Publications

Li F, Sewald X, Jin J, Sherer NM and Mothes W: Murine leukemia virus gag localizes to the uropod of migrating primary lymphocytes. J Virol. 2014 Sep 15;88 (18) :10541-55. Epub 2014 Jun 25. PMID: 24965475


Uchil PD, Pawliczek T, Reynolds TD, Ding S, Hinz A, Munro J, Huang F, Floyd RW, Yang H, Hamilton W, Bewersdorf J, Xiong Y, Calderwood DA and Mothes W: TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly. J Cell Sci. 2014 Jul 11; Epub 2014 Jul 11. PMID: 25015296


Munro JB and Mothes W: The HIV-1 Env trimer in HD. Structure. 2014 Jul 8;22 (7) :935-6. PMID: 25007222


Munro JB, Nath A, Färber M, Datta SA, Rein A, Rhoades E and Mothes W: A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles. J Virol. 2014 Mar;88 (6) :3577-85. Epub 2014 Jan 8. PMID: 24403576


Agosto LM, Zhong P, Munro J and Mothes W: Highly active antiretroviral therapies are effective against HIV-1 cell-to-cell transmission. PLoS Pathog. 2014 Feb;10 (2) :e1003982. Epub 2014 Feb 27. PMID: 24586176

Huang F, Hartwich TM, Rivera-Molina FE, Lin Y, Duim WC, Long JJ, Uchil PD, Myers JR, Baird MA, Mothes W, Davidson MW, Toomre D and Bewersdorf J: Video-rate nanoscopy using sCMOS camera-specific single-molecule localization algorithms. Nat Methods. 2013 Jul;10 (7) :653-8. Epub 2013 May 26. PMID: 23708387


Li F, Jin J, Herrmann C and Mothes W: Basic residues in the matrix domain and multimerization target murine leukemia virus Gag to the virological synapse. J Virol. 2013 Jun;87 (12) :7113-26. Epub 2013 Apr 24. PMID: 23616653


Zhong P, Agosto LM, Munro JB and Mothes W: Cell-to-cell transmission of viruses. Curr Opin Virol. 2013 Feb;3 (1) :44-50. Epub 2012 Dec 5. PMID: 23219376


Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J and Mothes W: TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013 Jan;87 (1) :257-72. Epub 2012 Oct 17. PMID: 23077300


Garcia ML, Reynolds TD, Mothes W and Robek MD: Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras. PLoS One. 2013;8 (8) :e72845. Epub 2013 Aug 29. PMID: 24009707


Zhong P, Agosto LM, Ilinskaya A, Dorjbal B, Truong R, Derse D, Uchil PD, Heidecker G and Mothes W: Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV. PLoS One. 2013;8 (1) :e53138. Epub 2013 Jan 7. PMID: 23308151

Sewald X, Gonzalez DG, Haberman AM and Mothes W: In vivo imaging of virological synapses. Nat Commun. 2012;3 :1320. PMID: 23271654

Jin J, Li F and Mothes W: Viral determinants of polarized assembly for the murine leukemia virus. J Virol. 2011 Aug;85 (15) :7672-82. Epub 2011 May 18. PMID: 21593177


Kajaste-Rudnitski A, Marelli SS, Pultrone C, Pertel T, Uchil PD, Mechti N, Mothes W, Poli G, Luban J and Vicenzi E: TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements. J Virol. 2011 May;85 (10) :5183-96. Epub 2011 Feb 23. PMID: 21345949


Pertel T, Hausmann S, Morger D, Züger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, Grütter MG and Luban J: TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature. 2011 Apr 21;472 (7343) :361-5. PMID: 21512573

Mothes W, Sherer NM, Jin J and Zhong P: Virus cell-to-cell transmission. J Virol. 2010 Sep;84 (17) :8360-8. Epub 2010 Apr 7. PMID: 20375157


Sherer NM, Jin J and Mothes W: Directional spread of surface-associated retroviruses regulated by differential virus-cell interactions. J Virol. 2010 Apr;84 (7) :3248-58. Epub 2010 Jan 20. PMID: 20089647


Jin J, Sherer N and Mothes W: Surface Transmission or Polarized Egress? Lessons Learned from HTLV Cell-to-Cell Transmission. Viruses. 2010 Feb;2 (2) :601-5. Epub 2010 Feb 10. PMID: 21994650

Jin J, Sturgeon T, Weisz OA, Mothes W and Montelaro RC: HIV-1 matrix dependent membrane targeting is regulated by Gag mRNA trafficking. PLoS One. 2009 Aug 7;4 (8) :e6551. Epub 2009 Aug 7. PMID: 19662089


