C. Patrick Lusk, PhD
Cards
About
Titles
Associate Professor of Cell Biology
Co-Director, Molecular Cell Biology, Genetics and Development Track, Cell Biology; Co-Director, Cellular, Molecular, and Quantitative Biology Training Program, Cell BiologyBiography
Dr. Lusk runs the joint LusKing laboratory with Megan King in the Department of Cell Biology. He is also the co-director of the MCGD graduate training track. He has a long standing interest in fundamental cellular mechanisms of compartmentalization with an emphasis on those that govern the biogenesis of the nuclear envelope and nuclear pore complexes (NPCs). He has been studying the nuclear envelope and nuclear transport since his graduate work at the University of Alberta in Canada and has been trained during his postdoctoral fellowship by Nobel Laureate Günter Blobel at The Rockefeller University. During this time, he (with collaborators/colleagues) has provided substantial insight into how nuclear transport is regulated and how the NPC is assembled. Moreover, he has helped to develop yeast as a model to study integral membrane proteins that reside at the inner nuclear membrane. While it is generally understood that these proteins are essential factors in gene regulation and genome organization, which is reflected by the discovery of the “nuclear envelopathies”, they remain challenging to study. Dr. Lusk is leveraging his expertise in yeast cell biology and genetics with super-resolution and proteomic approaches to illuminate function at the nuclear periphery.
Appointments
Cell Biology
Associate Professor TenurePrimary
Other Departments & Organizations
- Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS)
- Cell Biology
- Cell Biology Research
- Discovery to Cure Internship
- Genomics, Genetics, and Epigenetics
- LusKing Lab
- Molecular Cell Biology, Genetics and Development
- Yale Cancer Center
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale Ventures
Education & Training
- Postdoctoral Fellow
- The Rockefeller University (2009)
- PhD
- University of Alberta (2005)
- BS
- University of Alberta (1998)
Research
Overview
Medical Subject Headings (MeSH)
Links & Media
Media
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Superresolution image of nuclear pore complexes
News
- September 05, 2022Source: ASBMB Today
The importance of team mentorship
- February 07, 2021Source: BioRxiv
A DNA-origami NanoTrap for studying the diffusion barriers
- December 13, 2020Source: BioRxiv
The LusKing lab discovers role for phosphatidic acid in nuclear envelope surveillance
- February 12, 2020
In the right (lab) culture, mentorship flourishes — and science benefits
Get In Touch
Contacts
Cell Biology
PO Box 208002, 333 Cedar Street
New Haven, CT 06520-8002
United States
Locations
Boyer Center for Molecular Medicine
Lab
Boyer Center for Molecular Medicine
Academic Office