, Sullivan S, Liu H, Ruan Y, Shao Y, Vermund SH, Amico KR. Exploration of Implementation Patterns and Content from a Text-Based Outreach Intervention Clinical Trial for Newly Diagnosed, HIV-Positive MSM in Beijing, China. AIDS And Behavior 2018, 23: 1158-1165. PMID: 30288683, PMCID: PMC6566097, DOI: 10.1007/s10461-018-2287-y.Peer-Reviewed Original ResearchShifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017
Landis R, Abayomi E, Bain B, Greene E, Janossy G, Joseph P, Kerrigan D, McCoy JP, Nunez C, O'Gorman M, Pastoors A, Parekh B, Quimby K, Quinn TC, Robertson K, Thomas R, van Gorp E, Vermund SH, Wilson V. Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017. AIDS Research And Human Retroviruses 2018, 34: 561-569. PMID: 29732897, PMCID: PMC6053839, DOI: 10.1089/aid.2017.0310.Peer-Reviewed Original ResearchConceptsJoint United Nations ProgrammePublic health benefitsHIV/AIDSPublic health messagingNew medical treatmentsAntiretroviral therapyHIV diseaseUNAIDS 90United Nations ProgrammeMedical treatmentHealth messagingHealth benefitsNations ProgrammeDiseaseInternational expertsCareHealthcare professionsCritical appraisalTreatmentPersistent fearSpirit of optimismStigmaHIVTherapyCommunity level
2017
Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapyThe Continuum of HIV Care in the Urban United States: Black Men Who Have Sex With Men (MSM) Are Less Likely Than White MSM to Receive Antiretroviral Therapy
Vermund SH. The Continuum of HIV Care in the Urban United States: Black Men Who Have Sex With Men (MSM) Are Less Likely Than White MSM to Receive Antiretroviral Therapy. The Journal Of Infectious Diseases 2017, 216: 790-794. PMID: 28368523, PMCID: PMC5853891, DOI: 10.1093/infdis/jix009.Peer-Reviewed Original Research
2014
Assessing spatial patterns of HIV knowledge in rural Mozambique using geographic information systems
Buehler CP, Blevins M, Ossemane EB, González‐Calvo L, Ndatimana E, Vermund SH, Sidat M, Olupona O, Moon TD. Assessing spatial patterns of HIV knowledge in rural Mozambique using geographic information systems. Tropical Medicine And International Health 2014, 20: 353-364. PMID: 25430042, DOI: 10.1111/tmi.12437.Peer-Reviewed Original ResearchConceptsHIV knowledgeAntiretroviral therapyEnumeration areasMedian scorePopulation-based cluster surveyMore HIV knowledgeHIV knowledge scoresMultivariable linear regression modelsLow HIV knowledgePoor HIV knowledgeHIV knowledge levelsDistrict of residenceHealth facilitiesZambézia ProvinceNumber of childrenKnowledge scoreProgram plannersTherapyMore educationLinear regression modelsScoresAssessment toolRural MozambiqueRegression modelsRespondent ageMethadone Maintenance Therapy and HIV Counseling and Testing are Associated with Lower frequency of Risky Behaviors Among Injection Drug Users in China
Wang M, Mao W, Zhang L, Jiang B, Xiao Y, Jia Y, Wu P, Cassell H, Vermund S. Methadone Maintenance Therapy and HIV Counseling and Testing are Associated with Lower frequency of Risky Behaviors Among Injection Drug Users in China. Substance Use & Misuse 2014, 50: 15-23. PMID: 25295376, DOI: 10.3109/10826084.2014.957768.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyInjection drug usersMaintenance therapyDrug usersConsecutive cross-sectional surveysHIV voluntary counselingUnprotected sexual behaviorCross-sectional surveyRisky behaviorsHIV counselingVoluntary counselingNeedle sharingUnprotected sexMMT servicesSignificant associationVCTLast monthSexual behaviorTherapyCounselingChronic Diseases in HIV Survivors
Vermund SH, Narayan KM, Glass RI. Chronic Diseases in HIV Survivors. Science Translational Medicine 2014, 6: 241ed14-241ed14. PMID: 24944191, DOI: 10.1126/scitranslmed.3008684.Peer-Reviewed Original Research
2013
Oral Lesions: Poor Markers of Virologic Failure in HIV-Infected Patients on Antiretroviral Therapy
