2008
The Relevance of Research on Red Cell Membranes to the Understanding of Complex Human Disease: A Personal Perspective
Marchesi VT. The Relevance of Research on Red Cell Membranes to the Understanding of Complex Human Disease: A Personal Perspective. Annual Review Of Pathology Mechanisms Of Disease 2008, 3: 1-9. PMID: 18039128, DOI: 10.1146/annurev.pathmechdis.3.121806.154321.Peer-Reviewed Original ResearchConceptsCell membrane proteinsMembrane proteinsHuman cell membrane proteinsHuman diseasesRed blood cell membrane proteinsComplex human diseasesMolecular biological studiesRed cell membraneRecombinant DNAMolecular analysisCell membraneHuman erythrocyte membranesService of researchBiological studiesProteinErythrocyte membranesMembrane
2005
An alternative interpretation of the amyloid Aβ hypothesis with regard to the pathogenesis of Alzheimer's disease
Marchesi VT. An alternative interpretation of the amyloid Aβ hypothesis with regard to the pathogenesis of Alzheimer's disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 9093-9098. PMID: 15967987, PMCID: PMC1166615, DOI: 10.1073/pnas.0503181102.Peer-Reviewed Original ResearchAmino Acid MotifsAmino Acid SequenceAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAmyloid Precursor Protein SecretasesCell MembraneCentral Nervous SystemDimerizationEndopeptidasesHumansLipid BilayersMembrane GlycoproteinsMembrane ProteinsModels, BiologicalMolecular Sequence DataNeuronsPeptide HydrolasesPeptidesPresenilin-1Protein BindingSequence Homology, Amino AcidSodium Dodecyl SulfateTemperature
1998
www.fasebj.org
Marchesi V. www.fasebj.org. The FASEB Journal 1998, 12: 1253-1253. PMID: 9761769, DOI: 10.1096/fasebj.12.13.1253.Peer-Reviewed Original ResearchFrom Molecular Analysis to Medical Practice: Recent Studies Reveal New Therapeutic Targets for an Old Medicine
Marchesi V. From Molecular Analysis to Medical Practice: Recent Studies Reveal New Therapeutic Targets for an Old Medicine. The FASEB Journal 1998, 12: 1061-1061. PMID: 9737709, DOI: 10.1096/fasebj.12.12.1061.Peer-Reviewed Original ResearchHard Days … on the Endless Frontier? … or in the Trenches?
Marchesi V. Hard Days … on the Endless Frontier? … or in the Trenches? The FASEB Journal 1998, 12: 253-253. PMID: 9506464, DOI: 10.1096/fasebj.12.3.253.Peer-Reviewed Original Research“According to the definition of intellectual property,” Mario Biagioli notes, “a scientist is literally a non-author.”
Marchesi V. “According to the definition of intellectual property,” Mario Biagioli notes, “a scientist is literally a non-author.”. The FASEB Journal 1998, 12: 1-1. DOI: 10.1096/fasebj.12.1.1.Peer-Reviewed Original Research“According to the definition of intellectual property,” Mario Biagioli notes, “a scientist is literally a non‐author.”
Marchesi V. “According to the definition of intellectual property,” Mario Biagioli notes, “a scientist is literally a non‐author.”. The FASEB Journal 1998, 12: 1-1. DOI: 10.1096/fsb2fasebj.12.1.1.Peer-Reviewed Original Research
1996
The Life Sciences Forum–A Call for Contributions
Marchesi V. The Life Sciences Forum–A Call for Contributions. The FASEB Journal 1996, 10: 1111-1111. PMID: 8751712, DOI: 10.1096/fasebj.10.10.8751712.Peer-Reviewed Original Research
1995
Yale’s Boyer Center for Molecular Medicine
Marchesi V. Yale’s Boyer Center for Molecular Medicine. Molecular Medicine 1995, 1: 477-478. PMID: 8529113, PMCID: PMC2229965, DOI: 10.1007/bf03401584.Peer-Reviewed Original Research
1993
In vitro assembly of multiprotein complexes containing alpha, beta, and gamma tubulin, heat shock protein HSP70, and elongation factor 1 alpha.
