2006
Underrepresentation of Renal Disease in Randomized Controlled Trials of Cardiovascular Disease
Coca SG, Krumholz HM, Garg AX, Parikh CR. Underrepresentation of Renal Disease in Randomized Controlled Trials of Cardiovascular Disease. JAMA 2006, 296: 1377-1384. PMID: 16985230, DOI: 10.1001/jama.296.11.1377.Peer-Reviewed Original ResearchConceptsChronic congestive heart failureCongestive heart failureRenal diseaseRenal functionHeart failureSubgroup analysisCardiovascular diseaseCardiology/American Heart Association guidelinesAmerican Heart Association guidelinesAldosterone system antagonistsBaseline renal functionHeart Association guidelinesCardiovascular disease trialsCurrent American CollegeRandomized Controlled TrialsAcute myocardial infarctionEffects of interventionsRepresentation of patientsOriginal articlesBaseline characteristicsCardiovascular mortalityPatient characteristicsControlled TrialsPrognostic featuresMyocardial infarction
2004
Hospital percutaneous coronary intervention volume and patient mortality, 1998 to 2000 Does the evidence support current procedure volume minimums?
Epstein AJ, Rathore SS, Volpp KG, Krumholz HM. Hospital percutaneous coronary intervention volume and patient mortality, 1998 to 2000 Does the evidence support current procedure volume minimums? Journal Of The American College Of Cardiology 2004, 43: 1755-1762. PMID: 15145095, PMCID: PMC2803067, DOI: 10.1016/j.jacc.2003.09.070.Peer-Reviewed Original ResearchConceptsHigh-volume hospitalsMedium-volume hospitalsLow-volume hospitalsHospital mortalityHigh PCI volume hospitalsPercutaneous coronary intervention volumeACC/AHA guidelinesProcedure-associated mortalityHospital mortality rateCurrent American CollegeHospital discharge databaseAnnual PCI volumesVolume hospitalsAHA guidelinesPatient characteristicsPCI volumePatient mortalityDischarge databaseIntervention volumeRetrospective analysisAmerican CollegeComparable riskMortality ratePatientsHospital