Grutzendler, Jaime

Associate Professor of Neurology and of Neurobiology; Director, Yale Center for Experimental Neuroimaging (YCEN)

Biography

Dr. Grutzendler obtained his MD at Universidad Javeriana in Bogota, Colombia where he was born and raised. He completed a medical internship in Internal Medicine and a residency in Neurology at Washington University/Barnes-Jewish Hospital in St. Louis. This was followed by a combined clinical and research fellowship in the Alzheimer Disease Research Center and the Department of Neurobiology at Washington University and further neurobiology research training at the Skirball Institute of New...

Dr. Grutzendler obtained his MD at Universidad Javeriana in Bogota, Colombia where he was born and raised. He completed a medical internship in Internal Medicine and a residency in Neurology at Washington University/Barnes-Jewish Hospital in St. Louis. This was followed by a combined clinical and research fellowship in the Alzheimer Disease Research Center and the Department of Neurobiology at Washington University and further neurobiology research training at the Skirball Institute of New York University.
His research laboratory is interested in understanding various aspects of brain development and pathology using in vivo disease models. One area of interest is the development and pathology of the microvasculature and the "neuro-glio-vascular unit"(NGVU), neurovascular coupling, tissue oxygenation. The lab uses optical imaging techniques to better understand the dynamic behavior of cells within the NGVU (neurons, endothelium, astrocytes, pericytes, microglia and oligodendrocytes), how these cells interact with each other and how interactions are disrupted in injury,vascular and neurodegenerative disorders. Dr. Grutzendler's clinical interests focus on neurodegenerative disorders with special emphasis in dementias such as Alzheimer's disease.

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