2024
Non-pharmacological Interventions for Muscle Cramps and Pain in Patients With Cirrhosis: A Systematic Review
Muller R, Dranoff J, Grimshaw A, Bastian L, Gunderson C. Non-pharmacological Interventions for Muscle Cramps and Pain in Patients With Cirrhosis: A Systematic Review. Cureus 2024 DOI: 10.7759/cureus.64859.Peer-Reviewed Original Research
2022
The association of depression with mortality and major adverse limb event outcomes in patients with peripheral artery disease: A systematic review and meta-analysis
Scierka LE, Mena-Hurtado C, Ahmed ZV, Yousef S, Arham A, Grimshaw AA, Harris KM, Burg M, Vriens PW, Heyligers J, Lee M, Yazgan I, Smolderen KG. The association of depression with mortality and major adverse limb event outcomes in patients with peripheral artery disease: A systematic review and meta-analysis. Journal Of Affective Disorders 2022, 320: 169-177. PMID: 36179780, DOI: 10.1016/j.jad.2022.09.098.Peer-Reviewed Original ResearchConceptsMajor adverse limb eventsPeripheral artery diseaseAssociation of depressionCause mortalityArtery diseaseDepressive symptomsSystematic reviewAdverse limb eventsAdverse prognostic outcomeCoronary artery diseaseRisk of biasImportant comorbidityPoor outcomeAdverse outcomesPrognostic outcomesPooled resultsRisk factorsObservational studyTreatment statusLimb eventsDepression severityPatientsLarger sample sizeMortalityRisk estimates
2021
Antiplatelet Monotherapy Is Associated with an Increased Risk of Bleeding After Endoscopic Sphincterotomy
Zakko A, Zakko L, Grimshaw AA, Laine L. Antiplatelet Monotherapy Is Associated with an Increased Risk of Bleeding After Endoscopic Sphincterotomy. Digestive Diseases And Sciences 2021, 67: 4161-4169. PMID: 34796411, DOI: 10.1007/s10620-021-07302-w.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyPost-sphincterotomy bleedingAntiplatelet monotherapyInclusion criteriaRisk of bleedingROBINS-I toolNewcastle-Ottawa ScaleHigh-quality studiesRandom-effects modelBackgroundClinical guidelinesAntithrombotic therapyAdult patientsCohort studyEndoscopic sphincterotomyPrimary outcomeAntiplatelet agentsOvid EmbaseRetrograde cholangiopancreatographyCochrane LibraryOvid MEDLINEMonotherapyMethodological qualityBleedingUnique citationsPatientsEvaluation of diagnostic yield of EUS among patients with asymptomatic common bile duct dilation: systematic review and meta-analysis
Chhoda A, Dawod S, Grimshaw A, Gunderson C, Mahadev S. Evaluation of diagnostic yield of EUS among patients with asymptomatic common bile duct dilation: systematic review and meta-analysis. Gastrointestinal Endoscopy 2021, 94: 890-901.e8. PMID: 34245751, DOI: 10.1016/j.gie.2021.07.002.Peer-Reviewed Original ResearchConceptsCommon bile duct dilationBile duct dilationAsymptomatic patientsBiliary dilationDiagnostic yieldCBD dilationDuct dilationEUS evaluationSystematic reviewHealth resource utilizationInverse variance methodRandom-effects modelCost-effectiveness analysisRadiologic evidenceBenign etiologyMalignant etiologyFrequent indicationOvid EmbaseAsymptomatic individualsCochrane LibraryMalignant pathologyOvid MEDLINEFurther interventionPatientsGoogle Scholar
2020
Prediction of outcomes after acute kidney injury in hospitalised patients: protocol for a systematic review
Arora T, Martin M, Grimshaw A, Mansour S, Wilson FP. Prediction of outcomes after acute kidney injury in hospitalised patients: protocol for a systematic review. BMJ Open 2020, 10: e042035. PMID: 33371041, PMCID: PMC7757434, DOI: 10.1136/bmjopen-2020-042035.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPrediction of outcomeSystematic reviewKidney injuryOutcomes of AKIResolution of AKIProgression of AKILong-term outcomesBias assessment toolRisk of biasMultivariable predictive modelMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsFull-text reviewPrediction model RiskAKI careCohort studyNegative long-term outcomesThird reviewerReporting ItemsAbstract screeningComprehensive searchPatientsCommon diseaseData extractionEvaluation of Daratumumab for the Treatment of Multiple Myeloma in Patients With High-risk Cytogenetic Factors
