2011
Use of Medical Imaging Procedures With Ionizing Radiation in Children: A Population-Based Study
Dorfman AL, Fazel R, Einstein AJ, Applegate KE, Krumholz HM, Wang Y, Christodoulou E, Chen J, Sanchez R, Nallamothu BK. Use of Medical Imaging Procedures With Ionizing Radiation in Children: A Population-Based Study. JAMA Pediatrics 2011, 165: 458-464. PMID: 21199972, PMCID: PMC3686496, DOI: 10.1001/archpediatrics.2010.270.Peer-Reviewed Original ResearchConceptsDiagnostic imaging proceduresTomographic scanImaging proceduresRetrospective cohort analysisPopulation-based ratesPediatric populationPlain radiographyCohort analysisHigh dosesMedical diagnostic imaging proceduresStudy periodAppropriate useChildrenHigh rateMedical imaging proceduresScansFrequent useHealth care marketUS health care marketYearsPatientsInfantsPopulationCare marketUnitedHealthcare
2009
Exposure to Low-Dose Ionizing Radiation from Medical Imaging Procedures
Fazel R, Krumholz HM, Wang Y, Ross JS, Chen J, Ting HH, Shah ND, Nasir K, Einstein AJ, Nallamothu BK. Exposure to Low-Dose Ionizing Radiation from Medical Imaging Procedures. New England Journal Of Medicine 2009, 361: 849-857. PMID: 19710483, PMCID: PMC3707303, DOI: 10.1056/nejmoa0901249.Peer-Reviewed Original ResearchConceptsCumulative effective dosesCumulative effective doseEffective dosesEffective doseMean cumulative effective doseImaging proceduresLow-dose ionizing radiationPopulation-based ratesMedian effective doseOutpatient settingGeneral populationHigh dosesUtilization dataDosesEnrolleesStudy periodRadiation exposureNuclear imagingDoseAnnual effective dosesMedical imaging proceduresUnited StatesExposureHealth care marketYears
2001
Angiotensin-converting enzyme inhibitor dosages in elderly patients with heart failure
Chen Y, Wang Y, Radford M, Krumholz H. Angiotensin-converting enzyme inhibitor dosages in elderly patients with heart failure. American Heart Journal 2001, 141: 410-417. PMID: 11231438, DOI: 10.1067/mhj.2001.113227.Peer-Reviewed Original ResearchConceptsACE inhibitorsHeart failureClinical trialsSystolic dysfunctionElderly patientsLow dosesConfirmed heart failureDosage of angiotensinRepresentative elderly cohortDose-response relationshipHospital dischargeClinical factorsGuideline recommendationsElderly cohortMedication dataMedical recordsAdministrative databasesConnecticut hospitalsPractice guidelinesEnzyme inhibitorsPatientsLower mortalityHigh dosesDosesMortality