1998
Induction of transporter associated with antigen processing by interferon γ confers endothelial cell cytoprotection against natural killer-mediated lysis
Ayalon O, Hughes E, Cresswell P, Lee J, O’Donnell L, Pardi R, Bender J. Induction of transporter associated with antigen processing by interferon γ confers endothelial cell cytoprotection against natural killer-mediated lysis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 2435-2440. PMID: 9482903, PMCID: PMC19366, DOI: 10.1073/pnas.95.5.2435.Peer-Reviewed Original ResearchConceptsMHC IInduction of transportersEndothelial cellsNK-resistant cell linesNatural killer-mediated lysisMajor histocompatibility complex INK inhibitory receptorsNK effector cellsPretreatment of ECB-lymphoblastoid cell linesEC sensitivityDermal microvascular endothelial cellsMicrovascular endothelial cellsCell linesHuman umbilical vein endothelial cellsExpression/functionUmbilical vein endothelial cellsAdenoviral-mediated transductionVascular vulnerabilityVein endothelial cellsNK assaysEffector cellsEndothelial activationInhibitory receptorsDeficient targets
1996
Class I-like CD1A-C Do Not Protect Target Cells from NK-Mediated Cytolysis
Storkus W, Wei M, Cresswell P, Dawson J. Class I-like CD1A-C Do Not Protect Target Cells from NK-Mediated Cytolysis. Cellular Immunology 1996, 167: 154-156. PMID: 8548840, DOI: 10.1006/cimm.1996.0020.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, CD1Cell LineCytotoxicity, ImmunologicHistocompatibility Antigens Class IHumansKiller Cells, NaturalTransfectionConceptsClass INatural killer cell-mediated cytolysisTarget cellsCell-mediated cytolysisTarget cell susceptibilityNonclassical MHC class IHLA class ITarget cell sensitivityMHC class INatural killingNK cellsCD1c moleculesElevated expressionCell susceptibilityCell sensitivityCD1aCytolysisNKClonal transfectantsRelevant levelsCellsCell surfaceLysisPrevious studiesCD1b