2008
Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM
Crawford FW, Khayal IS, McGue C, Saraswathy S, Pirzkall A, Cha S, Lamborn KR, Chang SM, Berger MS, Nelson SJ. Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM. Journal Of Neuro-Oncology 2008, 91: 337. PMID: 19009235, PMCID: PMC3022444, DOI: 10.1007/s11060-008-9719-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAspartic AcidBrain MappingBrain NeoplasmsCholineCreatineDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleGlioblastomaHumansImage EnhancementImage Processing, Computer-AssistedKaplan-Meier EstimateLactic AcidLipidsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedProtonsRadionuclide ImagingRetrospective StudiesConceptsGlioblastoma multiformeApparent diffusion coefficientPoor survivalConventional anatomical MR imagingAnatomical MR imagingUntreated glioblastoma multiformeT2 hyperintense lesionsMedian survival timeLow-risk groupBlood-brain barrierStratification of patientsContrast-enhancing lesionsPerfusion-weighted imagingDiffusion-weighted imagingPhysiological MRProton MR spectroscopicFavorable survivalSurgical resectionT2 lesionsHyperintense lesionsPrognostic valueBrain barrierElevated cholineClinical trialsLesion volume
2005
Relationship of MR-derived lactate, mobile lipids, and relative blood volume for gliomas in vivo.
Li X, Vigneron DB, Cha S, Graves EE, Crawford F, Chang SM, Nelson SJ. Relationship of MR-derived lactate, mobile lipids, and relative blood volume for gliomas in vivo. American Journal Of Neuroradiology 2005, 26: 760-9. PMID: 15814918, PMCID: PMC7977113.Peer-Reviewed Original ResearchConceptsRelative cerebral blood volumeHigh-grade gliomasBiopsy/resectionBlood volumeLow-grade patientsDynamic susceptibility contrast MR imagingCerebral blood volumeRelative blood volumePerfusion-weighted imagesElevated lipsAppropriate therapyMR spectroscopic imagingSurgical biopsyMobile lipidsRCBV mapsPatientsGliomasResectionHeterogeneous tumorsRadiation treatmentMR imagingVivo distributionLipMR spectroscopic imagesVivo