Marchesi V, Ngo N. In vitro assembly of multiprotein complexes containing alpha, beta, and gamma tubulin, heat shock protein HSP70, and elongation factor 1 alpha. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 3028-3032. PMID: 8464918, PMCID: PMC46230, DOI: 10.1073/pnas.90.7.3028.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCentrifugation, Density GradientCHO CellsCricetinaeElectrophoresis, Polyacrylamide GelHeat-Shock ProteinsHeLa CellsHumansImmunoblottingMacromolecular SubstancesMitosisModels, StructuralMolecular WeightNocodazolePeptide Elongation Factor 1Peptide Elongation FactorsRibonucleoproteinsTubulinConceptsElongation factor 1 alphaHeat shock protein Hsp70Multiprotein complexesShock protein Hsp70Factor 1 alphaGamma-tubulinProtein Hsp70Regulation of mitosisPresence of ATPDistinct complexesMitotic centrosomesActin isoformsSucrose gradient ultracentrifugationVitro assemblyTubulin isoformsLow abundanceCHO cellsHSP70Degrees C incubationProteinCognate formIsoformsSmall precursorsHigh-speed centrifugationComplexes
1987
Interaction of platelet protein 4.1 with the cytoskeleton of activated platelets
Horne W, Golish C, Marchesi V. Interaction of platelet protein 4.1 with the cytoskeleton of activated platelets. Journal Of Molecular And Cellular Cardiology 1987, 19: s15. DOI: 10.1016/s0022-2828(87)80668-5.Peer-Reviewed Original Research
1985
Stabilizing Infrastructure of Cell Membranes
Marchesi V. Stabilizing Infrastructure of Cell Membranes. Annual Review Of Cell And Developmental Biology 1985, 1: 531-561. PMID: 3916322, DOI: 10.1146/annurev.cb.01.110185.002531.Peer-Reviewed Original ResearchVimentin Binds to the Human RBC Membrane and Associates with Ankyrin
GEORGATOS S, WEAVER D, MARCHESI V. Vimentin Binds to the Human RBC Membrane and Associates with Ankyrin. Annals Of The New York Academy Of Sciences 1985, 455: 691-693. DOI: 10.1111/j.1749-6632.1985.tb50446.x.Peer-Reviewed Original ResearchSite specificity in vimentin-membrane interactions: intermediate filament subunits associate with the plasma membrane via their head domains.
Georgatos S, Weaver D, Marchesi V. Site specificity in vimentin-membrane interactions: intermediate filament subunits associate with the plasma membrane via their head domains. Journal Of Cell Biology 1985, 100: 1962-1967. PMID: 3158665, PMCID: PMC2113597, DOI: 10.1083/jcb.100.6.1962.Peer-Reviewed Original ResearchThe binding of vimentin to human erythrocyte membranes: a model system for the study of intermediate filament-membrane interactions.
Georgatos S, Marchesi V. The binding of vimentin to human erythrocyte membranes: a model system for the study of intermediate filament-membrane interactions. Journal Of Cell Biology 1985, 100: 1955-1961. PMID: 3158664, PMCID: PMC2113610, DOI: 10.1083/jcb.100.6.1955.Peer-Reviewed Original ResearchConceptsBinding of vimentinProtein 4.1Membrane vesiclesAnti-ankyrin antibodiesErythrocyte membrane skeletonHuman erythrocyte membrane vesiclesIntermediate filament proteinsErythrocyte membrane vesiclesMajor attachment siteMembrane skeletonPlasma membraneBinding functionsAnkyrinFilament proteinsCytoplasmic fragmentsBand 4.5Glycophorin ASpectrinVesiclesAttachment sitesHuman erythrocyte membranesBand 3
1984
Isolation of spectrin subunits and reassociation in vitro. Analysis by fluorescence polarization.
Yoshino H, Marchesi V. Isolation of spectrin subunits and reassociation in vitro. Analysis by fluorescence polarization. Journal Of Biological Chemistry 1984, 259: 4496-4500. PMID: 6707015, DOI: 10.1016/s0021-9258(17)43074-2.Peer-Reviewed Original ResearchConceptsFluorescence anisotropy changesFluorescence polarizationEventual dissociationGood yieldsDEAE-cellulose column chromatographyOligomeric speciesMonomer stateColumn chromatographyNeutral salt solutionsElectron microscopyAcrylamide gel electrophoresisSalt solutionLow-angle shadowingM ureaTryptophan residuesBeta subunitPure alphaSpectrinSubdomain structureSpectrin moleculesSubunitsLow concentrationsErythrocyte spectrinSpectrin subunitsGel electrophoresisStructure and function of the erythrocyte membrane skeleton.
Marchesi V. Structure and function of the erythrocyte membrane skeleton. Progress In Clinical And Biological Research 1984, 159: 1-12. PMID: 6236465.Peer-Reviewed Original Research
1983
The red cell membrane skeleton: recent progress.
Marchesi V. The red cell membrane skeleton: recent progress. Blood 1983, 61: 1-11. PMID: 6293625, DOI: 10.1182/blood.v61.1.1.bloodjournal6111.Peer-Reviewed Original Research
1982
The membrane skeleton as a potential target for toxic agents.
Marchesi V. The membrane skeleton as a potential target for toxic agents. Mead Johnson Symposium On Perinatal And Developmental Medicine 1982, 13-6. PMID: 6765455.Peer-Reviewed Original Research
1981
Immunobiology of the Erythrocyte . S. Gerald Sandler , Jacob Nusbacher , Moses S. Schanfield
Marchesi V. Immunobiology of the Erythrocyte . S. Gerald Sandler , Jacob Nusbacher , Moses S. Schanfield. The Quarterly Review Of Biology 1981, 56: 520-520. DOI: 10.1086/412562.Peer-Reviewed Original Research