Publications

Zeng W, Su M, Anderson KS and Sasada T: Artificial antigen-presenting cells expressing CD80, CD70, and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens. Immunobiology. 2014 Aug;219 (8) :583-92. Epub 2014 Mar 20. PMID: 24713579


Mislak AC, Frey KM, Bollini M, Jorgensen WL and Anderson KS: A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase. Biochim Biophys Acta. 2014 Jul;1840 (7) :2203-11. Epub 2014 Apr 12. PMID: 24726448


Towle-Weicksel JB, Dalal S, Sohl CD, Doublié S, Anderson KS and Sweasy JB: Fluorescence Resonance Energy Transfer Studies of DNA Polymerase β: THE CRITICAL ROLE OF FINGERS DOMAIN MOVEMENTS AND A NOVEL NON-COVALENT STEP DURING NUCLEOTIDE SELECTION. J Biol Chem. 2014 Jun 6;289 (23) :16541-50. Epub 2014 Apr 24. PMID: 24764311


Johnson DH, Khanna S, Smyrk TC, Loftus EV Jr, Anderson KS, Mahoney DW, Ahlquist DA and Kisiel JB: Detection rate and outcome of colonic serrated epithelial changes in patients with ulcerative colitis or Crohn's colitis. Aliment Pharmacol Ther. 2014 Jun;39 (12) :1408-17. Epub 2014 Apr 30. PMID: 24779703


Muftuoglu Y, Sohl CD, Mislak AC, Mitsuya H, Sarafianos SG and Anderson KS: Probing the molecular mechanism of action of the HIV-1 reverse transcriptase inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) using pre-steady-state kinetics. Antiviral Res. 2014 Jun;106 :1-4. Epub 2014 Mar 12. PMID: 24632447


Frey KM, Gray WT, Spasov KA, Bollini M, Gallardo-Macias R, Jorgensen WL and Anderson KS: Structure-based evaluation of C5 derivatives in the catechol diether series targeting HIV-1 reverse transcriptase. Chem Biol Drug Des. 2014 May;83 (5) :541-9. Epub 2014 Mar 14. PMID: 24289305


D'Souza G, Gross ND, Pai SI, Haddad R, Anderson KS, Rajan S, Gerber J, Gillison ML and Posner MR: Oral Human Papillomavirus (HPV) Infection in HPV-Positive Patients With Oropharyngeal Cancer and Their Partners. J Clin Oncol. 2014 Apr 28; Epub 2014 Apr 28. PMID: 24778397


Sharma H, Landau MJ, Sullivan TJ, Kumar VP, Dahlgren MK, Jorgensen WL and Anderson KS: Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase. Bioorg Med Chem Lett. 2014 Feb 15;24 (4) :1232-5. Epub 2013 Dec 31. PMID: 24440298


Siufi Neto J, Kho RM, Siufi DF, Baracat EC, Anderson KS and Abrão MS: Cellular, histologic, and molecular changes associated with endometriosis and ovarian cancer. J Minim Invasive Gynecol. 2014 Jan-Feb;21 (1) :55-63. Epub 2013 Aug 17. PMID: 23962574

Iyidogan P, Sullivan TJ, Chordia MD, Frey KM and Anderson KS: Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase. ACS Med Chem Lett. 2013 Dec 12;4 (12) :1183-8. Epub 2013 Oct 15. PMID: 24900627


Khan IM, Ahn W, Anderson KS and De S: A Logarithmic Complexity Floating Frame of Reference Formulation with Interpolating Splines for Articulated Multi-Flexible-Body Dynamics. Int J Non Linear Mech. 2013 Dec;57 :146-153. PMID: 24124265


Lee WG, Gallardo-Macias R, Frey KM, Spasov KA, Bollini M, Anderson KS and Jorgensen WL: Picomolar inhibitors of HIV reverse transcriptase featuring bicyclic replacement of a cyanovinylphenyl group. J Am Chem Soc. 2013 Nov 6;135 (44) :16705-13. Epub 2013 Oct 24. PMID: 24151856


Sharma H, Landau MJ, Vargo MA, Spasov KA and Anderson KS: First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling. Biochemistry. 2013 Oct 15;52 (41) :7305-17. Epub 2013 Oct 3. PMID: 24053355


Zaware N, Sharma H, Yang J, Devambatla RK, Queener SF, Anderson KS and Gangjee A: Discovery of potent and selective inhibitors of <i>Toxoplasma gondii</i> thymidylate synthase for opportunistic infections. ACS Med Chem Lett. 2013 Oct 4;4 (12) :1148-1151. PMID: 24470841


Kumar VP, Frey KM, Wang Y, Jain HK, Gangjee A and Anderson KS: Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitors. Bioorg Med Chem Lett. 2013 Oct 1;23 (19) :5426-8. Epub 2013 Jul 24. PMID: 23927969


Bollini M, Cisneros JA, Spasov KA, Anderson KS and Jorgensen WL: Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility. Bioorg Med Chem Lett. 2013 Sep 15;23 (18) :5213-6. Epub 2013 Jul 8. PMID: 23937980


Bollini M, Frey KM, Cisneros JA, Spasov KA, Das K, Bauman JD, Arnold E, Anderson KS and Jorgensen WL: Extension into the entrance channel of HIV-1 reverse transcriptase--crystallography and enhanced solubility. Bioorg Med Chem Lett. 2013 Sep 15;23 (18) :5209-12. Epub 2013 Jul 8. PMID: 23899617


Takahashi PY, Ryu E, Olson JE, Anderson KS, Hathcock MA, Haas LR, Naessens JM, Pathak J, Bielinski SJ and Cerhan JR: Hospitalizations and emergency department use in Mayo Clinic Biobank participants within the employee and community health medical home. Mayo Clin Proc. 2013 Sep;88 (9) :963-9. PMID: 24001488


Olson JE, Ryu E, Johnson KJ, Koenig BA, Maschke KJ, Morrisette JA, Liebow M, Takahashi PY, Fredericksen ZS, Sharma RG, Anderson KS, Hathcock MA, Carnahan JA, Pathak J, Lindor NM, Beebe TJ, Thibodeau SN and Cerhan JR: The Mayo Clinic Biobank: a building block for individualized medicine. Mayo Clin Proc. 2013 Sep;88 (9) :952-62. PMID: 24001487


Martucci WE, Rodriguez JM, Vargo MA, Marr M, Hamilton AD and Anderson KS: Exploring novel strategies for AIDS protozoal pathogens: α-helix mimetics targeting a key allosteric protein-protein interaction in <i>C. hominis</i> TS-DHFR. Medchemcomm. 2013 Sep;4 (9) PMID: 24324854


J Landau M, Sharma H and Anderson KS: Selective peptide inhibitors of bifunctional thymidylate synthase-dihydrofolate reductase from Toxoplasma gondii provide insights into domain-domain communication and allosteric regulation. Protein Sci. 2013 Sep;22 (9) :1161-73. Epub 2013 Aug 1. PMID: 23813474


Iyidogan P and Anderson KS: Recent findings on the mechanisms involved in tenofovir resistance. Antivir Chem Chemother. 2013 Jun 6; Epub 2013 Jun 6. PMID: 23744599