Tami-Maury I, Willig J, Jolly P, Vermund S, Aban I, Hill J, Wilson C. Oral Lesions: Poor Markers of Virologic Failure in HIV-Infected Patients on Antiretroviral Therapy. ISRN Infectious Diseases 2013, 2013: 1-7. DOI: 10.5402/2013/269728.Peer-Reviewed Original ResearchPositive predictive valueVirologic failureAntiretroviral therapyPredictive valueViral loadHigh baseline viral loadMonths of ARTModerate positive predictive valueBaseline viral loadStrong positive predictive valueNegative predictive valueVirologic statusBaseline factorsCopies/Poor markerPatientsMental disordersOL groupTherapyMonthsHIVArt therapyPoor predictorMarkersFailureHaemoglobin recovery among HIV-1 infected patients on zidovudine-based antiretroviral therapy and other regimens in north-central Nigeria
Parrish DD, Blevins M, Megazzini KM, Shepherd BE, Mohammed MY, Wester CW, Vermund SH, Aliyu MH. Haemoglobin recovery among HIV-1 infected patients on zidovudine-based antiretroviral therapy and other regimens in north-central Nigeria. International Journal Of STD & AIDS 2013, 25: 355-359. PMID: 24104694, PMCID: PMC4385388, DOI: 10.1177/0956462413506887.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnemiaAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveDrug Therapy, CombinationFemaleHemoglobinsHIV InfectionsHumansLinear ModelsMaleMiddle AgedNigeriaRetrospective StudiesReverse Transcriptase InhibitorsRural PopulationSocioeconomic FactorsTime FactorsTreatment OutcomeZidovudineConceptsBaseline hemoglobin levelCombination antiretroviral therapyHemoglobin levelsAntiretroviral therapyHemoglobin recoveryNon-pregnant adult patientsUse of zidovudineZidovudine-containing regimenZidovudine-containing regimensNorth Central NigeriaGroup of patientsRural North-Central NigeriaMeasures of hemoglobinZidovudine useBaseline hemoglobinAdult patientsMedian hemoglobinHemoglobin responseHIV-1PatientsZidovudineHemoglobin dataHemoglobinRegimensTherapy
2012
The HIV Epidemic: High-Income Countries
Vermund SH, Leigh-Brown AJ. The HIV Epidemic: High-Income Countries. Cold Spring Harbor Perspectives In Medicine 2012, 2: a007195. PMID: 22553497, PMCID: PMC3331688, DOI: 10.1101/cshperspect.a007195.Peer-Reviewed Original ResearchConceptsInjection drug useHIV epidemicDrug useNeedle/syringe sharingReceptive anal intercourseDifferent risk groupsRecent explosive epidemicsAntiretroviral therapyChild transmissionSyringe sharingAffected subgroupRisk groupsAnal intercourseVaginal intercourseHIV vulnerabilityExplosive epidemicsDiagnostic screeningEpidemicIncome countriesIntercourseUnited StatesSpecific strainsHigh-income nationsHIVTherapy
2010
An Empirical Approach to Defining Loss to Follow-up Among Patients Enrolled in Antiretroviral Treatment Programs
Chi BH, Cantrell RA, Mwango A, Westfall AO, Mutale W, Limbada M, Mulenga LB, Vermund SH, Stringer JS. An Empirical Approach to Defining Loss to Follow-up Among Patients Enrolled in Antiretroviral Treatment Programs. American Journal Of Epidemiology 2010, 171: 924-931. PMID: 20219765, PMCID: PMC2850972, DOI: 10.1093/aje/kwq008.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV-infected adultsAntiretroviral treatment programLTFU definitionTreatment cohortsPatient attritionLast appointmentPatient lossCohort membersLTFUConsensus criteriaTreatment programPatientsOne-thirdMore reliable comparisonsDaysAppointmentsTherapyCohortCliniciansMisclassificationMarginal differencesVisitsCare
2009
Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges
Wester CW, Bussmann H, Koethe J, Moffat C, Vermund S, Essex M, Marlink RG. Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges. HIV Therapy 2009, 3: 501-526. PMID: 20161344, PMCID: PMC2774911, DOI: 10.2217/hiv.09.35.Peer-Reviewed Original ResearchCombination antiretroviral therapyAntiretroviral therapyUse of cARTFirst-line combination antiretroviral therapyHIV-1-infected adultsPrimary HIV-1 infectionMonths of treatmentHIV-1 infectionResource-rich settingsHigh mortality rateImmunologic recoveryVirologic suppressionHIV infectionHealthcare utilizationSaharan AfricaAdherence ratesLifelong monitoringPROGRESS trialTreatment outcomesMortality rateCART programClinical servicesImpressive declineTherapyInfectionPreventing HIV in Developing Countries: Status of Biomedical Interventions
