2010
The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells
Huranová M, Ivani I, Benda A, Poser I, Brody Y, Hof M, Shav-Tal Y, Neugebauer KM, Staněk D. The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells. Journal Of Cell Biology 2010, 191: 75-86. PMID: 20921136, PMCID: PMC2953428, DOI: 10.1083/jcb.201004030.Peer-Reviewed Original ResearchConceptsSmall nuclear RNP particlesPrecursor messenger RNA splicingMessenger RNA splicingBinding of U1Live-cell imagingRate of splicingNuclear RNP particlesLarge ribonucleoproteinSnRNP componentsRNA splicingSpliceosome assemblyAdditional proteinsRNP particlesHuman cellsSplicingLiving cellsCell nucleiDifferential interactionsEndogenous levelsSpliceosomeMRNARibonucleoproteinCell imagingCore componentCells
1992
Adhesion of a chicken myeloblast cell line to fibrinogen and vitronectin through a beta 1-class integrin.
Neugebauer K, Venstrom K, Reichardt L. Adhesion of a chicken myeloblast cell line to fibrinogen and vitronectin through a beta 1-class integrin. Journal Of Cell Biology 1992, 116: 809-815. PMID: 1370500, PMCID: PMC2289312, DOI: 10.1083/jcb.116.3.809.Peer-Reviewed Original ResearchConceptsMyeloblast cell lineHD11 cellsCell adhesionCell linesExtracellular matrix ligandsExtracellular matrix proteinsAlpha v beta 3Function-perturbing antibodiesAdhesive interactionsExtracellular matrix constituentsSubunit associatesHD11 cell lineReceptor-mediated eventsMatrix ligandsBeta subunitIntegrin heterodimersMatrix proteinsFunction-blocking antibodiesAlpha vLipopolysaccharide treatmentPrimary macrophagesHeterodimersDistinct extracellular matrix (ECM) proteinsBeta 3Study of mechanisms