Wang J, Barker K, Steel J, Park J, Saul J, Festa F, Wallstrom G, Yu X, Bian X, Anderson KS, Figueroa JD, LaBaer J and Qiu J: A versatile protein microarray platform enabling antibody profiling against denatured proteins. Proteomics Clin Appl. 2013 Jun;7 (5-6) :378-83. Epub 2013 May 17. PMID: 23027520


Bailey CM, Sullivan TJ, Iyidogan P, Tirado-Rives J, Chung R, Ruiz-Caro J, Mohamed E, Jorgensen WL, Hunter R and Anderson KS: Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy. J Med Chem. 2013 May 23;56 (10) :3959-68. Epub 2013 May 9. PMID: 23659183


Wallstrom G, Anderson KS and LaBaer J: Biomarker discovery for heterogeneous diseases. Cancer Epidemiol Biomarkers Prev. 2013 May;22 (5) :747-55. Epub 2013 Mar 5. PMID: 23462916


Sohl CD, Kasiviswanathan R, Copeland WC and Anderson KS: Mutations in human DNA polymerase γ confer unique mechanisms of catalytic deficiency that mirror the disease severity in mitochondrial disorder patients. Hum Mol Genet. 2013 Mar 15;22 (6) :1074-85. Epub 2012 Dec 3. PMID: 23208208


Piao D, Basavapathruni A, Iyidogan P, Dai G, Hinz W, Ray AS, Murakami E, Feng JY, You F, Dutschman GE, Austin DJ, Parker KA and Anderson KS: Bifunctional inhibition of HIV-1 reverse transcriptase: a first step in designing a bifunctional triphosphate. Bioorg Med Chem Lett. 2013 Mar 1;23 (5) :1511-8. Epub 2012 Dec 20. PMID: 23380374


Bollini M, Gallardo-Macias R, Spasov KA, Tirado-Rives J, Anderson KS and Jorgensen WL: Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency. Bioorg Med Chem Lett. 2013 Feb 15;23 (4) :1110-3. Epub 2012 Dec 12. PMID: 23298809

Frey KM, Bollini M, Mislak AC, Cisneros JA, Gallardo-Macias R, Jorgensen WL and Anderson KS: Crystal structures of HIV-1 reverse transcriptase with picomolar inhibitors reveal key interactions for drug design. J Am Chem Soc. 2012 Dec 5;134 (48) :19501-3. Epub 2012 Nov 19. PMID: 23163887


Anderson KS and Segars JH: Predicting fertility with antimüllerian hormone: is a cutoff value adequate? Fertil Steril. 2012 Dec;98 (6) :1421-2. Epub 2012 Oct 1. PMID: 23036803


Iyidogan P and Anderson KS: Understanding the molecular mechanism of sequence dependent tenofovir removal by HIV-1 reverse transcriptase: differences in primer binding site versus polypurine tract. Antiviral Res. 2012 Aug;95 (2) :93-103. Epub 2012 Jun 1. PMID: 22664235


Sohl CD, Kasiviswanathan R, Kim J, Pradere U, Schinazi RF, Copeland WC, Mitsuya H, Baba M and Anderson KS: Balancing antiviral potency and host toxicity: identifying a nucleotide inhibitor with an optimal kinetic phenotype for HIV-1 reverse transcriptase. Mol Pharmacol. 2012 Jul;82 (1) :125-33. Epub 2012 Apr 18. PMID: 22513406


Kim Y, Li Z, Apetri M, Luo B, Settleman JE and Anderson KS: Temporal resolution of autophosphorylation for normal and oncogenic forms of EGFR and differential effects of gefitinib. Biochemistry. 2012 Jun 26;51 (25) :5212-22. Epub 2012 Jun 13. PMID: 22657099


Kim J, Wang L, Li Y, Becnel KD, Frey KM, Garforth SJ, Prasad VR, Schinazi RF, Liotta DC and Anderson KS: Pre-steady state kinetic analysis of cyclobutyl derivatives of 2'-deoxyadenosine 5'-triphosphate as inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2012 Jun 15;22 (12) :4064-7. Epub 2012 Apr 24. PMID: 22595174


Yu TY, Mok KC, Kennedy KJ, Valton J, Anderson KS, Walker GC and Taga ME: Active site residues critical for flavin binding and 5,6-dimethylbenzimidazole biosynthesis in the flavin destructase enzyme BluB. Protein Sci. 2012 Jun;21 (6) :839-49. Epub 2012 Apr 23. PMID: 22528544


Sohl CD, Singh K, Kasiviswanathan R, Copeland WC, Mitsuya H, Sarafianos SG and Anderson KS: Mechanism of interaction of human mitochondrial DNA polymerase γ with the novel nucleoside reverse transcriptase inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine indicates a low potential for host toxicity. Antimicrob Agents Chemother. 2012 Mar;56 (3) :1630-4. Epub 2011 Dec 12. PMID: 22155823


Ekkati AR, Bollini M, Domaoal RA, Spasov KA, Anderson KS and Jorgensen WL: Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2012 Feb 15;22 (4) :1565-8. Epub 2012 Jan 5. PMID: 22269110


Kim J, Roberts A, Yuan H, Xiong Y and Anderson KS: Nucleocapsid protein annealing of a primer-template enhances (+)-strand DNA synthesis and fidelity by HIV-1 reverse transcriptase. J Mol Biol. 2012 Feb 3;415 (5) :866-80. Epub 2011 Dec 23. PMID: 22210155

Bollini M, Domaoal RA, Thakur VV, Gallardo-Macias R, Spasov KA, Anderson KS and Jorgensen WL: Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents. J Med Chem. 2011 Dec 22;54 (24) :8582-91. Epub 2011 Nov 29. PMID: 22081993


Jorgensen WL, Bollini M, Thakur VV, Domaoal RA, Spasov KA and Anderson KS: Efficient discovery of potent anti-HIV agents targeting the Tyr181Cys variant of HIV reverse transcriptase. J Am Chem Soc. 2011 Oct 5;133 (39) :15686-96. Epub 2011 Sep 9. PMID: 21853995


Dermenci A, Selig PS, Domaoal RA, Spasov KA, Anderson KS and Miller SJ: Quasi-Biomimetic Ring Contraction Catalyzed by a Cysteine-Based Nucleophile: Total Synthesis of Sch-642305, Some Analogs and their Putative anti-HIV Activities. Chem Sci. 2011 Aug 1;2 (8) PMID: 24179673


Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker SR, Bloushtain-Qimron N, Kim JJ, Choudhury SA, Maruyama R, Wu Z, Gönen M, Mulvey LA, Bessarabova MO, Huh SJ, Silver SJ, Kim SY, Park SY, Lee HE, Anderson KS, Richardson AL, Nikolskaya T, Nikolsky Y, Liu XS, Root DE, Hahn WC, Frank DA and Polyak K: The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. J Clin Invest. 2011 Jul;121 (7) :2723-35. PMID: 21633165


Anderson KS, Wong J, D'Souza G, Riemer AB, Lorch J, Haddad R, Pai SI, Longtine J, McClean M, LaBaer J, Kelsey KT and Posner M: Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. Br J Cancer. 2011 Jun 7;104 (12) :1896-905. PMID: 21654689


Anderson KS, Zeng W, Sasada T, Choi J, Riemer AB, Su M, Drakoulakos D, Kang YJ, Brusic V, Wu C and Reinherz EL: Impaired tumor antigen processing by immunoproteasome-expressing CD40-activated B cells and dendritic cells. Cancer Immunol Immunother. 2011 Jun;60 (6) :857-67. Epub 2011 Mar 13. PMID: 21400024


