Thermodynamically driven assemblies and liquid–liquid phase separations in biology
Falahati H, Haji-Akbari A. Thermodynamically driven assemblies and liquid–liquid phase separations in biology. Soft Matter 2019, 15: 1135-1154. PMID: 30672955, DOI: 10.1039/c8sm02285b.Peer-Reviewed Original ResearchConceptsPhase separationBiological self-assembly processesSelf-assembly processLiquid-liquid phase separationUnderlying physical principlesDriven AssemblyIntermolecular interactionsPhysical originBiomolecular complexesMembraneless organellesMolecular simulationsPhysicsPhysical principlesStatistical physicsSeparationThermodynamic variablesExperimental verificationAssembly processSustenance of lifeThermodynamicsBiological implicationsAssemblyComputational techniquesSubcellular structuresEnergy