Vermund S. Preventing HIV in Developing Countries: Status of Biomedical Interventions. The FASEB Journal 2009, 23: 199.1-199.1. DOI: 10.1096/fasebj.23.1_supplement.199.1.Peer-Reviewed Original ResearchHIV Prevention Trials NetworkPrevention of motherHIV drug resistanceNeedle exchange programsDNA boostBehavior changeHIV seroconversionHIV seroincidenceEarly therapyPregnant womenHSV-2Clinical trialsHIVMale circumcisionDrug addiction treatmentDrug resistanceTrials NetworkAddiction treatmentBiomedical interventionsSeroincidenceInfantsRisk reductionTherapyPrevention challengesEfficacy
2004
Antiretroviral therapy in sub-Saharan Africa: adherence lessons from tuberculosis and leprosy
Reid SE, Reid CA, Vermund SH. Antiretroviral therapy in sub-Saharan Africa: adherence lessons from tuberculosis and leprosy. International Journal Of STD & AIDS 2004, 15: 713-716. PMID: 15537453, DOI: 10.1258/0956462042395195.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyInfected personsAntiretroviral treatment programAntiretroviral drug therapyHuman immunodeficiency virusResource-limited settingsAdherence strategiesImmunodeficiency virusSaharan AfricaAdequate adherenceDrug therapyDrug costsLeprosy controlTreatment programTherapyTuberculosisLeprosyAdherenceControl programs
2003
Developing a Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Therapeutic Research Agenda for Resource-Limited Countries: A Consensus Statement
Vermund SH, Powderly WG, Association of IDSA O. Developing a Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Therapeutic Research Agenda for Resource-Limited Countries: A Consensus Statement. Clinical Infectious Diseases 2003, 37: s4-s12. PMID: 12822127, DOI: 10.1086/375367.Peer-Reviewed Original ResearchConceptsResource-limited countriesAntiretroviral therapyResource-limited settingsDelivery of ARTImmunodeficiency syndrome careClinical Trials NetworkHealth care providersResource limited countriesHealth care practitionersHealth care advocatesHIV diseaseHIV/Consensus statementTreatment accessCare providersCare practitionersTrials NetworkART provisionCare advocatesTherapyMillions of peoplePharmaceutical expertsPatient monitoringCommunity representativesDiseaseComparison of Two Strategies for Administering Nevirapine to Prevent Perinatal HIV Transmission in High-Prevalence, Resource-Poor Settings
Stringer JS, Sinkala M, Stout JP, Goldenberg RL, Acosta EP, Chapman V, Kumwenda-Phiri R, Vermund SH. Comparison of Two Strategies for Administering Nevirapine to Prevent Perinatal HIV Transmission in High-Prevalence, Resource-Poor Settings. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2003, 32: 506-513. PMID: 12679702, PMCID: PMC2745994, DOI: 10.1097/00126334-200304150-00007.Peer-Reviewed Original ResearchConceptsHigh-prevalence settingsClinic AClinic BVCT servicesPrevent Perinatal HIV TransmissionPerinatal HIV acquisitionPerinatal HIV preventionPerinatal HIV transmissionKnowledge of serostatusResource-poor settingsNevirapine therapyNVP therapyHIV acquisitionHIV testingHIV statusHIV transmissionPregnant womenCord bloodHIV preventionHigh prevalenceInfant deathUniversal therapyClinicTherapyMaternal reports
2002
Perinatal HIV transmission: developing country considerations
Goldenberg RL, Stringer JS, Sinkala M, Vermund SH. Perinatal HIV transmission: developing country considerations. The Journal Of Maternal-Fetal & Neonatal Medicine 2002, 12: 149-158. PMID: 12530611, DOI: 10.1080/jmf.12.3.149.158.Peer-Reviewed Original ResearchConceptsMaternal HIV infectionMaternal-child transmissionObstetric care systemTransmission of HIVMortality rate 10HIV infectionAntiviral therapyPregnant womenChildhood mortalityInfantsHIVCare systemDevastating problemEarly childhoodInfectionMothersSubstantial additional resourcesTherapyMortalityPrevalenceWomen
2001
Zambian women's attitudes toward mass nevirapine therapy to prevent perinatal transmission of HIV
Sinkala M, Stout J, Vermund S, Goldenberg R, Stringer J. Zambian women's attitudes toward mass nevirapine therapy to prevent perinatal transmission of HIV. The Lancet 2001, 358: 1611-1612. PMID: 11716891, DOI: 10.1016/s0140-6736(01)06662-4.Peer-Reviewed Original Research