Chen J, Yao Y, Gong C, Yu F, Su S, Chen J, Liu B, Deng H, Wang F, Lin L, Yao H, Su F, Anderson KS, Liu Q, Ewen ME, Yao X and Song E: CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell. 2011 Apr 12;19 (4) :541-55. PMID: 21481794


Yang C, Hayashida T, Forster N, Li C, Shen D, Maheswaran S, Chen L, Anderson KS, Ellisen LW, Sgroi D and Schmidt EV: The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers. Cancer Res. 2011 Feb 1;71 (3) :937-45. Epub 2010 Dec 2. PMID: 21127199


Anderson KS, Sibani S, Wallstrom G, Qiu J, Mendoza EA, Raphael J, Hainsworth E, Montor WR, Wong J, Park JG, Lokko N, Logvinenko T, Ramachandran N, Godwin AK, Marks J, Engstrom P and Labaer J: Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer. J Proteome Res. 2011 Jan 7;10 (1) :85-96. Epub 2010 Nov 23. PMID: 20977275


Poursina M, Bhalerao KD, Flores SC, Anderson KS and Laederach A: Strategies for articulated multibody-based adaptive coarse grain simulation of RNA. Methods Enzymol. 2011;487 :73-98. PMID: 21187222


Anderson KS: Multiplexed detection of antibodies using programmable bead arrays. Methods Mol Biol. 2011;723 :227-38. PMID: 21370069

Anderson KS, Petersson S, Wong J, Shubbar E, Lokko NN, Carlström M and Enerbäck C: Elevation of serum epidermal growth factor and interleukin 1 receptor antagonist in active psoriasis vulgaris. Br J Dermatol. 2010 Nov;163 (5) :1085-9. PMID: 20716221


Riemer AB, Keskin DB, Zhang G, Handley M, Anderson KS, Brusic V, Reinhold B and Reinherz EL: A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers. J Biol Chem. 2010 Sep 17;285 (38) :29608-22. Epub 2010 Jul 8. PMID: 20615877


Garforth SJ, Domaoal RA, Lwatula C, Landau MJ, Meyer AJ, Anderson KS and Prasad VR: K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies. J Mol Biol. 2010 Aug 6;401 (1) :33-44. Epub 2010 Jun 9. PMID: 20538005


Anderson KS: A transient kinetic approach to investigate nucleoside inhibitors of mitochondrial DNA polymerase gamma. Methods. 2010 Aug;51 (4) :392-8. Epub 2010 May 31. PMID: 20573564


Roberts A, Furdui C and Anderson KS: Observation of a chemically labile, noncovalent enzyme intermediate in the reaction of metal-dependent Aquifex pyrophilus KDO8PS by time-resolved mass spectrometry. Rapid Commun Mass Spectrom. 2010 Jul 15;24 (13) :1919-24. PMID: 20533322


Younis Y, Hunter R, Muhanji CI, Hale I, Singh R, Bailey CM, Sullivan TJ and Anderson KS: [d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase. Bioorg Med Chem. 2010 Jul 1;18 (13) :4661-73. Epub 2010 May 11. PMID: 20605472


Stumpf JD, Bailey CM, Spell D, Stillwagon M, Anderson KS and Copeland WC: mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae. Hum Mol Genet. 2010 Jun 1;19 (11) :2123-33. Epub 2010 Feb 25. PMID: 20185557


Bailey CM and Anderson KS: A mechanistic view of human mitochondrial DNA polymerase gamma: providing insight into drug toxicity and mitochondrial disease. Biochim Biophys Acta. 2010 May;1804 (5) :1213-22. Epub 2010 Jan 18. PMID: 20083238


Leung CS, Zeevaart JG, Domaoal RA, Bollini M, Thakur VV, Spasov KA, Anderson KS and Jorgensen WL: Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives. Bioorg Med Chem Lett. 2010 Apr 15;20 (8) :2485-8. Epub 2010 Mar 4. PMID: 20304641


Chang PY, Betti R, Spears BK, Anderson KS, Edwards J, Fatenejad M, Lindl JD, McCrory RL, Nora R and Shvarts D: Generalized measurable ignition criterion for inertial confinement fusion. Phys Rev Lett. 2010 Apr 2;104 (13) :135002. Epub 2010 Apr 1. PMID: 20481889


Anderson KS and Bjorklund P: Demystifying federal nursing home regulations to improve the effectiveness of psychopharmacological care. Perspect Psychiatr Care. 2010 Apr;46 (2) :152-62. PMID: 20377803


Anderson KS, Wong J, Vitonis A, Crum CP, Sluss PM, Labaer J and Cramer D: p53 autoantibodies as potential detection and prognostic biomarkers in serous ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2010 Mar;19 (3) :859-68. Epub 2010 Mar 3. PMID: 20200435


Cole K, Tabernero M and Anderson KS: Biologic characteristics of premalignant breast disease. Cancer Biomark. 2010;9 (1-6) :177-92. PMID: 22112476


Tabernero MD, Lv LL and Anderson KS: Autoantibody profiles as biomarkers of breast cancer. Cancer Biomark. 2010;6 (5-6) :247-56. PMID: 20938085

Parker CG, Domaoal RA, Anderson KS and Spiegel DA: An antibody-recruiting small molecule that targets HIV gp120. J Am Chem Soc. 2009 Nov 18;131 (45) :16392-4. PMID: 19839582


Li Z, Song F, Zhuang Z, Dunaway-Mariano D and Anderson KS: Monitoring enzyme catalysis in the multimeric state: direct observation of Arthrobacter 4-hydroxybenzoyl-coenzyme A thioesterase catalytic complexes using time-resolved electrospray ionization mass spectrometry. Anal Biochem. 2009 Nov 15;394 (2) :209-16. Epub 2009 Jul 25. PMID: 19635449


Anderson KS, Mullally VM, Fredrick LM and Campbell AL: Compliance with RSV prophylaxis: Global physicians' perspectives. Patient Prefer Adherence. 2009 Nov 3;3 :195-203. Epub 2009 Nov 3. PMID: 19936162


Wong J, Sibani S, Lokko NN, LaBaer J and Anderson KS: Rapid detection of antibodies in sera using multiplexed self-assembling bead arrays. J Immunol Methods. 2009 Oct 31;350 (1-2) :171-82. Epub 2009 Sep 2. PMID: 19732778


Bautista AD, Stephens OM, Wang L, Domaoal RA, Anderson KS and Schepartz A: Identification of a beta3-peptide HIV fusion inhibitor with improved potency in live cells. Bioorg Med Chem Lett. 2009 Jul 15;19 (14) :3736-8. Epub 2009 May 15. PMID: 19497744


Bailey CM, Kasiviswanathan R, Copeland WC and Anderson KS: R964C mutation of DNA polymerase gamma imparts increased stavudine toxicity by decreasing nucleoside analog discrimination and impairing polymerase activity. Antimicrob Agents Chemother. 2009 Jun;53 (6) :2610-2. Epub 2009 Apr 13. PMID: 19364868


Hawranik DJ, Anderson KS, Simmonds R and Sorensen JL: The chemoenzymatic synthesis of usnic acid. Bioorg Med Chem Lett. 2009 May 1;19 (9) :2383-5. Epub 2009 Mar 26. PMID: 19349177