Jin J, Sherer NM, Heidecker G, Derse D and Mothes W: Assembly of the murine leukemia virus is directed towards sites of cell-cell contact. PLoS Biol. 2009 Jul;7 (7) :e1000163. Epub 2009 Jul 28. PMID: 19636361


Uchil PD and Mothes W: HIV Entry Revisited. Cell. 2009 May 1;137 (3) :402-4. PMID: 19410537


Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F and Greene WC: The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol. 2009 Jan;83 (1) :73-80. Epub 2008 Oct 22. PMID: 18945786


Carthagena L, Bergamaschi A, Luna JM, David A, Uchil PD, Margottin-Goguet F, Mothes W, Hazan U, Transy C, Pancino G and Nisole S: Human TRIM gene expression in response to interferons. PLoS One. 2009;4 (3) :e4894. Epub 2009 Mar 17. PMID: 19290053

Chan R, Uchil PD, Jin J, Shui G, Ott DE, Mothes W and Wenk MR: Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides. J Virol. 2008 Nov;82 (22) :11228-38. Epub 2008 Sep 17. PMID: 18799574


Sherer NM and Mothes W: Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis. Trends Cell Biol. 2008 Sep;18 (9) :414-20. Epub 2008 Aug 14. PMID: 18703335


Chan WT, Sherer NM, Uchil PD, Novak EK, Swank RT and Mothes W: Murine leukemia virus spreading in mice impaired in the biogenesis of secretory lysosomes and Ca2+-regulated exocytosis. PLoS One. 2008 Jul 16;3 (7) :e2713. Epub 2008 Jul 16. PMID: 18629000


Uchil PD, Quinlan BD, Chan WT, Luna JM and Mothes W: TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. PLoS Pathog. 2008 Feb 8;4 (2) :e16. PMID: 18248090

Münch J, Rücker E, Ständker L, Adermann K, Goffinet C, Schindler M, Wildum S, Chinnadurai R, Rajan D, Specht A, Giménez-Gallego G, Sánchez PC, Fowler DM, Koulov A, Kelly JW, Mothes W, Grivel JC, Margolis L, Keppler OT, Forssmann WG and Kirchhoff F: Semen-derived amyloid fibrils drastically enhance HIV infection. Cell. 2007 Dec 14;131 (6) :1059-71. PMID: 18083097


Stahl S, Reinders Y, Asan E, Mothes W, Conzelmann E, Sickmann A and Felbor U: Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes. Biochim Biophys Acta. 2007 Oct;1774 (10) :1237-46. Epub 2007 Jul 19. PMID: 17765022


Sherer NM, Lehmann MJ, Jimenez-Soto LF, Horensavitz C, Pypaert M and Mothes W: Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission. Nat Cell Biol. 2007 Mar;9 (3) :310-5. Epub 2007 Feb 11. PMID: 17293854

Czibener C, Sherer NM, Becker SM, Pypaert M, Hui E, Chapman ER, Mothes W and Andrews NW: Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes. J Cell Biol. 2006 Sep 25;174 (7) :997-1007. Epub 2006 Sep 18. PMID: 16982801

Lehmann MJ, Sherer NM, Marks CB, Pypaert M and Mothes W: Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells. J Cell Biol. 2005 Jul 18;170 (2) :317-25. PMID: 16027225


Uchil P and Mothes W: Viral entry: a detour through multivesicular bodies. Nat Cell Biol. 2005 Jul;7 (7) :641-2. PMID: 15990891


Melikyan GB, Barnard RJ, Abrahamyan LG, Mothes W and Young JA: Imaging individual retroviral fusion events: from hemifusion to pore formation and growth. Proc Natl Acad Sci U S A. 2005 Jun 14;102 (24) :8728-33. Epub 2005 Jun 3. PMID: 15937118

Sherer NM, Lehmann MJ, Jimenez-Soto LF, Ingmundson A, Horner SM, Cicchetti G, Allen PG, Pypaert M, Cunningham JM and Mothes W: Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. Traffic. 2003 Nov;4 (11) :785-801. PMID: 14617360

Felbor U, Kessler B, Mothes W, Goebel HH, Ploegh HL, Bronson RT and Olsen BR: Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci U S A. 2002 Jun 11;99 (12) :7883-8. Epub 2002 Jun 4. PMID: 12048238

Mothes W, Boerger AL, Narayan S, Cunningham JM and Young JA: Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell. 2000 Nov 10;103 (4) :679-89. PMID: 11106737