2020
Dynamin Function in Exocytosis and Endocytosis Coupling of Dense-Core Vesicles in Pancreatic Beta Cells
Fan F, Wendlick J, Tamarina N, Wu Y, Ferguson S, Philipson L, De Camilli P, Lou X. Dynamin Function in Exocytosis and Endocytosis Coupling of Dense-Core Vesicles in Pancreatic Beta Cells. Biophysical Journal 2020, 118: 488a. DOI: 10.1016/j.bpj.2019.11.2700.Peer-Reviewed Original Research
1994
A role for synaptic vesicles in non‐neuronal cells: clues from pancreatic β cells and from chromaffin cells
Thomas‐Reetz A, De Camilli P. A role for synaptic vesicles in non‐neuronal cells: clues from pancreatic β cells and from chromaffin cells. The FASEB Journal 1994, 8: 209-216. PMID: 7907072, DOI: 10.1096/fasebj.8.2.7907072.Peer-Reviewed Original ResearchConceptsSynaptic-like microvesiclesSynaptic vesiclesAbundant synaptic vesicle proteinsVesicular carriersPancreatic beta cellsSynaptic vesicle proteinsVesicular trafficNon-neuronal cellsRecycling compartmentMembrane proteinsRecycling pathwayVesicle proteinsPancreatic β-cellsPeptide-secreting endocrine cellsMolecular mechanismsSpecialized subcompartmentBeta cellsPC12 cellsMembrane compositionVesiclesCell linesΒ-cellsOrganellesNeurotransmitter releaseNeurotransmitter-like substances
1991
Autoimmunity to glutamic acid decarboxylase (GAD) in stiffman syndrome and insulin-dependent diabetes mellitus
Solimena M, De Camilli P. Autoimmunity to glutamic acid decarboxylase (GAD) in stiffman syndrome and insulin-dependent diabetes mellitus. Trends In Neurosciences 1991, 14: 452-457. PMID: 1722364, DOI: 10.1016/0166-2236(91)90044-u.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusStiff-man syndromeGlutamic acid decarboxylaseDiabetes mellitusAcid decarboxylaseEnzyme glutamic acid decarboxylaseMain inhibitory neurotransmitterStiffman syndromeAutoimmune targetGABAergic neurotransmissionAutoimmune responseAutoimmune diseasesInhibitory neurotransmitterBeta cellsMellitusBody musculatureSyndromeGABAPutative signal moleculesPossible significanceAutoantibodiesAutoimmunityDecarboxylaseNeurotransmissionCNS
1990
Autoantibodies to GABA-ergic Neurons and Pancreatic Beta Cells in Stiff-Man Syndrome
Solimena M, Folli F, Aparisi R, Pozza G, De Camilli P. Autoantibodies to GABA-ergic Neurons and Pancreatic Beta Cells in Stiff-Man Syndrome. New England Journal Of Medicine 1990, 322: 1555-1560. PMID: 2135382, DOI: 10.1056/nejm199005313222202.Peer-Reviewed Original ResearchConceptsStiff-man syndromeInsulin-dependent diabetes mellitusGABA-ergic neuronsGlutamic acid decarboxylaseGamma-aminobutyric acidDiabetes mellitusPancreatic beta cellsAutoimmune diseasesBeta cellsOrgan-specific autoimmune diseasesNeurotransmitter gamma-aminobutyric acidPresence of autoantibodiesGroup of patientsCentral nervous systemPrimary autoantigenUnknown pathogenesisRare disorderAutoantibodiesNervous systemSyndromeUseful markerMellitusAcid decarboxylaseStriking associationPatients