Anderson KS: Tumor vaccines for breast cancer. Cancer Invest. 2009 May;27 (4) :361-8. PMID: 19358018


Nichols SE, Domaoal RA, Thakur VV, Tirado-Rives J, Anderson KS and Jorgensen WL: Discovery of wild-type and Y181C mutant non-nucleoside HIV-1 reverse transcriptase inhibitors using virtual screening with multiple protein structures. J Chem Inf Model. 2009 May;49 (5) :1272-9. PMID: 19374380


Mirshahidi S, Kramer VG, Whitney JB, Essono S, Lee S, Dranoff G, Anderson KS and Ruprecht RM: Overlapping synthetic peptides encoding TPD52 as breast cancer vaccine in mice: prolonged survival. Vaccine. 2009 Mar 13;27 (12) :1825-33. Epub 2009 Feb 6. PMID: 19201387


Lew ED, Furdui CM, Anderson KS and Schlessinger J: The precise sequence of FGF receptor autophosphorylation is kinetically driven and is disrupted by oncogenic mutations. Sci Signal. 2009 Feb 17;2 (58) :ra6. Epub 2009 Feb 17. PMID: 19224897


Vargo MA, Martucci WE and Anderson KS: Disruption of the crossover helix impairs dihydrofolate reductase activity in the bifunctional enzyme TS-DHFR from Cryptosporidium hominis. Biochem J. 2009 Feb 1;417 (3) :757-64. PMID: 18851711


Anderson KS, Wong J, Polyak K, Aronzon D and Enerbäck C: Detection of psoriasin/S100A7 in the sera of patients with psoriasis. Br J Dermatol. 2009 Feb;160 (2) :325-32. Epub 2008 Oct 21. PMID: 19016707


Dasgupta T, Chitnumsub P, Kamchonwongpaisan S, Maneeruttanarungroj C, Nichols SE, Lyons TM, Tirado-Rives J, Jorgensen WL, Yuthavong Y and Anderson KS: Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria. ACS Chem Biol. 2009 Jan 16;4 (1) :29-40. PMID: 19146480


Martucci WE, Udier-Blagovic M, Atreya C, Babatunde O, Vargo MA, Jorgensen WL and Anderson KS: Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen. Bioorg Med Chem Lett. 2009 Jan 15;19 (2) :418-23. Epub 2008 Nov 20. PMID: 19059777

Hunter R, Younis Y, Muhanji CI, Curtin TL, Naidoo KJ, Petersen M, Bailey CM, Basavapathruni A and Anderson KS: C-2-aryl O-substituted HI-236 derivatives as non-nucleoside HIV-1 reverse-transcriptase inhibitors. Bioorg Med Chem. 2008 Dec 15;16 (24) :10270-80. Epub 2008 Nov 1. PMID: 18996020


Ramachandran N, Anderson KS, Raphael JV, Hainsworth E, Sibani S, Montor WR, Pacek M, Wong J, Eljanne M, Sanda MG, Hu Y, Logvinenko T and Labaer J: Tracking humoral responses using self assembling protein microarrays. Proteomics Clin Appl. 2008 Oct;2 (10-11) :1518-27. Epub 2008 Sep 10. PMID: 21136799


Martucci WE, Vargo MA and Anderson KS: Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase. Biochemistry. 2008 Aug 26;47 (34) :8902-11. Epub 2008 Aug 2. PMID: 18672899


Zeevaart JG, Wang L, Thakur VV, Leung CS, Tirado-Rives J, Bailey CM, Domaoal RA, Anderson KS and Jorgensen WL: Optimization of azoles as anti-human immunodeficiency virus agents guided by free-energy calculations. J Am Chem Soc. 2008 Jul 23;130 (29) :9492-9. Epub 2008 Jun 28. PMID: 18588301


Shen L, Peterson S, Sedaghat AR, McMahon MA, Callender M, Zhang H, Zhou Y, Pitt E, Anderson KS, Acosta EP and Siliciano RF: Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nat Med. 2008 Jul;14 (7) :762-6. Epub 2008 Jun 15. PMID: 18552857


Anderson KS, Ramachandran N, Wong J, Raphael JV, Hainsworth E, Demirkan G, Cramer D, Aronzon D, Hodi FS, Harris L, Logvinenko T and LaBaer J: Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. J Proteome Res. 2008 Apr;7 (4) :1490-9. Epub 2008 Feb 27. PMID: 18311903


Domaoal RA, McMahon M, Thio CL, Bailey CM, Tirado-Rives J, Obikhod A, Detorio M, Rapp KL, Siliciano RF, Schinazi RF and Anderson KS: Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. J Biol Chem. 2008 Feb 29;283 (9) :5452-9. Epub 2007 Oct 25. PMID: 17962184


Dasgupta T and Anderson KS: Probing the role of parasite-specific, distant structural regions on communication and catalysis in the bifunctional thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum. Biochemistry. 2008 Feb 5;47 (5) :1336-45. Epub 2008 Jan 12. PMID: 18189414

Basavapathruni A and Anderson KS: Reverse transcription of the HIV-1 pandemic. FASEB J. 2007 Dec;21 (14) :3795-808. Epub 2007 Jul 17. PMID: 17639073


Barreiro G, Kim JT, Guimarães CR, Bailey CM, Domaoal RA, Wang L, Anderson KS and Jorgensen WL: From docking false-positive to active anti-HIV agent. J Med Chem. 2007 Nov 1;50 (22) :5324-9. Epub 2007 Oct 6. PMID: 17918923


Nakata H, Amano M, Koh Y, Kodama E, Yang G, Bailey CM, Kohgo S, Hayakawa H, Matsuoka M, Anderson KS, Cheng YC and Mitsuya H: Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine. Antimicrob Agents Chemother. 2007 Aug;51 (8) :2701-8. Epub 2007 Jun 4. PMID: 17548498


Xia Q, Radzio J, Anderson KS and Sluis-Cremer N: Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses. Protein Sci. 2007 Aug;16 (8) :1728-37. PMID: 17656585


Doan LT, Martucci WE, Vargo MA, Atreya CE and Anderson KS: Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis. Biochemistry. 2007 Jul 17;46 (28) :8379-91. Epub 2007 Jun 20. PMID: 17580969


Hunter R, Muhanji CI, Hale I, Bailey CM, Basavapathruni A and Anderson KS: [d4U]-butyne-[HI-236] as a non-cleavable, bifunctional NRTI/NNRTI HIV-1 reverse-transcriptase inhibitor. Bioorg Med Chem Lett. 2007 May 1;17 (9) :2614-7. Epub 2007 Feb 4. PMID: 17317163


Betti R, Zhou CD, Anderson KS, Perkins LJ, Theobald W and Solodov AA: Shock ignition of thermonuclear fuel with high areal density. Phys Rev Lett. 2007 Apr 13;98 (15) :155001. Epub 2007 Apr 12. PMID: 17501359


Yang G, Dutschman GE, Wang CJ, Tanaka H, Baba M, Anderson KS and Cheng YC: Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT. Antiviral Res. 2007 Mar;73 (3) :185-91. Epub 2006 Nov 10. PMID: 17109975


Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J, Nikolskaya T, Serebryiskaya T, Beroukhim R, Hu M, Halushka MK, Sukumar S, Parker LM, Anderson KS, Harris LN, Garber JE, Richardson AL, Schnitt SJ, Nikolsky Y, Gelman RS and Polyak K: Molecular definition of breast tumor heterogeneity. Cancer Cell. 2007 Mar;11 (3) :259-73. PMID: 17349583


