Yale Head and Neck SPORE CEP & DRP Symposium

Presentations by pilot project awardees:

• Michael Chiorazzi, MD, PhD (Yale) “Investigation of the HNSCC Tumor Microenvironment and Response to Therapy with Autologous Humanized”
• Jeffrey Ishizuka, MD, DPhil (Yale) “Overcoming inflammatory immune dysfunction in head and neck cancer"
• Megan King, PhD / Patrick Lusk, PhD (Yale) “Nuclear integrity as a novel modulator of the radiation response in head and neck cancer”
• Jong Woo Lee, PhD (Yale) “Regulation of autophagy to optimize AURKA inhibition-mediated therapeutics in head and neck cancer“
• Travis Schrank, MD, PhD (University of North Carolina) “Double-strand break repair deficiency as a driver of genomic copy number heterogeneity in HPV associated head and neck squamous cell carcinoma”
• Pedro Torres-Ayuso, PhD (Fox Chase Cancer Center) “Testing understudied kinase TNIK as a target in head and neck squamous cell carcinoma"
• He Wang, MD, PhD (Yale) “Electronic cigarette exposure on oral mucosa

carcinogenesis “