2019
Interplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality The CAC Consortium
Grandhi GR, Mirbolouk M, Dardari ZA, Al-Mallah MH, Rumberger JA, Shaw LJ, Blankstein R, Miedema MD, Berman DS, Budoff MJ, Krumholz HM, Blaha MJ, Nasir K. Interplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality The CAC Consortium. JACC Cardiovascular Imaging 2019, 13: 1175-1186. PMID: 31734198, DOI: 10.1016/j.jcmg.2019.08.024.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCause of DeathComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseDiabetes MellitusDyslipidemiasFemaleHeart Disease Risk FactorsHumansHypertensionMaleMiddle AgedMultidetector Computed TomographyPredictive Value of TestsPrevalencePrognosisRetrospective StudiesRisk AssessmentSmokingTime FactorsUnited StatesVascular CalcificationConceptsCoronary artery calciumCoronary heart diseaseRisk factorsCause-specific mortalityRF burdenCause mortalityArtery calciumCAC scoreCVD mortalityAbsence of CACHigher CAC scoresCHD mortality ratesCurrent cigarette smokingCardiovascular disease deathsCAC ConsortiumCAC testingMulticenter cohortCigarette smokingDisease deathsHeart diseasePrognostic informationBaseline riskFamily historyMost deathsMortality rateDevelopment and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention
Huang C, Li SX, Mahajan S, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention. JAMA Network Open 2019, 2: e1916021. PMID: 31755952, PMCID: PMC6902830, DOI: 10.1001/jamanetworkopen.2019.16021.Peer-Reviewed Original ResearchConceptsCreatinine level increaseAcute kidney injuryPercutaneous coronary interventionContrast volumeAKI riskKidney injuryCoronary interventionBaseline riskCardiology National Cardiovascular Data Registry's CathPCI RegistryNational Cardiovascular Data Registry CathPCI RegistryRisk of AKIAcute Kidney Injury AssociatedDifferent baseline risksPCI safetyCathPCI RegistryInjury AssociatedMean ageDerivation setPreprocedural riskMAIN OUTCOMEAmerican CollegePrognostic studiesUS hospitalsCalibration slopeValidation set
2008
Cerebrovascular Disease Risk in Older Head and Neck Cancer Patients After Radiotherapy
Smith GL, Smith BD, Buchholz TA, Giordano SH, Garden AS, Woodward WA, Krumholz HM, Weber RS, Ang K, Rosenthal DI. Cerebrovascular Disease Risk in Older Head and Neck Cancer Patients After Radiotherapy. Journal Of Clinical Oncology 2008, 26: 5119-5125. PMID: 18725647, PMCID: PMC4879715, DOI: 10.1200/jco.2008.16.6546.Peer-Reviewed Original ResearchConceptsCerebrovascular disease riskNeck cancer patientsDisease riskCerebrovascular eventsCerebrovascular riskCardiac riskCancer patientsNeck cancerTreatment groupsTen-year incidenceProportional hazards regressionDefinitive radiotherapyPostoperative radiotherapyCardiac eventsOlder patientsCerebrovascular diseaseHazards regressionNonmetastatic headMean ageVascular diseaseBaseline riskPatientsSurgeryRadiotherapyControl diagnosisRegional Variation in Cardiac Catheterization Appropriateness and Baseline Risk After Acute Myocardial Infarction
Ko DT, Wang Y, Alter DA, Curtis JP, Rathore SS, Stukel TA, Masoudi FA, Ross JS, Foody JM, Krumholz HM. Regional Variation in Cardiac Catheterization Appropriateness and Baseline Risk After Acute Myocardial Infarction. Journal Of The American College Of Cardiology 2008, 51: 716-723. PMID: 18279735, DOI: 10.1016/j.jacc.2007.10.039.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac catheterization useBaseline riskCardiac catheterizationMyocardial infarctionCardiology/American Heart Association classificationRisk-standardized mortality ratesAmerican Heart Association classificationCardiac catheterization ratesGRACE risk scoreHigh-risk patientsClass I patientsClass III patientsClass II patientsPatient appropriatenessCatheterization ratesHospital admissionI patientsPrimary outcomeAMI patientsII patientsIII patientsAppropriate indicationsInvasive strategyPhysician characteristics
2006
Effect of Door-to-Balloon Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
McNamara RL, Wang Y, Herrin J, Curtis JP, Bradley EH, Magid DJ, Peterson ED, Blaney M, Frederick PD, Krumholz HM, Investigators N. Effect of Door-to-Balloon Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction. Journal Of The American College Of Cardiology 2006, 47: 2180-2186. PMID: 16750682, DOI: 10.1016/j.jacc.2005.12.072.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionBalloon timeElevation myocardial infarctionSymptom onsetMyocardial infarctionHospital mortalityPatient characteristicsDoor timeEffect of doorPrimary PCIBaseline risk statusPercutaneous coronary interventionHigh-risk factorsSTEMI patientsCohort studyCoronary interventionLonger doorEntire cohortSubgroup analysisNational registryBaseline riskMortality riskPatientsMortality