Mulloy R, Ferrand A, Kim Y, Sordella R, Bell DW, Haber DA, Anderson KS and Settleman J: Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib. Cancer Res. 2007 Mar 1;67 (5) :2325-30. PMID: 17332364


Zhou CD, Theobald W, Betti R, Radha PB, Smalyuk VA, Shvarts D, Glebov VY, Stoeckl C, Anderson KS, Meyerhofer DD, Sangster TC, Li CK, Petrasso RD, Frenje JA and Seguin FH: High-rhoR implosions for fast-ignition fuel assembly. Phys Rev Lett. 2007 Jan 12;98 (2) :025004. Epub 2007 Jan 11. PMID: 17358616


Murakami E, Bao H, Basavapathruni A, Bailey CM, Du J, Steuer HM, Niu C, Whitaker T, Anderson KS, Otto MJ and Furman PA: Mechanism of action of (-)-(2R,4R)-1-(2-hydroxymethyl-1,3-dioxolan-4-yl) thymine as an anti-HIV agent. Antivir Chem Chemother. 2007;18 (2) :83-92. PMID: 17542153


Ray AS, Feng JY, Murakami E, Chu CK, Schinazi RF and Anderson KS: Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma. Antivir Chem Chemother. 2007;18 (1) :25-33. PMID: 17354649

Kim JT, Hamilton AD, Bailey CM, Domaoal RA, Wang L, Anderson KS and Jorgensen WL: FEP-guided selection of bicyclic heterocycles in lead optimization for non-nucleoside inhibitors of HIV-1 reverse transcriptase. J Am Chem Soc. 2006 Dec 6;128 (48) :15372-3. PMID: 17131993


Thakur VV, Kim JT, Hamilton AD, Bailey CM, Domaoal RA, Wang L, Anderson KS and Jorgensen WL: Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2006 Nov 1;16 (21) :5664-7. Epub 2006 Aug 22. PMID: 16931015


Massimine KM, McIntosh MT, Doan LT, Atreya CE, Gromer S, Sirawaraporn W, Elliott DA, Joiner KA, Schirmer RH and Anderson KS: Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparum. Antimicrob Agents Chemother. 2006 Sep;50 (9) :3132-41. PMID: 16940112


Zellars KL, Perrewé PL, Hochwarter WA and Anderson KS: The interactive effects of positive affect and conscientiousness on strain. J Occup Health Psychol. 2006 Jul;11 (3) :281-9. PMID: 16834475


Basavapathruni A, Vingerhoets J, de Béthune MP, Chung R, Bailey CM, Kim J and Anderson KS: Modulation of human immunodeficiency virus type 1 synergistic inhibition by reverse transcriptase mutations. Biochemistry. 2006 Jun 13;45 (23) :7334-40. PMID: 16752922


Furdui CM, Lew ED, Schlessinger J and Anderson KS: Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction. Mol Cell. 2006 Mar 3;21 (5) :711-7. PMID: 16507368


Ruiz-Caro J, Basavapathruni A, Kim JT, Bailey CM, Wang L, Anderson KS, Hamilton AD and Jorgensen WL: Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2006 Feb;16 (3) :668-71. Epub 2005 Nov 17. PMID: 16298131


Jorgensen WL, Ruiz-Caro J, Tirado-Rives J, Basavapathruni A, Anderson KS and Hamilton AD: Computer-aided design of non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2006 Feb;16 (3) :663-7. Epub 2005 Nov 2. PMID: 16263277


Basavapathruni A and Anderson KS: Developing novel nonnucleoside HIV-1 reverse transcriptase inhibitors: beyond the butterfly. Curr Pharm Des. 2006;12 (15) :1857-65. PMID: 16724952

Ward BM, Anderson KS and Sheldon MS: Patterns of home and community care service delivery to culturally and linguistically diverse residents of rural Victoria. Aust J Rural Health. 2005 Dec;13 (6) :348-52. PMID: 16313530


Massimine KM, Doan LT, Atreya CA, Stedman TT, Anderson KS, Joiner KA and Coppens I: Toxoplasma gondii is capable of exogenous folate transport. A likely expansion of the BT1 family of transmembrane proteins. Mol Biochem Parasitol. 2005 Nov;144 (1) :44-54. PMID: 16159678


Maecker B, von Bergwelt-Baildon MS, Anderson KS, Vonderheide RH, Anderson KC, Nadler LM and Schultze JL: Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients. Clin Exp Immunol. 2005 Sep;141 (3) :558-62. PMID: 16045747


Weihrauch MR, Ansén S, Jurkiewicz E, Geisen C, Xia Z, Anderson KS, Gracien E, Schmidt M, Wittig B, Diehl V, Wolf J, Bohlen H and Nadler LM: Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer. Clin Cancer Res. 2005 Aug 15;11 (16) :5993-6001. PMID: 16115944


Li Z, Sau AK, Furdui CM and Anderson KS: Probing the role of tightly bound phosphoenolpyruvate in Escherichia coli 3-deoxy-d-manno-octulosonate 8-phosphate synthase catalysis using quantitative time-resolved electrospray ionization mass spectrometry in the millisecond time range. Anal Biochem. 2005 Aug 1;343 (1) :35-47. PMID: 15979047


Murakami E, Basavapathruni A, Bradley WD and Anderson KS: Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases. Antiviral Res. 2005 Jul;67 (1) :10-7. Epub 2005 Jan 26. PMID: 15950748


Anderson KS and LaBaer J: The sentinel within: exploiting the immune system for cancer biomarkers. J Proteome Res. 2005 Jul-Aug;4 (4) :1123-33. PMID: 16083262


Furdui CM, Sau AK, Yaniv O, Belakhov V, Woodard RW, Baasov T and Anderson KS: The use of (E)- and (Z)-phosphoenol-3-fluoropyruvate as mechanistic probes reveals significant differences between the active sites of KDO8P and DAHP synthases. Biochemistry. 2005 May 17;44 (19) :7326-35. PMID: 15882071


Ray AS, Hernandez-Santiago BI, Mathew JS, Murakami E, Bozeman C, Xie MY, Dutschman GE, Gullen E, Yang Z, Hurwitz S, Cheng YC, Chu CK, McClure H, Schinazi RF and Anderson KS: Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine. Antimicrob Agents Chemother. 2005 May;49 (5) :1994-2001. PMID: 15855524


Bae C, Hartwig JF, Boaen Harris NK, Long RO, Anderson KS and Hillmyer MA: Catalytic hydroxylation of polypropylenes. J Am Chem Soc. 2005 Jan 19;127 (2) :767-76. PMID: 15643903


Anderson KS: Detection of novel enzyme intermediates in PEP-utilizing enzymes. Arch Biochem Biophys. 2005 Jan 1;433 (1) :47-58. PMID: 15581565


Gündogdu O, Anderson KS and Parnianpour M: Simulation of manual materials handling: biomechanial assessment under different lifting conditions. Technol Health Care. 2005;13 (1) :57-66. PMID: 15706064

Furdui C, Zhou L, Woodard RW and Anderson KS: Insights into the mechanism of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (Phe) from Escherichia coli using a transient kinetic analysis. J Biol Chem. 2004 Oct 29;279 (44) :45618-25. Epub 2004 Aug 23. PMID: 15326172


