2020
DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells
Williams ND, Landajuela A, Kasula RK, Zhou W, Powell JT, Xi Z, Isaacs FJ, Berro J, Toomre D, Karatekin E, Lin C. DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells. Nano Letters 2020, 20: 8890-8896. PMID: 33164530, PMCID: PMC7726105, DOI: 10.1021/acs.nanolett.0c03925.Peer-Reviewed Original ResearchConceptsCopies of proteinsBrightness standardsFluorescence microscopyProtein countingMammalian cellsFluorescent proteinCopy numberLive cellsConventional quantification techniquesBiological LaboratoryFluorescence microscopeProteinDNA origamiVersatile toolCellsBiologyCurrent quantification methodsCopiesOrganic dyes
2008
In vivo cloning of artificial DNA nanostructures
Lin C, Rinker S, Wang X, Liu Y, Seeman NC, Yan H. In vivo cloning of artificial DNA nanostructures. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 17626-17631. PMID: 18927233, PMCID: PMC2584761, DOI: 10.1073/pnas.0805416105.Peer-Reviewed Original ResearchConceptsArtificial DNA nanostructuresDNA nanostructuresDNA nanotechnologyGenetic information carriersStandard molecular biology techniquesNanostructuresVersatile methodFour-arm junctionsVivo cloningMolecular biology techniquesNumber of assaysComplex secondary structureBiology techniquesNanotechnologyHigh copy numberLiving cellsFerguson analysisHelper phageCorrect replicationPossible solutionsSecondary structureCopy numberPhagemidCarriersDNA