2017
Constructing Predictive Microbial Signatures at Multiple Taxonomic Levels
Wang T, Zhao H. Constructing Predictive Microbial Signatures at Multiple Taxonomic Levels. Journal Of The American Statistical Association 2017, 112: 1022-1031. DOI: 10.1080/01621459.2016.1270213.Peer-Reviewed Original ResearchBacterial taxaTaxonomic levelsMultiple taxonomic levelsDifferent taxonomic levelsDNA sequencing technologiesHuman microbiome studiesPhylogenetic treeHost phenotypeSequencing technologiesNormal human physiologyTaxaHuman microbiomeMicrobial signaturesMicrobiome studiesMicrobiome data analysisImportant groupMicrobiome dataHigh-dimensional compositional dataHuman physiologyRecent advancesMicrobesRapid advancesMajor goalMicrobiomePhenotype
2015
A Statistical Framework to Predict Functional Non-Coding Regions in the Human Genome Through Integrated Analysis of Annotation Data
Lu Q, Hu Y, Sun J, Cheng Y, Cheung KH, Zhao H. A Statistical Framework to Predict Functional Non-Coding Regions in the Human Genome Through Integrated Analysis of Annotation Data. Scientific Reports 2015, 5: 10576. PMID: 26015273, PMCID: PMC4444969, DOI: 10.1038/srep10576.Peer-Reviewed Original ResearchConceptsHuman genomeFunctional regionsStatistical frameworkAnnotation dataFunctional annotation dataWhole-genome annotationNon-coding regionsGenomic conservationHigh-throughput experimentsENCODE projectExperimental annotationsGenomeUnsupervised statistical learningFunctional potentialHuman geneticsStatistical learningComputational predictionsIntegrated analysisAnnotationAnnotation methodDiverse typesPowerful toolGeneticsMajor goalWeb server