Shulami S, Furdui C, Adir N, Shoham Y, Anderson KS and Baasov T: A reciprocal single mutation affects the metal requirement of 3-deoxy-D-manno-2-octulosonate-8-phosphate (KDO8P) synthases from Aquifex pyrophilus and Escherichia coli. J Biol Chem. 2004 Oct 22;279 (43) :45110-20. Epub 2004 Aug 12. PMID: 15308670


Folta-Stogniew E, O'Malley S, Gupta R, Anderson KS and Radding CM: Exchange of DNA base pairs that coincides with recognition of homology promoted by E. coli RecA protein. Mol Cell. 2004 Sep 24;15 (6) :965-75. PMID: 15383285


Shi J, Ray AS, Mathew JS, Anderson KS, Chu CK and Schinazi RF: 2('),3(')-didehydro-2('),3(')-dideoxynucleosides are degraded to furfuryl alcohol under acidic conditions. Bioorg Med Chem Lett. 2004 May 3;14 (9) :2159-62. PMID: 15081000


Atreya CE and Anderson KS: Kinetic characterization of bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from Cryptosporidium hominis: a paradigm shift for ts activity and channeling behavior. J Biol Chem. 2004 Apr 30;279 (18) :18314-22. Epub 2004 Feb 12. PMID: 14966126


Sau AK, Li Z and Anderson KS: Probing the role of metal ions in the catalysis of Helicobacter pylori 3-deoxy-D-manno-octulosonate-8-phosphate synthase using a transient kinetic analysis. J Biol Chem. 2004 Apr 16;279 (16) :15787-94. Epub 2003 Dec 30. PMID: 14701842


Feng JY, Murakami E, Zorca SM, Johnson AA, Johnson KA, Schinazi RF, Furman PA and Anderson KS: Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase. Antimicrob Agents Chemother. 2004 Apr;48 (4) :1300-6. PMID: 15047533


Murakami E, Ray AS, Schinazi RF and Anderson KS: Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of D- and L-D4FC-TP. Antiviral Res. 2004 Apr;62 (1) :57-64. PMID: 15026203


Basavapathruni A, Bailey CM and Anderson KS: Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs. J Biol Chem. 2004 Feb 20;279 (8) :6221-4. Epub 2004 Jan 13. PMID: 14722107


Vonderheide RH, Domchek SM, Schultze JL, George DJ, Hoar KM, Chen DY, Stephans KF, Masutomi K, Loda M, Xia Z, Anderson KS, Hahn WC and Nadler LM: Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res. 2004 Feb 1;10 (3) :828-39. PMID: 14871958

Maecker B, Sherr DH, Vonderheide RH, von Bergwelt-Baildon MS, Hirano N, Anderson KS, Xia Z, Butler MO, Wucherpfennig KW, O'Hara C, Cole G, Kwak SS, Ramstedt U, Tomlinson AJ, Chicz RM, Nadler LM and Schultze JL: The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood. 2003 Nov 1;102 (9) :3287-94. Epub 2003 Jul 17. PMID: 12869499


Liu F, Johnson EF, Austin DJ and Anderson KS: Adenosine-anchored triphosphate subsite probing: distinguishing between HER-2 and HER-4 tyrosine protein kinases. Bioorg Med Chem Lett. 2003 Oct 20;13 (20) :3587-92. PMID: 14505676


Murakami E, Feng JY, Lee H, Hanes J, Johnson KA and Anderson KS: Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication. J Biol Chem. 2003 Sep 19;278 (38) :36403-9. Epub 2003 Jul 10. PMID: 12857740


Li Z, Sau AK, Shen S, Whitehouse C, Baasov T and Anderson KS: A snapshot of enzyme catalysis using electrospray ionization mass spectrometry. J Am Chem Soc. 2003 Aug 20;125 (33) :9938-9. PMID: 12914453


Atreya CE, Johnson EF, Williamson J, Chang SY, Liang PH and Anderson KS: Probing electrostatic channeling in protozoal bifunctional thymidylate synthase-dihydrofolate reductase using site-directed mutagenesis. J Biol Chem. 2003 Aug 1;278 (31) :28901-11. Epub 2003 May 17. PMID: 12754260


Ray AS, Murakami E, Basavapathruni A, Vaccaro JA, Ulrich D, Chu CK, Schinazi RF and Anderson KS: Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis. Biochemistry. 2003 Jul 29;42 (29) :8831-41. PMID: 12873144


Maecker B, Anderson KS, von Bergwelt-Baildon MS, Weller E, Vonderheide RH, Richardson PG, Schlossman RL, Menezes IA, Xia Z, Munshi NC, Anderson KC, Nadler LM and Schultze JL: Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. Br J Haematol. 2003 Jun;121 (6) :842-8. PMID: 12786794


Jeffrey JL, Feng JY, Qi CC, Anderson KS and Furman PA: Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses. J Biol Chem. 2003 May 23;278 (21) :18971-9. Epub 2003 Mar 21. PMID: 12651859


Ray AS, Schinazi RF, Murakami E, Basavapathruni A, Shi J, Zorca SM, Chu CK and Anderson KS: Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase. Antivir Chem Chemother. 2003 May;14 (3) :115-25. PMID: 14521328


Atreya CE, Johnson EF, Irwin JJ, Dow A, Massimine KM, Coppens I, Stempliuk V, Beverley S, Joiner KA, Shoichet BK and Anderson KS: A molecular docking strategy identifies Eosin B as a non-active site inhibitor of protozoal bifunctional thymidylate synthase-dihydrofolate reductase. J Biol Chem. 2003 Apr 18;278 (16) :14092-100. Epub 2003 Jan 29. PMID: 12556445

Ray AS, Murakami E, Peterson CN, Shi J, Schinazi RF and Anderson KS: Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase. Antiviral Res. 2002 Dec;56 (3) :189-205. PMID: 12406504


Johnson EF, Hinz W, Atreya CE, Maley F and Anderson KS: Mechanistic characterization of Toxoplasma gondii thymidylate synthase (TS-DHFR)-dihydrofolate reductase. Evidence for a TS intermediate and TS half-sites reactivity. J Biol Chem. 2002 Nov 8;277 (45) :43126-36. Epub 2002 Aug 20. PMID: 12192007


Ray AS, Basavapathruni A and Anderson KS: Mechanistic studies to understand the progressive development of resistance in human immunodeficiency virus type 1 reverse transcriptase to abacavir. J Biol Chem. 2002 Oct 25;277 (43) :40479-90. Epub 2002 Aug 9. PMID: 12176989


Anderson KS: Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase. Biochim Biophys Acta. 2002 Jul 18;1587 (2-3) :296-9. PMID: 12084471


Bulock KG, Beardsley GP and Anderson KS: The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling. J Biol Chem. 2002 Jun 21;277 (25) :22168-74. Epub 2002 Apr 10. PMID: 11948179


von Bergwelt-Baildon MS, Vonderheide RH, Maecker B, Hirano N, Anderson KS, Butler MO, Xia Z, Zeng WY, Wucherpfennig KW, Nadler LM and Schultze JL: Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood. 2002 May 1;99 (9) :3319-25. PMID: 11964299


Ray AS, Yang Z, Shi J, Hobbs A, Schinazi RF, Chu CK and Anderson KS: Insights into the molecular mechanism of inhibition and drug resistance for HIV-1 RT with carbovir triphosphate. Biochemistry. 2002 Apr 23;41 (16) :5150-62. PMID: 11955063


