2018
Vesicle Tubulation with Self‐Assembling DNA Nanosprings
Grome MW, Zhang Z, Pincet F, Lin C. Vesicle Tubulation with Self‐Assembling DNA Nanosprings. Angewandte Chemie International Edition 2018, 57: 5330-5334. PMID: 29575478, PMCID: PMC5924453, DOI: 10.1002/anie.201800141.Peer-Reviewed Original ResearchMeSH KeywordsDNALipid BilayersMicroscopy, FluorescenceNanostructuresNanotechnologyNucleic Acid ConformationPolymerizationConceptsMembrane-deforming proteinsDNA origami designMembrane tubulationMembrane tubulesMembrane curvatureMembrane surface coverageVesicle tubulationDNA structureLipid bilayersTubulationNanospringsTube morphologyIntricate interplayArtificial nanomachinesVesicle deformationSpherical vesiclesNanotechnologyMajor goalProteinDNAVesiclesNanomachinesBioengineeringDetergentsMorphology
2011
Synthesis and Characterization of Self-Assembled DNA Nanostructures
Lin C, Ke Y, Chhabra R, Sharma J, Liu Y, Yan H. Synthesis and Characterization of Self-Assembled DNA Nanostructures. Methods In Molecular Biology 2011, 749: 1-11. PMID: 21674361, DOI: 10.1007/978-1-61779-142-0_1.ChaptersMeSH KeywordsDNA, Single-StrandedElectrophoresisMicroscopy, Atomic ForceNanostructuresNanotechnologyNucleic Acid ConformationOligonucleotidesConceptsDNA nanostructuresDNA nanotechnologySelf-assembled DNA nanostructuresSuch nanoscale objectsStructural DNA nanotechnologyCharacterization of SelfDNA-based nanodevicesExcellent yieldsNanoscale objectsNanostructuresArtificial nanostructuresMolecular speciesBuilding blocksNanotechnologyFast evolvementMain building blocksNanoarchitecturesLarge varietySynthesisMaterialsNanodevicesPreparationCharacterizationBuilding materialsYield
2009
A Replicable Tetrahedral Nanostructure Self-Assembled from a Single DNA Strand
Li Z, Wei B, Nangreave J, Lin C, Liu Y, Mi Y, Yan H. A Replicable Tetrahedral Nanostructure Self-Assembled from a Single DNA Strand. Journal Of The American Chemical Society 2009, 131: 13093-13098. PMID: 19737020, PMCID: PMC3083857, DOI: 10.1021/ja903768f.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceCloning, MolecularDNA ReplicationDNA, Single-StrandedModels, MolecularMolecular Sequence DataNanostructuresNucleic Acid ConformationConceptsAtomic force microscopy imagingForce microscopy imagingRolling-circle amplificationDNA nanostructuresSingle DNA strandsFerguson analysisMicroscopy imagingTetrahedraStandard molecular cloning techniquesDNA strandsSingle strandsRestriction enzyme digestionCloning techniquesMolecular cloning techniquesDesigner DNA Nanoarchitectures
Lin C, Liu Y, Yan H. Designer DNA Nanoarchitectures. Biochemistry 2009, 48: 1663-1674. PMID: 19199428, PMCID: PMC2765550, DOI: 10.1021/bi802324w.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStructural DNA nanotechnologyDNA nanotechnologyDNA nanoarchitecturesSelf-assembled architecturesWatson-Crick base pairing rulesProtein-protein interactionsBase pairing rulesDNA nanostructuresMulticomponent nanomachinesPrinciples of DNAArtificial nanostructuresNanometer precisionHelical DNA structureUnicellular diatomsFunctional groupsDNA structureNanotechnologyNanostructuresMolecular speciesNanoarchitecturesSuch eleganceExciting progressHigh yieldsBiological systemsDNA
2008
Mirror Image DNA Nanostructures for Chiral Supramolecular Assemblies
Lin C, Ke Y, Li Z, Wang JH, Liu Y, Yan H. Mirror Image DNA Nanostructures for Chiral Supramolecular Assemblies. Nano Letters 2008, 9: 433-436. PMID: 19063615, PMCID: PMC2669104, DOI: 10.1021/nl803328v.Peer-Reviewed Original ResearchConceptsChiral supramolecular assembliesStructural DNA nanotechnologyNatural d-DNACircular dichroism spectraSupramolecular assembliesDNA supramoleculesAtomic force microscopeDNA nanostructuresDNA nanotechnologyL-DNADichroism spectraVivo medical applicationsNuclease resistanceForce microscopePolyacrylamide gel electrophoresisOpposite chiralityNanostructuresD-DNAPeriodic nanostructuresMedical applicationsSupramoleculesGel electrophoresisSubstantial complementChiralityNanotechnologyIn vivo cloning of artificial DNA nanostructures
Lin C, Rinker S, Wang X, Liu Y, Seeman NC, Yan H. In vivo cloning of artificial DNA nanostructures. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 17626-17631. PMID: 18927233, PMCID: PMC2584761, DOI: 10.1073/pnas.0805416105.Peer-Reviewed Original ResearchMeSH KeywordsCloning, MolecularCross-Linking ReagentsDNADNA ReplicationFicusinNanostructuresNucleic Acid ConformationConceptsArtificial DNA nanostructuresDNA nanostructuresDNA nanotechnologyGenetic information carriersStandard molecular biology techniquesNanostructuresVersatile methodFour-arm junctionsVivo cloningMolecular biology techniquesNumber of assaysComplex secondary structureBiology techniquesNanotechnologyHigh copy numberLiving cellsFerguson analysisHelper phageCorrect replicationPossible solutionsSecondary structureCopy numberPhagemidCarriersDNASubtractive assembly of DNA nanoarchitectures driven by fuel strand displacement
Li Z, Ke Y, Lin C, Yan H, Liu Y. Subtractive assembly of DNA nanoarchitectures driven by fuel strand displacement. Chemical Communications 2008, 0: 4318-4320. PMID: 18802556, DOI: 10.1039/b807933a.Peer-Reviewed Original Research
2007
Rolling Circle Enzymatic Replication of a Complex Multi-Crossover DNA Nanostructure
Lin C, Wang X, Liu Y, Seeman NC, Yan H. Rolling Circle Enzymatic Replication of a Complex Multi-Crossover DNA Nanostructure. Journal Of The American Chemical Society 2007, 129: 14475-14481. PMID: 17963390, PMCID: PMC3319872, DOI: 10.1021/ja0760980.Peer-Reviewed Original Research
2006
DNA Tile Based Self‐Assembly: Building Complex Nanoarchitectures
Lin C, Liu Y, Rinker S, Yan H. DNA Tile Based Self‐Assembly: Building Complex Nanoarchitectures. ChemPhysChem 2006, 7: 1641-1647. PMID: 16832805, DOI: 10.1002/cphc.200600260.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBase CompositionBiophysicsDNALigandsMolecular ConformationNanocompositesNanoparticlesNanostructuresNanotechnologyNucleic Acid ConformationPhotonsProtein Array AnalysisProteinsConceptsDNA tilesSelf-assembled DNA nanostructuresNanometer-scale materialsNanometer-scale componentsComplex nanoarchitecturesDNA nanostructuresNanophotonic devicesAttractive routeExcellent scaffoldProgrammable patternsNanoarchitecturesPotential applicationsExciting progressNanoarraysNanoparticlesNanostructuresRecent developmentsScaffoldsDevicesRouteMaterials