2008
Alpha and Gamma Isoforms of the Type I Phosphatidylinositol 4‐phosphate 5‐kinase Regulate Distinct Stages of the Ca2+ Response in Mast Cells
Vasudevan L, Jeromin A, Volpicelli‐Daley L, De Camilli P, Baird B, Holowka D. Alpha and Gamma Isoforms of the Type I Phosphatidylinositol 4‐phosphate 5‐kinase Regulate Distinct Stages of the Ca2+ Response in Mast Cells. The FASEB Journal 2008, 22: 804.1-804.1. DOI: 10.1096/fasebj.22.1_supplement.804.1.Peer-Reviewed Original ResearchMast cellsER storesMast cell responsesRBL-2H3 mast cellsType IInflammatory mediatorsKO miceBone marrowStore-operated Ca 2IgE receptorCell responsesAntigen crosslinkingExocytotic releaseIP 3 receptorsCa 2Hydrolysis of phosphatidylinositolAntigenReceptorsEndoplasmic reticulumCellular localizationGamma isoformsInfluxCells
2001
Glutamate regulates actin-based motility in axonal filopodia
Chang S, De Camilli P. Glutamate regulates actin-based motility in axonal filopodia. Nature Neuroscience 2001, 4: 787-793. PMID: 11477424, DOI: 10.1038/90489.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBridged Bicyclo Compounds, HeterocyclicCalciumCalcium ChannelsCell DifferentiationCell MovementCells, CulturedCentral Nervous SystemGlutamic AcidGreen Fluorescent ProteinsGrowth ConesHippocampusImmunohistochemistryLuminescent ProteinsNeuronal PlasticityPseudopodiaRatsReceptors, AMPAReceptors, N-Methyl-D-AspartateTau ProteinsThiazolesThiazolidinesConceptsAdult nervous systemGlutamate receptorsNervous systemAxonal filopodiaAMPA/kainate glutamate receptorsKainate glutamate receptorsEffects of glutamateIonotropic glutamate receptorsCNQX treatmentSynaptic vesicle clustersAxonal arborsAxonal branchesDendritic spinesExtracellular Ca2Neurotransmitter glutamateSynaptic formationSynaptic plasticityInhibitory effectGlutamateReceptorsVesicle clustersNMDASynaptogenesisSpine
1989
Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor
Mignery G, Südhof T, Takei K, De Camilli P. Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor. Nature 1989, 342: 192-195. PMID: 2554146, DOI: 10.1038/342192a0.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsCalcium ChannelsCerebellumCloning, MolecularFluorescent Antibody TechniqueImmunohistochemistryInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsIntracellular MembranesMiceMolecular Sequence DataPurkinje CellsReceptors, Cell SurfaceReceptors, CholinergicReceptors, Cytoplasmic and NuclearRyanodineRyanodine Receptor Calcium Release ChannelConceptsEndoplasmic reticulumCalcium channel proteinsIntracellular second messengerRelative molecular massIntracellular membranesSecond messengerIntracellular compartmentsMolecular massEfficacy of neurotransmissionPutative receptorDirect roleProteinCalcium releaseGrowth factorReticulumDendritic spinesTrisphosphateIntracellular storesPresynaptic terminalsInositolIntracellular calcium storesReceptorsCalcium storesRNA6Immunocytochemistry
1979
Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas
DE CAMILLI P, MACCONI D, SPADA A. Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas. Nature 1979, 278: 252-254. PMID: 423973, DOI: 10.1038/278252a0.Peer-Reviewed Original ResearchConceptsDA receptorsPRL secretionProlactin-secreting pituitary adenomasAdenylate cyclaseBasal adenylate cyclaseSame pharmacological propertiesClasses of receptorsDopamine inhibitsDopaminergic agonistsProlactin secretionPituitary adenomasNormal anteriorPRL adenomasPharmacological propertiesReceptorsSecretionCyclic AMPAdenomasCyclaseAgonistsAnteriorPRL