Giri S, Grimshaw A, Bal S, Godby K, Kharel P, Djulbegovic B, Dimopoulos MA, Facon T, Usmani SZ, Mateos MV, Costa LJ. Evaluation of Daratumumab for the Treatment of Multiple Myeloma in Patients With High-risk Cytogenetic Factors. JAMA Oncology 2020, 6: 1759-1765. PMID: 32970151, PMCID: PMC7516804, DOI: 10.1001/jamaoncol.2020.4338.Peer-Reviewed Original ResearchConceptsProgression-free survivalHigh-risk MMBackbone regimensRefractory MMHazard ratioMultiple myelomaClinical trialsSystematic reviewDerSimonian-Laird random-effects modelPhase 3 trialImproved response ratesPreferred Reporting ItemsRandom-effects modelCochrane riskSame regimenCytogenetic riskCochrane LibraryMeeting libraryI2 statisticImproved outcomesMAIN OUTCOMEThird investigatorCochran's QPatientsReporting ItemsEfficacy and safety of frontline regimens for older transplant-ineligible patients with multiple myeloma: A systematic review and meta-analysis
Giri S, Aryal MR, Yu H, Grimshaw A, Pathak R, Huntington SP, Dhakal B. Efficacy and safety of frontline regimens for older transplant-ineligible patients with multiple myeloma: A systematic review and meta-analysis. Journal Of Geriatric Oncology 2020, 11: 1285-1292. PMID: 32513568, PMCID: PMC8721742, DOI: 10.1016/j.jgo.2020.05.013.Peer-Reviewed Original ResearchConceptsTransplant-ineligible patientsMultiple myelomaTreatment optionsPhase II/IIICumulative ranking (SUCRA) probabilitiesFirst-line treatmentHematopoietic cell transplantationTerms of efficacyRandom-effects modelEfficacious regimensFrailty biomarkersFrontline regimensThalidomide maintenanceEffective regimensGeriatric assessmentLine treatmentTreatment regimensCell transplantationMeeting libraryIndividual patientsToxicity profileRegimensPatientsSystematic reviewRanking probabilityPrevalence of harmful diagnostic errors in hospitalised adults: a systematic review and meta-analysis
Gunderson CG, Bilan VP, Holleck JL, Nickerson P, Cherry BM, Chui P, Bastian LA, Grimshaw AA, Rodwin BA. Prevalence of harmful diagnostic errors in hospitalised adults: a systematic review and meta-analysis. BMJ Quality & Safety 2020, 29: 1008-1018. PMID: 32269070, DOI: 10.1136/bmjqs-2019-010822.Peer-Reviewed Original ResearchConceptsAdverse eventsDiagnostic errorsPhysician reviewSystematic reviewInpatient adverse eventsRisk of biasPatient safety hazardsSystem-related factorsSystematic literature searchWeb of SciencePulmonary embolismAdult patientsCase seriesCommon diagnosisPooled rateAdult admissionsCochrane LibraryDatabase inceptionDiagnostic error rateStudy characteristicsLiterature searchPatientsCommon diseaseDiagnosisCommon beingRate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis
Rodwin BA, Bilan VP, Merchant NB, Steffens CG, Grimshaw AA, Bastian LA, Gunderson CG. Rate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis. Journal Of General Internal Medicine 2020, 35: 2099-2106. PMID: 31965525, PMCID: PMC7351940, DOI: 10.1007/s11606-019-05592-5.Peer-Reviewed Original ResearchConceptsInpatient deathPreventable mortalityPreventable deathsMortality rateHospital mortality rateLife expectancyRandom-effects modelSystematic literature searchNumber of deathsWeb of ScienceHospital deathAdult patientsHospitalized patientsResultsSixteen studiesCase seriesPooled rateCochrane LibraryInclusion criteriaPatientsMeta-AnalysisSystematic reviewLiterature searchData extractionMortalityDeath