1996
HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules
Denzin L, Hammond C, Cresswell P. HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules. Journal Of Experimental Medicine 1996, 184: 2153-2166. PMID: 8976171, PMCID: PMC2196380, DOI: 10.1084/jem.184.6.2153.Peer-Reviewed Original ResearchConceptsClass II moleculesHLA-DR moleculesHLA-DMDR moleculesMajor histocompatibility complex classAntigenic peptidesEmpty class II moleculesCLIP dissociationHistocompatibility complex classMHC class II compartmentsHLA-DM moleculesClass II compartmentsII-CLIP complexesClass II dimersAlpha beta dimersAntigen processingBeta dimersDR complexesCell linesInvariant chain fragmentComplex classAssociationLow levels
1994
In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides
Avva R, Cresswell P. In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides. Immunity 1994, 1: 763-774. PMID: 7895165, DOI: 10.1016/s1074-7613(94)80018-9.Peer-Reviewed Original ResearchConceptsHLA-DM expressionDR alpha beta dimersHLA-DR moleculesCLIP dissociationClass II moleculesHLA-DR complexInvariant chain peptideII-peptide complexesPrimary aliphatic aminesResidual fragmentsChain-derived peptideClass IIHLA-DMAliphatic aminesCarboxylic acidsSuch complexesUnbranched hydrocarbonsAlpha beta dimersChain peptideInvariant chain-derived peptidesComplexesVivoCLIP complexBeta dimersDissociation