2009
Baseline brain energy supports the state of consciousness
Shulman RG, Hyder F, Rothman DL. Baseline brain energy supports the state of consciousness. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 11096-11101. PMID: 19549837, PMCID: PMC2708743, DOI: 10.1073/pnas.0903941106.Peer-Reviewed Original ResearchConceptsLoss of consciousnessBrain energyConscious stateHigh-frequency neuronal activityCerebral energy consumptionBrain energy consumptionCerebral energyEnsembles of neuronsRat brainSomatosensory responsesNeuronal activityGamma-band rangeNeuronal propertiesFiring rateSensory stimulationNeuronal signalingPET measurementsAnesthesiaFMRI patternsFMRI activity patternsOxygen consumptionState of consciousnessStimulationBehavioral abilitiesMagnetic resonance spectroscopy
2008
Neurophysiology of functional imaging
van Eijsden P, Hyder F, Rothman DL, Shulman RG. Neurophysiology of functional imaging. NeuroImage 2008, 45: 1047-1054. PMID: 18801442, PMCID: PMC2677905, DOI: 10.1016/j.neuroimage.2008.08.026.Peer-Reviewed Original ResearchConceptsCognitive psychologyCognitive modularityPsychological conceptsPsychological propertiesCognitive conceptsObjective physical measuresMental lifeMental functionsBrain energyBOLD signalSeparable areasSubjective conceptFMRIDegree of awarenessFunctional imagingEmpirical responsesPsychologySensory functionPhysical measuresStimuliNeurophysiologyBrainAdjectivesOperational termsRevolutionary hopes
2007
A BOLD search for baseline
Shulman RG, Rothman DL, Hyder F. A BOLD search for baseline. NeuroImage 2007, 36: 277-281. PMID: 17223362, PMCID: PMC2684871, DOI: 10.1016/j.neuroimage.2006.11.035.Peer-Reviewed Original Research
2006
Neuronal–Glial Glucose Oxidation and Glutamatergic–GABAergic Function
Hyder F, Patel AB, Gjedde A, Rothman DL, Behar KL, Shulman RG. Neuronal–Glial Glucose Oxidation and Glutamatergic–GABAergic Function. Cerebrovascular And Brain Metabolism Reviews 2006, 26: 865-877. PMID: 16407855, DOI: 10.1038/sj.jcbfm.9600263.Peer-Reviewed Original ResearchConceptsGamma-amino butyric acid (GABA) neuronsNeuronal glucose oxidationGlutamate-glutamine cyclingRelease of lactateGlucose oxidationNeuronal oxidationGlial uptakeGABAergic neuronsGlutamate uptakeGliaNeuronsGlycolytic ATPLactateGlucoseTotal glucoseVivo rateIsoelectricityCulture studiesATPNeurotransmittersUptake