2020
Association of Ticagrelor vs Clopidogrel With Net Adverse Clinical Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
You SC, Rho Y, Bikdeli B, Kim J, Siapos A, Weaver J, Londhe A, Cho J, Park J, Schuemie M, Suchard MA, Madigan D, Hripcsak G, Gupta A, Reich CG, Ryan PB, Park RW, Krumholz HM. Association of Ticagrelor vs Clopidogrel With Net Adverse Clinical Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. JAMA 2020, 324: 1640-1650. PMID: 33107944, PMCID: PMC7592033, DOI: 10.1001/jama.2020.16167.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAdultAgedAged, 80 and overAlgorithmsAspirinCase-Control StudiesCause of DeathClopidogrelDatabases, FactualDyspneaFemaleHemorrhageHumansIschemiaMaleMiddle AgedMyocardial InfarctionNetwork Meta-AnalysisPercutaneous Coronary InterventionPropensity ScorePurinergic P2Y Receptor AntagonistsRecurrenceRepublic of KoreaRetrospective StudiesStrokeTicagrelorUnited StatesConceptsNet adverse clinical eventsAcute coronary syndromePercutaneous coronary interventionAdverse clinical eventsHemorrhagic eventsIschemic eventsHazard ratioCause mortalityCoronary syndromeCoronary interventionClinical eventsRisk of NACEClinical practiceLarge randomized clinical trialsPrimary end pointRetrospective cohort studyPropensity-matched pairsSummary hazard ratioRandomized clinical trialsRoutine clinical practiceSignificant differencesP2Y12 platelet inhibitorsTicagrelor groupCohort studySecondary outcomes
2001
Symptom Predictors of Acute Coronary Syndromes in Younger and Older Patients
Milner K, Funk M, Richards S, Vaccarino V, Krumholz H. Symptom Predictors of Acute Coronary Syndromes in Younger and Older Patients. Nursing Research 2001, 50: 233-241. PMID: 11480532, DOI: 10.1097/00006199-200107000-00007.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeOlder patientsYounger patientsChest symptomsSymptom predictorsTypical symptomsCoronary syndromeRegional cardiac referral centerCardiac referral centerInitiation of treatmentLogistic regression analysisPositive predictorArm painReferral centerPatient ageAtypical symptomsEmergency departmentAppropriate triageBorderline associationSymptom presentPatient decisionGreater oddsPatientsSignificant negative predictorPatient's presence