Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.

Condello C, Yuan P, Schain A, Grutzendler J.

Nat Commun. 2015 Jan 29;6 :6176. Epub 2015 Jan 29. PMID: 25630253


In vivo imaging of oligodendrocytes with sulforhodamine 101.

Hill RA, Grutzendler J.

Nat Methods. 2014 Nov;11 (11) :1081-2. PMID: 25357236


Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division.

Hill RA, Patel KD, Goncalves CM, Grutzendler J, Nishiyama A.

Nat Neurosci. 2014 Nov;17 (11) :1518-27. Epub 2014 Sep 28. PMID: 25262495


A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease.

Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C.

Chem Commun (Camb). 2014 Oct 9;50 (78) :11550-3. PMID: 25134928


Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy.

Schain AJ, Hill RA, Grutzendler J.

Nat Med. 2014 Apr;20 (4) :443-9. Epub 2014 Mar 30. PMID: 24681598


Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation.

Grutzendler J, Murikinati S, Hiner B, Ji L, Lam CK, Yoo T, Gupta S, Hafler BP, Adelman RA, Yuan P, Rodriguez G.

Sci Transl Med. 2014 Mar 5;6 (226) :226ra31. PMID: 24598589


Angiophagy: clearing or clogging microvessels?

Iadecola C.

Sci Transl Med. 2014 Mar 5;6 (226) :226fs10. PMID: 24598587


Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period.

Whiteus C, Freitas C, Grutzendler J.

Nature. 2014 Jan 16;505 (7483) :407-11. Epub 2013 Dec 4. PMID: 24305053


Angiophagy: mechanism of microvascular recanalization independent of the fibrinolytic system.

Grutzendler J.

Stroke. 2013 Jun;44 (6 Suppl 1) :S84-6. PMID: 23709741


In vivo imaging of cerebral microvascular plasticity from birth to death.

Harb R, Whiteus C, Freitas C, Grutzendler J.

J Cereb Blood Flow Metab. 2013 Jan;33 (1) :146-56. Epub 2012 Oct 24. PMID: 23093067


Transcranial two-photon imaging of the living mouse brain.

Grutzendler J, Yang G, Pan F, Parkhurst CN, Gan WB.

Cold Spring Harb Protoc. 2011 Sep 1;2011 (9) Epub 2011 Sep 1. PMID: 21880826


Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition.

Condello C, Schain A, Grutzendler J.

Sci Rep. 2011;1 :19. Epub 2011 Jun 21. PMID: 22355538


CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis.

Liu Z, Condello C, Schain A, Harb R, Grutzendler J.

J Neurosci. 2010 Dec 15;30 (50) :17091-101. PMID: 21159979


Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization.

Lam CK, Yoo T, Hiner B, Liu Z, Grutzendler J.

Nature. 2010 May 27;465 (7297) :478-82. PMID: 20505729


Thinned-skull cranial window technique for long-term imaging of the cortex in live mice.

Yang G, Pan F, Parkhurst CN, Grutzendler J, Gan WB.

Nat Protoc. 2010 Feb;5 (2) :201-8. Epub 2010 Jan 14. PMID: 20134419


Ballistic delivery of dyes for structural and functional studies of the nervous system.

Gan WB, Grutzendler J, Wong RO, Lichtman JW.

Cold Spring Harb Protoc. 2009 Apr;2009 (4) :pdb.prot5202. PMID: 20147144


Long-term two-photon transcranial imaging of synaptic structures in the living brain.

Grutzendler J, Gan WB.

CSH Protoc. 2007 Jul 1;2007 :pdb.prot4766. Epub 2007 Jul 1. PMID: 21357119


Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease.

Grutzendler J, Helmin K, Tsai J, Gan WB.

Ann N Y Acad Sci. 2007 Feb;1097 :30-9. PMID: 17413007


Two-photon imaging of synaptic plasticity and pathology in the living mouse brain.

Grutzendler J, Gan WB.

NeuroRx. 2006 Oct;3 (4) :489-96. PMID: 17012063


ATP mediates rapid microglial response to local brain injury in vivo.

Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, Littman DR, Dustin ML, Gan WB.

Nat Neurosci. 2005 Jun;8 (6) :752-8. Epub 2005 May 15. PMID: 15895084


Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

Tsai J, Grutzendler J, Duff K, Gan WB.

Nat Neurosci. 2004 Nov;7 (11) :1181-3. Epub 2004 Oct 10. PMID: 15475950


Age-associated synapse elimination in mouse parasympathetic ganglia.

Coggan JS, Grutzendler J, Bishop DL, Cook MR, Gan W, Heym J, Lichtman JW.

J Neurobiol. 2004 Aug;60 (2) :214-26. PMID: 15266652


Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes.

Grutzendler J, Tsai J, Gan WB.

Methods. 2003 May;30 (1) :79-85. PMID: 12695105


Long-term dendritic spine stability in the adult cortex.

Grutzendler J, Kasthuri N, Gan WB.

Nature. 2002 Dec 19-26;420 (6917) :812-6. PMID: 12490949


Two modes of radial migration in early development of the cerebral cortex.

Nadarajah B, Brunstrom JE, Grutzendler J, Wong RO, Pearlman AL.

Nat Neurosci. 2001 Feb;4 (2) :143-50. PMID: 11175874


Cholinesterase inhibitors for Alzheimer's disease.

Grutzendler J, Morris JC.

Drugs. 2001;61 (1) :41-52. PMID: 11217870


Multicolor "DiOlistic" labeling of the nervous system using lipophilic dye combinations.

Gan WB, Grutzendler J, Wong WT, Wong RO, Lichtman JW.

Neuron. 2000 Aug;27 (2) :219-25. PMID: 10985343