2001
Myosin-VIIb, a Novel Unconventional Myosin, Is a Constituent of Microvilli in Transporting Epithelia
Chen Z, Hasson T, Zhang D, Schwender B, Derfler B, Mooseker M, Corey D. Myosin-VIIb, a Novel Unconventional Myosin, Is a Constituent of Microvilli in Transporting Epithelia. Genomics 2001, 72: 285-296. PMID: 11401444, DOI: 10.1006/geno.2000.6456.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsBase SequenceBiological TransportBlotting, NorthernBlotting, WesternChromosome MappingCloning, MolecularDNA, ComplementaryEpitheliumExonsFemaleGenesImmunohistochemistryIntestinesIntronsKidneyMiceMice, Inbred BALB CMicrovilliMolecular Sequence DataMyosinsPhylogenyProtein IsoformsRNA, MessengerSequence AlignmentSequence Analysis, DNASequence Homology, Amino AcidTissue Distribution
1999
Cloning and characterization of mouse brush border myosin‐I in adult and embryonic intestine
Skowron J, Mooseker M. Cloning and characterization of mouse brush border myosin‐I in adult and embryonic intestine. Journal Of Experimental Zoology 1999, 283: 242-257. PMID: 9933937, DOI: 10.1002/(sici)1097-010x(19990215)283:3<242::aid-jez3>3.0.co;2-f.Peer-Reviewed Original ResearchConceptsBrush border myosinMicrovillar actin bundlesEmbryonic intestineSubcellular localization profileBasolateral membrane domainsGenomic clonesCalmodulin light chainsVertebrate speciesMembrane domainsActin corePlasma membraneKnockout strategiesActin bundlesImmunolocalization studiesIntestinal epithelial cellsGolgi apparatusNorthern analysisPrimary structureNorthern blotSitu localizationLocalization profilesRNA expressionEmbryosDirect targetingEmbryogenesis
1994
Multiple unconventional myosin domains of the intestinal brush border cytoskeleton
Heintzelman M, Hasson T, Mooseker M. Multiple unconventional myosin domains of the intestinal brush border cytoskeleton. Journal Of Cell Science 1994, 107: 3535-3543. PMID: 7706404, DOI: 10.1242/jcs.107.12.3535.Peer-Reviewed Original Research
1992
Localization of capping protein in chicken epithelial cells by immunofluorescence and biochemical fractionation.
Schafer D, Mooseker M, Cooper J. Localization of capping protein in chicken epithelial cells by immunofluorescence and biochemical fractionation. Journal Of Cell Biology 1992, 118: 335-346. PMID: 1629237, PMCID: PMC2290044, DOI: 10.1083/jcb.118.2.335.Peer-Reviewed Original ResearchMeSH KeywordsActin Depolymerizing FactorsActinsAnimalsAntibodiesCells, CulturedChick EmbryoChickensCochleaDestrinElectrophoresis, Polyacrylamide GelEpithelial CellsEpitheliumFluorescent Antibody TechniqueIntestinesKidneyMacromolecular SubstancesMicrofilament ProteinsMicrovilliMusclesPigment Epithelium of EyeSubcellular FractionsConceptsIntestinal epithelial cellsNuclei of cellsBiochemical fractionationJunctional complexesActin filamentsCell-cell junctional complexesSingle intestinal epithelial cellsBarbed endsEpithelial cellsSensory epitheliumCell-cell contactIntact intestinal epithelial cellsAffinity-purified polyclonal antibodiesProtein bindsCapping proteinIntestinal epitheliumZonula adherensCell junctionsChick embryo kidney cellsPattern coincidentEmbryo kidney cellsProteinConfocal microscopyKidney cellsIsolated intestinal epithelial cellsThe molecular architecture of an insect midgut brush border cytoskeleton.
Bonfanti P, Colombo A, Heintzelman M, Mooseker M, Camatini M. The molecular architecture of an insect midgut brush border cytoskeleton. European Journal Of Cell Biology 1992, 57: 298-307. PMID: 1511705.Peer-Reviewed Original ResearchConceptsTwo-dimensional gel analysisMolecular architectureMultiple isoelectric variantsBrush border cytoskeletonLepidopteran larvaeBB myosin IVertebrate intestineBrush borderMyosin IOrganelle exclusionHeavy meromyosin decorationCytoskeletal apparatusMyosin IINonmuscle cellsActin filamentsCytoskeletonIsoelectric variantsGel analysisInstar larvaeMajor isoformsStructural organizationRhodamine phalloidinCore proteinIntestinal brush borderMidgut6 Assembly of the Intestinal Brush Border Cytoskeleton
Heintzelman M, Mooseker M. 6 Assembly of the Intestinal Brush Border Cytoskeleton. Current Topics In Developmental Biology 1992, 26: 93-122. PMID: 1563281, DOI: 10.1016/s0070-2153(08)60442-1.Peer-Reviewed Original Research
1990
Structural and compositional analysis of early stages in microvillus assembly in the enterocyte of the chick embryo
Heintzelman M, Mooseker M. Structural and compositional analysis of early stages in microvillus assembly in the enterocyte of the chick embryo. Differentiation 1990, 43: 175-182. PMID: 2387484, DOI: 10.1111/j.1432-0436.1990.tb00444.x.Peer-Reviewed Original Research
1989
Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family.