Ray AS, Yang Z, Chu CK and Anderson KS: Novel use of a guanosine prodrug approach to convert 2',3'-didehydro-2',3'-dideoxyguanosine into a viable antiviral agent. Antimicrob Agents Chemother. 2002 Mar;46 (3) :887-91. PMID: 11850281

Vonderheide RH, Schultze JL, Anderson KS, Maecker B, Butler MO, Xia Z, Kuroda MJ, von Bergwelt-Baildon MS, Bedor MM, Hoar KM, Schnipper DR, Brooks MW, Letvin NL, Stephans KF, Wucherpfennig KW, Hahn WC and Nadler LM: Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals. Cancer Res. 2001 Dec 1;61 (23) :8366-70. PMID: 11731409


Johnson AA, Ray AS, Hanes J, Suo Z, Colacino JM, Anderson KS and Johnson KA: Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase. J Biol Chem. 2001 Nov 2;276 (44) :40847-57. Epub 2001 Aug 28. PMID: 11526116


Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL and Nadler LM: Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin Cancer Res. 2001 Nov;7 (11) :3343-8. PMID: 11705846


Maecker B, von Bergwelt-Baildon, Anderson KS, Vonderheide RH and Schultze JL: Linking genomics to immunotherapy by reverse immunology--'immunomics' in the new millennium. Curr Mol Med. 2001 Nov;1 (5) :609-19. PMID: 11899235


Krynetskaia NF, Feng JY, Krynetski EY, Garcia JV, Panetta JC, Anderson KS and Evans WE: Deoxythioguanosine triphosphate impairs HIV replication: a new mechanism for an old drug. FASEB J. 2001 Sep;15 (11) :1902-8. PMID: 11532970


Feng JY, Johnson AA, Johnson KA and Anderson KS: Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs. J Biol Chem. 2001 Jun 29;276 (26) :23832-7. Epub 2001 Apr 27. PMID: 11328813


Shah AM, Li SX, Anderson KS and Sweasy JB: Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity. J Biol Chem. 2001 Apr 6;276 (14) :10824-31. Epub 2001 Jan 11. PMID: 11154692


Ray AS and Anderson KS: Mechanistic studies to understand the inhibition of wild type and mutant HIV-1 reverse transcriptase by Carbovir-triphosphate. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20 (4-7) :1247-50. PMID: 11562995


Schultze JL, Maecker B, von Bergwelt-Baildon MS, Anderson KS and Vonderheide RH: Tumour immunotherapy: new tools, new treatment modalities and new T-cell antigens. Vox Sang. 2001 Feb;80 (2) :81-9. PMID: 11378969


Furman PA, Jeffrey J, Kiefer LL, Feng JY, Anderson KS, Borroto-Esoda K, Hill E, Copeland WC, Chu CK, Sommadossi JP, Liberman I, Schinazi RF and Painter GR: Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine. Antimicrob Agents Chemother. 2001 Jan;45 (1) :158-65. PMID: 11120959


Anderson KS: The molecular basis of inhibition and toxicity of modified cytosine analogues targetting HIV-1 reverse transcriptase. Antivir Chem Chemother. 2001;12 Suppl 1 :13-7. PMID: 11594679

Jan AY, Johnson EF, Diamonti AJ, Carraway III KL and Anderson KS: Insights into the HER-2 receptor tyrosine kinase mechanism and substrate specificity using a transient kinetic analysis. Biochemistry. 2000 Aug 15;39 (32) :9786-803. PMID: 10933796


McQueney MS, Anderson KS and Markham GD: Energetics of S-adenosylmethionine synthetase catalysis. Biochemistry. 2000 Apr 18;39 (15) :4443-54. PMID: 10757994


Furman PA, Painter GR and Anderson KS: An analysis of the catalytic cycle of HIV-1 reverse transcriptase: opportunities for chemotherapeutic intervention based on enzyme inhibition. Curr Pharm Des. 2000 Mar;6 (5) :547-67. PMID: 10788596


Vaccaro JA, Parnell KM, Terezakis SA and Anderson KS: Mechanism of inhibition of the human immunodeficiency virus type 1 reverse transcriptase by d4TTP: an equivalent incorporation efficiency relative to the natural substrate dTTP. Antimicrob Agents Chemother. 2000 Jan;44 (1) :217-21. PMID: 10602755

Vaccaro JA, Singh HA and Anderson KS: Initiation of minus-strand DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase. Biochemistry. 1999 Nov 30;38 (48) :15978-85. PMID: 10625465


Sachpatzidis A, Dealwis C, Lubetsky JB, Liang PH, Anderson KS and Lolis E: Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase. Biochemistry. 1999 Sep 28;38 (39) :12665-74. PMID: 10504236


Feng JY, Shi J, Schinazi RF and Anderson KS: Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP. FASEB J. 1999 Sep;13 (12) :1511-7. PMID: 10463941


Feng JY and Anderson KS: Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase. Biochemistry. 1999 Jul 20;38 (29) :9440-8. PMID: 10413520


Lewis J, Johnson KA and Anderson KS: The catalytic mechanism of EPSP synthase revisited. Biochemistry. 1999 Jun 1;38 (22) :7372-9. PMID: 10353849


Nagi AD, Anderson KS and Regan L: Using loop length variants to dissect the folding pathway of a four-helix-bundle protein. J Mol Biol. 1999 Feb 12;286 (1) :257-65. PMID: 9931264


Feng JY and Anderson KS: Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase. Biochemistry. 1999 Jan 5;38 (1) :55-63. PMID: 9890882


Anderson KS: Fundamental mechanisms of substrate channeling. Methods Enzymol. 1999;308 :111-45. PMID: 10507003

Liang PH, Lewis J, Anderson KS, Kohen A, D'Souza FW, Benenson Y and Baasov T: Catalytic mechanism of Kdo8P synthase: transient kinetic studies and evaluation of a putative reaction intermediate. Biochemistry. 1998 Nov 17;37 (46) :16390-9. PMID: 9819231


Vaccaro JA and Anderson KS: Implication of the tRNA initiation step for human immunodeficiency virus type 1 reverse transcriptase in the mechanism of 3'-azido-3'-deoxythymidine (AZT) resistance. Biochemistry. 1998 Oct 6;37 (40) :14189-94. PMID: 9760256


Liang PH and Anderson KS: Kinetic reaction scheme for the dihydrofolate reductase domain of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania major. Biochemistry. 1998 Sep 1;37 (35) :12206-12. PMID: 9724534


Liang PH and Anderson KS: Substrate channeling and domain-domain interactions in bifunctional thymidylate synthase-dihydrofolate reductase. Biochemistry. 1998 Sep 1;37 (35) :12195-205. PMID: 9724533


Buckingham W, Anderson KS and Davies CK: ECT seizure classification. Can J Anaesth. 1998 Jul;45 (7) :709. PMID: 9717611


Schneider TR, Gerhardt E, Lee M, Liang PH, Anderson KS and Schlichting I: Loop closure and intersubunit communication in tryptophan synthase. Biochemistry. 1998 Apr 21;37 (16) :5394-406. PMID: 9548921


