2021
Sex Differences in the Exocrine Pancreas and Associated Diseases
Wang M, Gorelick F, Bhargava A. Sex Differences in the Exocrine Pancreas and Associated Diseases. Cellular And Molecular Gastroenterology And Hepatology 2021, 12: 427-441. PMID: 33895424, PMCID: PMC8255941, DOI: 10.1016/j.jcmgh.2021.04.005.Peer-Reviewed Original ResearchConceptsPancreatic diseaseSex differencesExocrine pancreasLevels of estrogenAcute pancreatitis modelOverall health outcomesSex-specific mechanismsNormal exocrine pancreasG protein-coupled receptorsSex-specific changesMajor sex differencesObstructive etiologyPremenopausal womenProtein-coupled receptorsPancreatic surgeryAdrenal glandPancreatic histopathologyPancreatic secretionProtective effectLow prevalenceGranule numberDiagnostic criteriaPancreatitis modelPancreatic anatomyAssociated disease
1994
Effect of buprenorphine on pancreatic enzyme synthesis and secretion in normal rats and rats with acute edematous pancreatitis
Ogden JM, Modlin IM, Gorelick FS, Marks IN. Effect of buprenorphine on pancreatic enzyme synthesis and secretion in normal rats and rats with acute edematous pancreatitis. Digestive Diseases And Sciences 1994, 39: 2407-2415. PMID: 7525167, DOI: 10.1007/bf02087658.Peer-Reviewed Original ResearchConceptsAcute pancreatitisPancreatic enzyme secretionPancreatic enzyme synthesisAmylase secretionAmylase contentDevelopment of APEnzyme secretionSevere acute pancreatitisEffects of buprenorphineEffects of opiatesExperimental acute pancreatitisAcute edematous pancreatitisGroups of ratsSite of administrationNegative feedback inhibitionPancreatic edemaPancreatic stimulantsEdematous pancreatitisNormal ratsPancreatic massPancreatic secretionPancreatitisGroup IIControl groupGroup I