Garcia A, Coudrier E, Carboni J, Anderson J, Vandekerkhove J, Mooseker M, Louvard D, Arpin M. Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family. Journal Of Cell Biology 1989, 109: 2895-2903. PMID: 2687288, PMCID: PMC2115973, DOI: 10.1083/jcb.109.6.2895.Peer-Reviewed Original ResearchCharacterization of intestinal microvillar membrane disks: detergent-resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin).
Mooseker M, Conzelman K, Coleman T, Heuser J, Sheetz M. Characterization of intestinal microvillar membrane disks: detergent-resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin). Journal Of Cell Biology 1989, 109: 1153-1161. PMID: 2527857, PMCID: PMC2115773, DOI: 10.1083/jcb.109.3.1153.Peer-Reviewed Original ResearchThe 110-kD protein-calmodulin complex of the intestinal microvillus (brush border myosin I) is a mechanoenzyme.
Mooseker M, Coleman T. The 110-kD protein-calmodulin complex of the intestinal microvillus (brush border myosin I) is a mechanoenzyme. Journal Of Cell Biology 1989, 108: 2395-2400. PMID: 2525564, PMCID: PMC2115599, DOI: 10.1083/jcb.108.6.2395.Peer-Reviewed Original Research
1987
Characterization of intestinal brush border cytoskeletal proteins of normal and neoplastic human epithelial cells. A comparison with the avian brush border.
Carboni J, Howe C, West A, Barwick K, Mooseker M, Morrow J. Characterization of intestinal brush border cytoskeletal proteins of normal and neoplastic human epithelial cells. A comparison with the avian brush border. American Journal Of Pathology 1987, 129: 589-600. PMID: 3425692, PMCID: PMC1899811.Peer-Reviewed Original ResearchConceptsMicrovillar actin bundlesActin binding proteinsHuman brush borderIntestinal epithelial cell brush bordersEpithelial cell brush bordersBrush borderMicrovillar proteinsHuman epithelial cellsCytoskeletal matrixCytoskeletal proteinsMultiple proteinsActin bundlesImmunolocalization studiesSpectrin isoformsMammalian sourcesMajor proteinsDifferentiation stateBinding proteinProtein myosinProteinTerminal webCell brush borderCytoskeletonNeoplastic stateMature enterocytesThe 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase.
Conzelman K, Mooseker M. The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase. Journal Of Cell Biology 1987, 105: 313-324. PMID: 2956266, PMCID: PMC2114910, DOI: 10.1083/jcb.105.1.313.Peer-Reviewed Original Research
1984
Brush border cytoskeleton and integration of cellular functions.
Mooseker M, Bonder E, Conzelman K, Fishkind D, Howe C, Keller T. Brush border cytoskeleton and integration of cellular functions. Journal Of Cell Biology 1984, 99: 104s-112s. PMID: 6378918, PMCID: PMC2275581, DOI: 10.1083/jcb.99.1.104s.Peer-Reviewed Original ResearchThe cytoskeletal apparatus of the intestinal brush border.
Mooseker M, Bonder E, Conzelman K, Fishkind D, Howe C, Keller T. The cytoskeletal apparatus of the intestinal brush border. Kroc Foundation Series 1984, 17: 287-307. PMID: 6392486.Peer-Reviewed Original ResearchCalcium-dependent regulation of cytoskeletal structure and contractility in the intestinal brush border.
Mooseker M. Calcium-dependent regulation of cytoskeletal structure and contractility in the intestinal brush border. Progress In Clinical And Biological Research 1984, 168: 179-86. PMID: 6542665.Peer-Reviewed Original Research
1982
Regulation of contractility, cytoskeletal structure, and filament assembly in the brush border of intestinal epithelial cells.
Mooseker M, Bonder E, Grimwade B, Howe C, Keller T, Wasserman R, Wharton K. Regulation of contractility, cytoskeletal structure, and filament assembly in the brush border of intestinal epithelial cells. Cold Spring Harbor Symposia On Quantitative Biology 1982, 46 Pt 2: 855-70. PMID: 6955109, DOI: 10.1101/sqb.1982.046.01.080.Peer-Reviewed Original Research
1971
Actin in the Brush-Border of Epithelial Cells of the Chicken Intestine
Tilney L, Mooseker M. Actin in the Brush-Border of Epithelial Cells of the Chicken Intestine. Proceedings Of The National Academy Of Sciences Of The United States Of America 1971, 68: 2611-2615. PMID: 4944636, PMCID: PMC389479, DOI: 10.1073/pnas.68.10.2611.Peer-Reviewed Original Research