Luba J, Nare B, Liang PH, Anderson KS, Beverley SM and Hardy LW: Leishmania major pteridine reductase 1 belongs to the short chain dehydrogenase family: stereochemical and kinetic evidence. Biochemistry. 1998 Mar 24;37 (12) :4093-104. PMID: 9521731


Beardsley GP, Rayl EA, Gunn K, Moroson BA, Seow H, Anderson KS, Vergis J, Fleming K, Worland S, Condon B and Davies J: Structure and functional relationships in human pur H. Adv Exp Med Biol. 1998;431 :221-6. PMID: 9598063

Smith CK, Bu Z, Anderson KS, Sturtevant JM, Engelman DM and Regan L: Surface point mutations that significantly alter the structure and stability of a protein's denatured state. Protein Sci. 1996 Oct;5 (10) :2009-19. PMID: 8897601


Anderson KS, Amos CS, Boppana S and Pass R: Ocular abnormalities in congenital cytomegalovirus infection. J Am Optom Assoc. 1996 May;67 (5) :273-8. PMID: 8888845


McDowell LM, Lee M, McKay RA, Anderson KS and Schaefer J: Intersubunit communication in tryptophan synthase by carbon-13 and fluorine-19 REDOR NMR. Biochemistry. 1996 Mar 12;35 (10) :3328-34. PMID: 8605170


Spence RA, Anderson KS and Johnson KA: HIV-1 reverse transcriptase resistance to nonnucleoside inhibitors. Biochemistry. 1996 Jan 23;35 (3) :1054-63. PMID: 8547241

Anderson KS, Kim AY, Quillen JM, Sayers E, Yang XJ and Miles EW: Kinetic characterization of channel impaired mutants of tryptophan synthase. J Biol Chem. 1995 Dec 15;270 (50) :29936-44. PMID: 8530393


Sammons RD, Gruys KJ, Anderson KS, Johnson KA and Sikorski JA: Reevaluating glyphosate as a transition-state inhibitor of EPSP synthase: identification of an EPSP synthase.EPSP.glyphosate ternary complex. Biochemistry. 1995 May 16;34 (19) :6433-40. PMID: 7756274


Hoffmann K, Kakalis LT, Anderson KS, Armitage IM and Handschumacher RE: Expression of human cyclophilin-40 and the effect of the His141--&gt;Trp mutation on catalysis and cyclosporin A binding. Eur J Biochem. 1995 Apr 1;229 (1) :188-93. PMID: 7744028


Spence RA, Kati WM, Anderson KS and Johnson KA: Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors. Science. 1995 Feb 17;267 (5200) :988-93. PMID: 7532321

Schlichting I, Yang XJ, Miles EW, Kim AY and Anderson KS: Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase. J Biol Chem. 1994 Oct 28;269 (43) :26591-3. PMID: 7929385


Brown ED, Marquardt JL, Lee JP, Walsh CT and Anderson KS: Detection and characterization of a phospholactoyl-enzyme adduct in the reaction catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase, MurZ. Biochemistry. 1994 Sep 6;33 (35) :10638-45. PMID: 8075064


Anderson KS and Cresswell P: A role for calnexin (IP90) in the assembly of class II MHC molecules. EMBO J. 1994 Feb 1;13 (3) :675-82. PMID: 8313912

Anderson KS, Alexander J, Wei M and Cresswell P: Intracellular transport of class I MHC molecules in antigen processing mutant cell lines. J Immunol. 1993 Oct 1;151 (7) :3407-19. PMID: 8376783


Androlewicz MJ, Anderson KS and Cresswell P: Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. Proc Natl Acad Sci U S A. 1993 Oct 1;90 (19) :9130-4. PMID: 8415666

Kati WM, Johnson KA, Jerva LF and Anderson KS: Mechanism and fidelity of HIV reverse transcriptase. J Biol Chem. 1992 Dec 25;267 (36) :25988-97. PMID: 1281479


Click EM, Anderson KS, Androlewicz MJ, Wei ML and Cresswell P: Transport and expression of class I MHC glycoproteins in an antigen-processing mutant cell line. Cold Spring Harb Symp Quant Biol. 1992;57 :571-7. PMID: 1339695

Stallings WC, Abdel-Meguid SS, Lim LW, Shieh HS, Dayringer HE, Leimgruber NK, Stegeman RA, Anderson KS, Sikorski JA, Padgette SR and Kishore GM: Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold. Proc Natl Acad Sci U S A. 1991 Jun 1;88 (11) :5046-50. PMID: 11607190


Anderson KS, Miles EW and Johnson KA: Serine modulates substrate channeling in tryptophan synthase. A novel intersubunit triggering mechanism. J Biol Chem. 1991 May 5;266 (13) :8020-33. PMID: 1902468

Anderson KS and Johnson KA: "Kinetic competence" of the 5-enolpyruvoylshikimate-3-phosphate synthase tetrahedral intermediate. J Biol Chem. 1990 Apr 5;265 (10) :5567-72. PMID: 2180929


Anderson KS, Sammons RD, Leo GC, Sikorski JA, Benesi AJ and Johnson KA: Observation by 13C NMR of the EPSP synthase tetrahedral intermediate bound to the enzyme active site. Biochemistry. 1990 Feb 13;29 (6) :1460-5. PMID: 2334707

Anderson KS, Sikorski JA and Johnson KA: A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics. Biochemistry. 1988 Sep 20;27 (19) :7395-406. PMID: 3061457


Pearson WR, Reinhart J, Sisk SC, Anderson KS and Adler PN: Tissue-specific induction of murine glutathione transferase mRNAs by butylated hydroxyanisole. J Biol Chem. 1988 Sep 15;263 (26) :13324-32. PMID: 3417659


Anderson KS, Sikorski JA and Johnson KA: Evaluation of 5-enolpyruvoylshikimate-3-phosphate synthase substrate and inhibitor binding by stopped-flow and equilibrium fluorescence measurements. Biochemistry. 1988 Mar 8;27 (5) :1604-10. PMID: 3284585


Main AJ, Anderson KS, Maxfield HK, Rosenau B and Oliver C: Duration of Alphavirus neutralizing antibody in naturally infected birds. Am J Trop Med Hyg. 1988 Jan;38 (1) :208-17. PMID: 2829638

Huzoor-Akbar, Mukhopadhyay A, Anderson KS, Navran SS, Romstedt K, Miller DD and Feller DR: Antagonism of prostaglandin-mediated responses in platelets and vascular smooth muscle by 13-azaprostanoic acid analogs. Evidence for selective blockade of thromboxane A2 responses. Biochem Pharmacol. 1985 Mar 1;34 (5) :641-7. PMID: 3156599

Anderson KS and Kendall JD: A review of succinylcholine-induced apnea. AANA J. 1982 Aug;50 (4) :363-8. PMID: 6293235


Ruffolo RR Jr, Anderson KS and Miller DD: Conformational requirements of alpha 2-adrenergic receptors. Mol Pharmacol. 1982 Mar;21 (2) :259-61. PMID: 6285164

Anderson KS: Operative treatment of congenital pseudarthrosis of the tibia. Acta Orthop Scand. 1974;45 (6) :935-44. PMID: 4463693

HAYES RO, DANIELS JB, ANDERSON KS, PARSONS MA, MAXFIELD HK and LAMOTTE LC: Detection of eastern encephalitis virus and antibody in wild and domestic birds in Massachusetts. Am J Hyg. 1962 Mar;75 :183-9. PMID: 13905654